U.S. Department of Health and Human Services

Clinical Research Section

T. Jake Liang, M.D., Chief

Section Staff

Senior Staff


Photo of T. Jake Liang, M.D. 

T. Jake Liang, M.D., Chief, Liver Diseases Branch

M.D. – Harvard Medical School, Boston, MA
Internal Medicine Residency – New York University/Bellevue Hospital Center, New York, NY
Gastroenterology Fellowship – Massachusetts General Hospital, Boston, MA

Photo of Edward Doo, M.D.Edward Doo, M.D., Director, Liver Diseases Research Program

M.D. – Cornell University Medical College, New York, NY
Internal Medicine Residency – The New York Hospital-Cornell Medical Center, New York, NY

 

Photo of Marc Ghany, M.D.

Marc Ghany, M.D., Tenure Track Clinical Investigator, Liver Diseases Branch

M.D. – Royal College of Surgeons in Ireland, Dublin, Ireland
Internal Medicine Residency – Hospital of St. Raphael, New Haven, CT
Gastroenterology Fellowship – Tulane University School of Medicine, New Orleans, LA
Liver Diseases Fellowship – NIDDK, Bethesda, MD
M.H.Sc. – Duke University School of Medicine, Durham, NC

Photo of Theo Heller, M.D.

Theo Heller, M.D., Tenured Clinical Investigator, Liver Diseases Branch

M.D. – University of Witwatersrand Medical school
Internal Medicine Residency – Georgetown University Hospital
Viral Hepatitis Fellowship – NIAID, Bethesda, MD
Gastroenterology Fellowship – University of Maryland School of Medicine
Liver Diseases Fellowship – NIDDK, Bethesda, MD

Photo of Jay Hoofnagle, M.D.

Jay ​Hoofnagle, M.D., Director, Liver Disease Research Branch

M.D. – Yale University School of Medicine, New Haven, CT
Internal Medicine Residency – University of Virginia Health System, Charlottesville, VA
Internal Medicine Residency – VA Medical Center, Washington, DC
Gastroenterology Fellowship – VA Medical Center, Washington, DC

nih_kohchris_Koh.jpgChristopher Koh, M.D. M.H.Sc., Staff Clinician, Liver Diseases Branch

M.D. – Saba University School of Medicine, Netherlands-Antilles
M.H.Sc. - Duke University School of Medicine, Durham, NC
Internal Medicine Residency – Harbor Hospital, Baltimore, MD
Liver Diseases Fellowship – NIDDK, Bethesda, MD
Gastroenterology Fellowship – University of Maryland/NIH Scholars Program, Baltimore, MD & Bethesda, MD

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Yaron Rotman, M.D., Tenure Track Clinical Investigator, Liver Diseases Branch

M.D. – Hebrew University Hadassah Medical School, Jerusalem, Israel
M.Sc. – Hebrew University Hadassah Medical School, Jerusalem, Israel
Internal Medicine Residency – Rabin Medical Center, Petach-Tiqwa, Israel
Gastroenterology Fellowship – Rabin Medical Center, Petach-Tiqwa, Israel
Liver Diseases Fellowship – NIDDK, Bethesda, MD

Photo Not Available

Averell H. Sherker, M.D., Scientific Advisor, Viral Hepatitis and Liver Diseases

M.D. – Queens University Faculty of Health Sciences, Kingston, Canada
Internal Medicine Residency – Mt. Sinai Hosptial University, Toronto, Canada
Gastroenterology Fellowship – University of Toronto, Ontario, Canada
Liver Diseases Fellowship – Stanford University, Stanford, CA

Clinical Hepatology Fellows

Gil Ben-Yakov

Gil Ben-Yakov, M.D., Clinical Fellow

M.D. - Ben-Gurion University, Faculty of Health Sciences, Israel
Internal Medicine Residency - Soroka University Medical Center, Israel
Gastroenterology/Hepatology Fellowship - Soroka University Medical Center, Israel

Primary sclerosing cholangitis (PSC) is a rare, chronic cholestatic liver and biliary tract disease, with a highly variable clinical presentation and natural history. The pathogenesis of PSC remains elusive, nevertheless, cumulative evidence suggests its development is immune-mediated and follows an immune priming event in genetically pre-disposed individuals.

The intricate relationships and interactions between host genetics, immune responses, behavioral and environmental triggers underlying the pathogenesis of PSC have not yet been elucidated. My main research interest is to identify those interactions and their role in the development of PSC.

Other research interests of mine include, liver manifestations in syndromes of immune disregulation and understanding the differential metabolic pathways dominating in post prandial state in NAFLD patients versus healthy controls.

Devika Kapuria

Devika Kapuria, M.D., Clinical Fellow

M.D. - Lady Hardinge Medical College, New Dehli, India
Internal Medicine Residency - University of Missouri, Kansas City, MO

Liver disease is fascinating-the liver controls a host of processes in the body ranging from the immune system to metabolism. My interests include delta hepatitis, non-cirrhotic portal hypertension and the association of fatty liver disease with abnormalities in metabolic pathways of the body. The recent advent of novel viral prenylation inhibitors for delta hepatitis is a rapidly developing field; NIDDK has been actively involved in phase 2 studies that show promising results.

Non-cirrhotic portal hypertension is a diverse group of disorders with widely varying causes and outcomes, there has been no treatment identified to modify the natural history of the disease-perhaps given the heterogeneity. My clinical focus is to work on the characterization of the natural history of non-cirrhotic portal hypertension.

I am also interested in the physiologic and metabolic pathways connecting the liver and the cardiovascular system, how changes in one can affect the other.

Ahmed S. Alawad

Ahmed S. Alawad, M.D., Clinical Fellow

M.D. - University of Aleppo, Aleppo, Syria
Internal Medicine Residency - Medstar Franklin Square Medical Center, Baltimore, MD

Fatty liver disease currently affects one third of the United States population and it is projected to become number one cause for liver transplant in 2020. Despite the tremendous advancement in different fields of hepatology, we still have a lot to investigate in the pathogenesis of fatty liver disease and finding treatment for the disease. My primary interest is in evaluating new treatment methods for fatty liver disease, and finding non-invasive methods the could estimate accurately the severity of the disease.


Varun TEtzion Ohad, Clinical Fellowakyar, M.D., Clinical Fellow

M.D. - Ross University School of Medicine, Dominica, West Indies
Internal Medicine Residency - University of Arizona, Tucson, Arizona

I came to NIDDK from University of Arizona in Tucson.  The Liver Diseases Branch gives me a unique opportunity to attempt to answer challenging questions about hepatic parenchymal pathology.  In recent years, macrophages have garnered much attention in hepatic fibrogenesis and its subsequent resolution.  However, a lot of questions are left answered regarding the role of our immune system in hepatic inflammation and scar formation. My main scientific research focus is looking at microbial and intrinsic triggers of inflammation and fibrosis in chronic liver disease.  Additionally, my clinical research interest is in using non-invasive techniques to identify stage of hepatic fibrosis in chronic liver disease and to identify the degree of portal hypertension in cirrhosis.

Clinical Specialists


Shelley Anne Ganio, Patient Care Coordinator

 

10 Center Drive, Bldg: 10 CRC, Rm: 4-5722, MSC 16142
T: 301-435-6121
F: 301-435-9160


Nancy Fryzek, BSN, RN, MBA, Clinical Nurse Manager, Research Nurse, Specialist
 

10 Center Drive, Bldg: 10 CRC, Rm: 4-5722, MSC 1614
Bethesda, MD 20892
T: 301-435-6122
F: 301-435-9160


Vanessa Haynes-Williams, BSN, RN, Research Nurse, Specialist

 

10 Center Drive, Bldg: 10 CRC, Rm: 4-5722, MSC 1614
Bethesda, MD 20892
T: 301-451-7007
F: 301-435-9160


Elenita M. Rivera, BSN, RN, Research Nurse, Specialist

 

10 Center Drive, Bldg: 10 CRC, Rm: 4-5722, MSC 1614
Bethesda, MD 20892
T: 301-435-6125
F: 301-451-9160


Amy Huang, BSN, BS, BA, RN, Research Nurse, Specialist

 

10 Center Drive, Bldg: 10 CRC, Rm: 4-5722, MSC 1614
Bethesda, MD 20892
T: 301-451-6983
F: 301-435-9160​