Showing filtered results. Clear filters.
Oct 27, 2016
NIH researchers unveil new wound-healing role for protein-folding gene in mice
National Institutes of Health researchers have identified a novel role for a gene known as heat shock protein 60 (Hsp60), finding that it is critical in tissue regeneration and wound healing. The study found that topical treatment of an Hsp60-containing gel dramatically accelerates wound closure in a diabetic mouse model.
Oct 14, 2016
Weight loss leads to strong increase in appetite
Analysis of a trial that used the drug canagliflozin found that as people lost weight, their appetite increased proportionately, leading to consumption of more calories and weight loss plateau (leveling off). The findings provide the first measurement in people of how strongly appetite counters weight loss as part of the body’s feedback control system regulating weight. Results are currently available on BioRxiv (link is external) and will publish in Obesity during Obesity Week 2016.
Oct 11, 2016
NIH task force formed to develop first nutrition strategic plan
The National Institutes of Health Nutrition Research Task Force (NRTF) was established to coordinate and accelerate progress in nutrition research across the NIH and guide the development of the first NIH-wide strategic plan for nutrition research for the next 10 years.
Jul 27, 2016
New medication shows promise against liver fibrosis in animal studies
A new drug developed by scientists at the National Institutes of Health limits the progression of liver fibrosis in mice, a hopeful advance against a condition for which there is no current treatment and that often leads to serious liver disease in people with chronic alcoholism and other common diseases.
Apr 18, 2016
Islet transplantation restores blood sugar awareness and control in type 1 diabetes
New clinical trial results show that transplantation of pancreatic islets — cell clusters that contain insulin-producing cells—prevents severe, potentially life-threatening drops in blood sugar in people with type 1 diabetes. Researchers found that the treatment was effective for people who experienced episodes of severe hypoglycemia — low blood sugar levels that can lead to seizures, loss of consciousness and death — despite receiving expert care.
Mar 29, 2016
Children with Cushing syndrome may have higher suicide risk
Children with Cushing syndrome may be at higher risk for suicide as well as for depression, anxiety and other mental health conditions long after their disease has been successfully treated, according to a study by researchers at the National Institutes of Health.
Mar 10, 2016
This National Kidney Month, help your children adopt healthy habits
During National Kidney Month — and World Kidney Day — the National Institutes of Health encourages you to think about how to protect your children’s kidneys, for today and for a lifetime. While most children with kidney disease were born with urinary tract problems or inherited diseases that put them at risk, some develop kidney disease as they age due to growing problems of young people, such as type 2 diabetes and high blood pressure.
Mar 4, 2016
Nutrition Roadmap Aims to Advance Research to Provide More Individualized Advice
WASHINGTON, March 4, 2016 – Today, the Interagency Committee on Human Nutrition Research (ICHNR) released the first Nutrition Research Roadmap designed to guide federal nutrition research. The 2016-2021 National Nutrition Research Roadmap encourages an increased focus on research that can lead to more individualized advice for promoting health and preventing disease.
Mar 1, 2016
Christopher J. Lynch to direct Office of Nutrition Research
Christopher J. Lynch, Ph.D., has been named the new director of the Office of Nutrition Research (ONR) and chief of the Nutrition Research Branch within the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK).
Dec 16, 2015
NIH unveils FY2016–2020 Strategic Plan
The National Institutes of Health (NIH) today released the NIH-Wide Strategic Plan, Fiscal Years 2016–2020: Turning Discovery Into Health, which will ensure the agency remains well positioned to capitalize on new opportunities for scientific exploration and address new challenges for human health.
Nov 17, 2015
Specific dosage of sickle cell drug increases survival rate
WHAT: An analysis by National Institutes of Health researchers has shown that people with sickle cell anemia who took the drug hydroxyurea at the recommended dose had higher survival rates than those who took less than the recommended dose. The findings appear in the journal PLOS ONE.
Oct 7, 2015
International diabetes research knowledge portal opens to public, scientists
Researchers funded by the National Institutes of Health and the Foundation for the NIH (FNIH) have expanded a recently launched online library, called a knowledge portal, which allows open-access searching of human genetic and clinical information on type 2 diabetes. Individual data will remain confidential.
Oct 6, 2015
NIH recruits five Lasker Clinical Research Scholars
The National Institutes of Health has selected five researchers as new Lasker Clinical Research Scholars as part of a joint initiative with the Albert and Mary Lasker Foundation to foster the next generation of great clinical scientists.
May 11, 2015
Ease of weight loss influenced by individual biology
For the first time in a lab, researchers at the National Institutes of Health found evidence supporting the commonly held belief that people with certain physiologies lose less weight than others when limiting calories.
Apr 8, 2015
Allergy drug inhibits hepatitis C in mice
An over-the-counter drug indicated to treat allergy symptoms limited hepatitis C virus activity in infected mice, according to a National Institutes of Health study.
Nov 17, 2014
Two drugs are no more effective than one to treat common kidney disease
Using two drugs was no more effective than a single drug in slowing disease progression in people with autosomal dominant polycystic kidney disease (ADPKD), according to two studies funded by the National Institutes of Health (NIH). One of the studies also showed that rigorous blood pressure treatment slowed growth of kidney cysts, a marker of ADPKD, but had little effect on kidney function compared to standard blood pressure treatment.
Nov 7, 2014
New drug for common liver disease improves liver health
An experimental drug aimed at treating a common liver disease showed promising results and potential problems in a multicenter clinical trial funded by the National Institutes of Health. The FLINT study found that people with nonalcoholic steatohepatitis (NASH) who took obeticholic acid (OCA) had improved liver health during that period, including decreased inflammation and fat in the liver and decreased body weight versus people receiving a placebo. OCA was also associated with increases in itching and total cholesterol.
Nov 3, 2014
This National Diabetes Month, take steps to improve diabetes outcomes
More than 29 million Americans have diabetes, and about 86 million more are on the verge of the disease. People with diabetes are nearly two times more likely than people without diabetes to die from heart disease, and are also at greater risk for kidney, eye and nerve diseases, among other painful and costly complications.
Oct 9, 2014
NIH invests almost $32 million to increase utility of biomedical research data
Wide-ranging National Institutes of Health grants announced today will develop new strategies to analyze and leverage the explosion of increasingly complex biomedical data sets, often referred to as Big Data. These NIH multi-institute awards constitute an initial investment of nearly $32 million in fiscal year 2014 by NIH's Big Data to Knowledge (BD2K) initiative.