NIDDK’s Hepatology Fellowship Program has a long tradition of training fellows worldwide for a career in academic hepatology. This program has made seminal contributions to both basic and clinical research in the field of liver diseases. Under the leadership of Dr. T. Jake Liang, Chief of the Liver Diseases Branch, the program has a strong commitment to providing excellent training to its fellows to develop the necessary skills to become independent physician-scientists in the field of hepatology. Many graduates from this program are, or have been, leaders in academic centers and national organizations.
Basic research projects range from molecular pathogenesis of hepatitis B and C, mechanisms of actions of interferons, viral kinetics, antiviral and HCV vaccine development, noncirrhotic portal hypertension, and iron metabolism to immunological responses in viral hepatitis and autoimmune hepatitis. Clinical research protocols are equally diverse and are ever-expanding from studies of the natural history to treatment trials of HCV, HBV, HDV, nonalcoholic steatohepatitis, noncirrhotic portal hypertension, primary biliary cirrhosis and autoimmune hepatitis. The program also supports the opportunity for earning a concomitant Master's Degree in Clinical Research.
The program is offered for a period of 2-5 years depending upon the applicant’s career goals and research projects. Each year 1-2 positions are offered to eligible candidates depending upon the number of vacancies in that particular year.
Consultative and Inpatient Service
During the first year of training, fellows manage the hepatology consult and inpatient service for approximately four months each. In subsequent years, fellows manage the service for approximately two months per year. Consultations and inpatient management services occur on a daily basis under the close supervision of a full-time faculty member. Fellows may supervise medical residents and/or students doing a hepatology subspecialty rotation. The consultation service includes didactic teaching, bedside evaluation of patients on work rounds, and participation in weekly hepatology clinical rounds. Patients admitted to the hepatology inpatient service are primarily for protocol-driven liver biopsies and viral kinetic studies.
The Hepatology Clinic operates on Monday, Wednesday, and Friday from 8:30 am to 12:00 pm. Under faculty supervision, fellows will follow their own patients and develop skills in evaluating and managing patients with liver disease. Additionally, fellows will learn to manage patients that are participating in ongoing clinical trials in the Liver Diseases Branch.
Courses and Rounds
The NIDDK Hepatology Fellowship Program supports the opportunity for enrolling in courses towards a concomitant Master's Degree in Clinical Research, which is a collaborative program between the NIH Clinical Center and Duke University Medical Center.
The Liver Diseases Branch weekly rounds schedule includes:
- Work Rounds and Hepatology Didactic Session: Mondays, 12:00 pm – 1:30 pm
- Clinical Hepatology Rounds: Thursdays, 8:30 am – 10:00 am
- Liver Pathology Rounds: Thursdays, 3:45 pm – 4:45 pm
- Liver Diseases Branch Lab Meeting: Fridays, 1:30 pm – 2:30 pm
- Gastrointestinal/Hepatology Radiology Rounds: First Friday of every month, 12:30 pm – 1:30 pm
Faculty and Fellows