U.S. Department of Health and Human Services

Molecular Medicine Branch

Alan Neil Schechter, M.D., Chief

​Research Images

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Hypothalamus expression of erythropoietin receptorErythropoietin receptor (EpoR) co-localizes to proopiomelanocortin (POMC), producing neurons in the hypothalamus that regulate food intake and energy expenditure.Hypothalamus expression of erythropoietin receptorEnlarge
Multi-tissue response to erythropoietinErythropoietin regulates oxygen delivery through red blood cell production. In model systems it stimulates other select tissues to affect oxygen consumption and metabolic response.Multi-tissue response to erythropoietinEnlarge
Erythropoietin receptor expression in neural cellsErythropoietin receptor (EpoR) is expressed on neural progenitor cells and neurons.Erythropoietin receptor expression in neural cellsEnlarge
Erythropoietin stimulates red blood cell productionErythropoietin (EPO) is produced in the kidney, regulates the daily production of 200 billion red blood cells, and is inducible by low oxygen or hypoxia.Erythropoietin stimulates red blood cell productionEnlarge
Imaging White Fat in MiceWhole body image of fat in normal wild type mice (WT) and obese mice with erythropoietin receptor restricted to erythroid cells (EpoR).Imaging White Fat in MiceEnlarge