Event Details

Background

The meeting is designed to bring together experts in neuroscience, neurocognition, neuroimaging, neurotechnology development and application, and obesity and diabetes to review the state of the science and technology in the neuroimaging and modulation space for obesity and diabetes-relevant research to help guide future research directions.

Meeting Objectives

The purpose of the meeting is to look back on the past 10 years of what has been done in the neuroimaging and modulation space, including specifically in obesity and diabetes (but not exclusively) and then look forward to what existing advances or tools/technologies on the horizon should shape the next 10 years of research in obesity and diabetes. Three questions we have considered when thinking about putting together this program are:

1. What have we done?
2. What are we missing?
3. What can we do moving forward?

Registration Deadline

April 10, 2019

Agenda

Tuesday, April 16, 2019

7:30 – 8:00 a.m.

Registration

8:00 – 8:10 a.m.

Meeting Introductions
Griffin P. Rodgers, M.D., MACP Director, National Institutes of Diabetes and Digestive and Kidney Diseases (NIDDK)

8:10 – 8:20 a.m.

Meeting Logistics
Luke Stoeckel, Ph.D., NIDDK

Session I: Setting the Stage

8:20 – 9:10 a.m.

The Omnivore’s Predicament: Body Weight Regulation and Cognitive Control
Alain Dagher, M.D., McGill University

9:10 – 10:00 a.m.

Habenular Regulation of Obesity-Associated Abnormalities in Food Preference and Motivation
Paul Kenny, Ph.D., Icahn School of Medicine at Mount Sinai

Session II: Imaging Circuits Involved in Food Intake and Metabolic Function

10:00 – 10:25 a.m.

D2 or Not D2, That is the Question
Dana Small, Ph.D., Yale University

10:25 – 10:50 a.m.

Neural Vulnerability Factors that Predict Future Weight Gain: Prospective Support for The Dynamic Vulnerability Model of Obesity
Eric Stice, Ph.D., Oregon Research Institute

10:50 – 11:05 a.m.

Break

Session III: Imaging Circuits Involved in Food Intake and Metabolic Function

11:05 – 11:30 a.m.

Why did I Eat That? Differences in Striatal Function and Cue-Triggered Motivation that Contribute to Obesity
Carrie Ferrario, Ph.D., University of Michigan

11:30 – 11:55 a.m.

Characterization of the Parasubthalamic Nucleus as an Appetite Suppression Center
Matt Carter, Ph.D., Williams College

11:55 a.m. – 1:45 p.m.

Lunch and Poster Session

1:45 – 2:40 p.m.

Grand Views and Potholes on the Road to Precision Neuroimaging
Moderator: Alex Martin
Russ Poldrack, Ph.D., Stanford University (presenting remotely)

Session IV: Modulation Approaches with Potential for Obesity and Diabetes

2:40 – 3:05 p.m.

Fiber-Based and Nanomagnetic Tools to Study Neural Function
Polina Anikeeva, Ph.D., Massachusetts Institute of Technology

3:05 – 3:30 p.m.

Noninvasive Neuromodulation in Obesity: What Have we Learnt and Where are we Going
Miguel Alonso-Alonso, M.D., Ph.D., Harvard Medical School

3:30 – 3:55 p.m.

Mouse to Human Translation to Optimize Safety and Success of a First-In-Human Trial of Closed-Loop Deep Brain Stimulation for Loss of Control Eating in Obesity
Casey Halpern, M.D., Stanford University

3:55 – 4:25 p.m.

General Discussion

4:25 p.m.

Recess

Wednesday, April 17, 2019

8:00 – 8:10 a.m.

Logistics
Luke Stoeckel, Ph.D., NIDDK

8:10 – 9:00 a.m.

The Neurobiology of Homeostasis
Zack Knight, Ph.D., University of California, San Francisco, Howard Hughes Medical Institute

Session V: Imaging Brain-Peripheral Tissue Interactions (Including Gut-Brain Axis)

9:00 – 9:25 a.m.

Visceral Control of Brain Reward Systems
Ivan de Araujo, Ph.D., Icahn School of Medicine at Mount Sinai

9:25 – 9:50 a.m.

Investigating the Neural Circuits Regulating Glucose Metabolism
Sarah Stanley, M.B.B.Ch., Ph.D., Icahn School of Medicine at Mount Sinai

Session VI: Mechanisms of Neurocognitive Dysfunction in Obesity and Diabetes

9:50 – 10:15 a.m.

Current Evidence for Hypothalamic Gliosis in Human Obesity and Diabetes
Ellen Schur, M.D., M.S., University of Washington School of Medicine

10:15 – 10:40 a.m.

Western Diet Consumption and Memory Impairment: What, When, and How?
Scott Kanoski, Ph.D., University of Southern California

10:40 – 11:05 a.m.

Visceral Adipose NLRP3 Impairs Cognition in Obesity by Activating Microglial IL1R1
Alexis Stranahan, Ph.D., Medical College of Georgia, Augusta University

11:05 – 11:15 a.m.

Break

Session VII: Developmental Considerations in Obesity and Diabetes

11:15 – 11:40 a.m.

Pre and Post-Natal Influences on Infant Brain and Physical Development
Sean Deoni, Ph.D., Brown University

11:40 a.m. – 12:05 p.m.

Brain Imaging Studies of Appetite in Children
Susan Carnell, Ph.D., Johns Hopkins University School of Medicine

12:05 – 12:30 p.m.

Neural Mechanisms Involved in Developmental Programming for Obesity and Diabetes
Katie Page, M.D., University of Southern California

12:30 – 12:45 p.m.

General Discussion and Closing Remarks

12:45 p.m.

Meeting Adjournment

12:45 – 2:00 p.m.

Organizing Committee Meeting

2:00 p.m.

Organizing Committee Meeting Adjournment

Abstracts

Abstract submission to present posters at the meeting is open to researchers at all levels. Interested researchers are encouraged to participate in the meeting as a poster presenter, but given limited poster space, not all submissions may be selected to present.

Submission Deadline

February 22nd, 2019 by 5:00 P.M. local time of the applicant organization

Submitting Abstracts

All abstracts must be submitted via email to Dr. Luke E. Stoeckel. Notification of those selected to present and receive travel awards will be sent by April 1st, 2019. Poster presentation details will be sent to those selected to present at that time.

Formatting Requirements

The abstract should include the following information: title, author list, and author institutional affiliations; objective(s) of the study; and methods, results, and conclusions sections. Abstracts are limited to 250 words.