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Resources for Clinical Researchers

The following resources are available for clinical researchers in NIDDK-funded studies.

NIDDK Central Repository

The NIDDK Central Repository provides data and biosamples collected from current and previously funded NIDDK studies to the scientific community. This enables scientists who were not involved in an original study to test new hypotheses without collecting new data or biospecimens and provides the opportunity to pool data across several studies to increase the power of statistical analyses. In addition, many NIDDK-funded studies collect genetic biospecimens and carry out high-throughput genotyping, making it possible for other scientists to use Repository resources to match genotypes to phenotypes and to perform informative genetic analyses.

The Repository has three contract-funded components that work together to store data and samples:

  • Biosample Repository – gathers, stores, and distributes biological samples
  • Genetics Repository – receives and processes blood samples, generally from pediatric study participants, to allow genetic analyses; creates immortalized cell lines or cryopreserves nucleate cells for future immortalization; and prepares DNA from whole blood, cryopreserved cells and cell lines
  • Database Repository – gathers, stores and distributes the incremental or finished datasets from studies

The NIDDK invites investigators to apply for access to data and samples on the NIDDK Central Repository website. NIDDK also provides funding opportunities to support data sample requests and research.

Frequently asked questions about the NIDDK Central Repository are available on the Repository’s website.

Research Centers

NIDDK provides support for disease-oriented research at institutions that have an existing base of high quality research. Centers foster interdisciplinary work, provide core services, and offer funding for pilot and feasibility studies that use the core resources. View the individual centers pages below for more information and to contact NIDDK program directors.

NIDDK Information Network (dkNET)

NIDDK Information Network (dkNET) provides simultaneous search of digital resources, including multiple datasets and biomedical resources relevant to the mission of the NIDDK.

NIDDK Research Resources

NIDDK compiles a list of Research Resources (reagents, data, protocols, etc.) have been derived from publically available information provided by NIDDK-funded investigators, projects, and publications.

Some entries available in Research Resources are duplicated in the NIDDK Central Repository and NIDDK Information Network (dkNET) databases.