Imaging the Pancreas in Diabetes, and Benign and Malignant Exocrine Pancreatic Disease
You may also be interested in the Benign and Malignant Exocrine Pancreatic Disease and the Strategies for Clinical Imaging in Diabetes meeting.
There are a large number of questions that are arising from clinical experience in the exocrine pancreas field that impact issues of diabetes pathogenesis, and vice versa—the observation of substantial changes in exocrine size and likely architecture that precede diabetes onset is one striking example of this. Other examples include inflammation and changes in organ blood flow, and the incidence of diabetes (both T1D and T2D) with exocrine diseases of various sorts. Treatment of a disease with an endocrine or exocrine pathogenesis can affect the function (good and bad) of the entire pancreas. It has become clear that while the endocrine and exocrine pancreas are studied by different communities, and the diseases are treated by people in different medical disciplines, there is a great deal to be learned at the intersection. Imaging of the pancreas is at that intersection. Many of the goals for imaging in the pancreas are similar for endocrinologists and pancreatologists, and include size, architecture and tissue physical properties such as stiffness, vasculature, nerves, inflammation, fibrosis and fat deposition. Even imaging goals specific to different disciplines, such as the goals to image islet and beta cell mass and function or to visualize tumors, can yield information that is likely to inform both communities of scientists and clinicians.
The goal of this symposium is to showcase the use of imaging in the pancreas to detect and explore the pathogenesis of diabetes, pancreatic cancers, pancreatitis and other pancreatic diseases, in humans and model systems. The emphasis is on observations and biology from the fields of diabetes and pancreas disease research that can potentially inform each other.
Gary Cline, Yale University
Martin Gotthardt, Radboud University Nijmegen, Netherlands
Paul E. Harris, Columbia University
Anna Moore, Michigan State University
Alvin Powers, Vanderbilt University
Dana Anderson, NIDDK, NIH
Olivier Blondel, NIDDK, NIH
Maren R. Laughlin, NIDDK, NIH
Lalitha Shankar, NCI, NIH
January 5, 2020