U.S. Department of Health and Human Services

Renal Diagnostics and Therapeutics Unit

Robert A. Star, M.D., Chief


A selection of recent and significant publications can be viewed below.

Street JM, Yuen PS, Star RA. Bioactive Exosomes: Possibilities for Diagnosis and Management of Bladder Cancer. J Urol. 2014 Aug; 192 (2; 2014 Aug; 192):297-8. [Full Text/Abstract]
Street JM, Souza AC, Alvarez-Prats A, Horino T, Hu X, Yuen PS, Star RA. Automated quantification of renal fibrosis with Sirius Red and polarization contrast microscopy. Physiol Rep. 2014 Jul 1; 2 (2014 Jul 1; 2; 7). [Full Text/Abstract]
Chawla LS, Eggers PW, Star RA, Kimmel PL. Acute kidney injury and chronic kidney disease as interconnected syndromes. N Engl J Med. 2014 Jul 3; 371 (1; 2014 Jul 3; 371):58-66. [Full Text/Abstract]
Bonventre JV, Basile D, Liu KD, McKay D, Molitoris BA, Nath KA, Nickolas TL, Okusa MD, Palevsky PM, Schnellmann R, Rys-Sikora K, Kimmel PL, Star RA, on behalf of the Kidney Research National Dialogue (KRND). AKI: A Path Forward. Clin J Am Soc Nephrol. 2013 Sep; 8 (8; 2013 Sep; 9):1606-8. [Full Text/Abstract]
Zhou H, Kajiyama H, Tsuji T, Hu X, Leelahavanichkul A, Vento S, Frank R, Kopp JB, Trachtman H, Star RA, Yuen PS. Urinary exosomal Wilms tumor-1 as a potential biomarker for podocyte injury. Am J Physiol Renal Physiol. 2013 Aug 15; 305 (4; 2013 Aug 15; 305):F553-9. [Full Text/Abstract]
Zafrani L, Gerotziafas G, Byrnes C, Hu X, Perez J, LĂ©vi C, Placier S, Letavernier E, Leelahavanichkul A, Haymann JP, Elalamy I, Miller JL, Star RA, Yuen PS, Baud L. Calpastatin controls polymicrobial sepsis by limiting procoagulant microparticle release. Am J Respir Crit Care Med. 2012 Apr 1; 185 (2012 Apr 1; 7; 185):744-55. [Full Text/Abstract]
Leelahavanichkul A, Bocharov AV, Kurlander R, Baranova IN, Vishnyakova TG, Souza AC, Hu X, Doi K, Vaisman B, Amar M, Sviridov D, Chen Z, Remaley AT, Csako G, Patterson AP, Yuen PS, Star RA, Eggerman TL. Class B scavenger receptor types I and II and CD36 targeting improves sepsis survival and acute outcomes in mice. J Immunol. 2012 Mar 15; 188 (2012 Mar 15; 188; 6):2749-58. [Full Text/Abstract]
Leelahavanichkul A, Huang Y, Hu X, Zhou H, Tsuji T, Chen R, Kopp JB, Schnermann J, Yuen PS, Star RA. Chronic kidney disease worsens sepsis and sepsis-induced acute kidney injury by releasing High Mobility Group Box Protein-1. Kidney Int. 2011 Dec; 80 (80; 2011 Dec; 11):1198-211. [Full Text/Abstract]
Leelahavanichkul A, Yan Q, Hu X, Eisner C, Huang Y, Chen R, Mizel D, Zhou H, Wright EC, Kopp JB, Schnermann J, Yuen PS, Star RA. Angiotensin II overcomes strain-dependent resistance of rapid CKD progression in a new remnant kidney mouse model. Kidney Int. 2010 Dec; 78 (2010 Dec; 78; 11):1136-53. [Full Text/Abstract]
Doi K, Leelahavanichkul A, Yuen PS, Star RA. Animal models of sepsis and sepsis-induced kidney injury. J Clin Invest. 2009 Oct; 119 (2009 Oct; 119; 10):2868-78. [Full Text/Abstract]
Doi K, Leelahavanichkul A, Hu X, Sidransky KL, Zhou H, Qin Y, Eisner C, Schnermann J, Yuen PS, Star RA. Pre-existing renal disease promotes sepsis-induced acute kidney injury and worsens outcome. Kidney Int. 2008 Oct; 74 (74; 8; 2008 Oct):1017-25. [Full Text/Abstract]
Zhou H, Cheruvanky A, Hu X, Matsumoto T, Hiramatsu N, Cho ME, Berger A, Leelahavanichkul A, Doi K, Chawla LS, Illei GG, Kopp JB, Balow JE, Austin HA 3rd, Yuen PS, Star RA. Urinary exosomal transcription factors, a new class of biomarkers for renal disease. Kidney Int. 2008 Sep; 74 (74; 5; 2008 Sep):613-21. [Full Text/Abstract]
Kobayashi H, Jo SK, Kawamoto S, Yasuda H, Hu X, Knopp MV, Brechbiel MW, Choyke PL, Star RA. Polyamine dendrimer-based MRI contrast agents for functional kidney imaging to diagnose acute renal failure. J Magn Reson Imaging. 2004 Sep; 20 (20; 3; 2004 Sep):512-8. [Full Text/Abstract]
Yuen PS, Dunn SR, Miyaji T, Yasuda H, Sharma K, Star RA. A simplified method for HPLC determination of creatinine in mouse serum. Am J Physiol Renal Physiol. 2004 Jun; 286 (2004 Jun; 6; 286):F1116-9. [Full Text/Abstract]
Miyaji T, Hu X, Yuen PS, Muramatsu Y, Iyer S, Hewitt SM, Star RA. Ethyl pyruvate decreases sepsis-induced acute renal failure and multiple organ damage in aged mice. Kidney Int. 2003 Nov; 64 (2003 Nov; 64; 5):1620-31. [Full Text/Abstract]
Jo SK, Hu X, Kobayashi H, Lizak M, Miyaji T, Koretsky A, Star RA. Detection of inflammation following renal ischemia by magnetic resonance imaging. Kidney Int. 2003 Jul; 64 (64; 2003 Jul; 1):43-51. [Full Text/Abstract]
Miyaji T, Hu X, Star RA. alpha-Melanocyte-simulating hormone and interleukin-10 do not protect the kidney against mercuric chloride-induced injury. Am J Physiol Renal Physiol. 2002 May; 282 (2002 May; 282; 5):F795-801. [Full Text/Abstract]