U.S. Department of Health and Human Services

Kidney Disease Section

Jeffrey B. Kopp, M.D., Chief


Patents, materials, and other research resources appear below. Some resources may be available for use through Material Transfer Agreements (MTAs) or licensing agreements.

Resource Name Description
Podocin-rtTA (Tg(NPHS2-rtTA2*M2)1Jbk Mouse (Mutant Mouse: The tet transactivator (rtTA) gene placed under the control of the human NPHS2 gene).)

Reverse tetracycline-controlled transgenic mouse model (Tet-On) under the control of the specific promoter for the glomerular podocyte protein (Podocin, NPHS2).

Podocytes are post-mitotic epithelial cells that are positioned on the exterior aspect of…

Inducible podocyte-specific gene expression in transgenic mice (Podocin/rtTA DNA transgene)

The podocyte plays a key role in glomerular function and glomerular disease. To facilitate studies of podocyte function, we have developed a transgenic mouse model with inducible expression in the podocyte. The tetracycline-inducible transgenic…

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Clinical Trials

Open studies conducted by NIDDK Principal Investigators appear below that are currently recruiting, not yet recruiting, or available for expanded access.