U.S. Department of Health and Human Services

Clinical, Behavioral, and Epidemiological Obesity Research

The Clinical, Behavioral, and Epidemiological Obesity Research program supports clinical, behavioral, and epidemiological research focused on improved understanding of the development and modulation of obesity.

This research program includes clinical and behavioral studies in humans examining topics such as, but not limited to, identifying and understanding risk factors for the development and/or maintenance of excess weight gain, including basic behavioral, psychological, and social mechanisms and variation in dietary intake, dietary composition, meal frequency, eating patterns, sedentary behavior, and physical activity.  In addition, this program also supports research to understand metabolic effects and co-morbidities associated with obesity.  Studies across the lifespan, in various weight categories, and in high-risk populations are of interest.

The program supports the collection, analysis, and dissemination of data on obesity, weight status, weight control throughout the lifespan, and obesity-related disorders of public health significance, with particular emphasis on surveillance and follow-up studies.  Correlation and association analyses of risk factors for overweight/obesity—including environmental, psychological, social, economic—and secondary data analyses using data from a variety of sources, such as nationally representative, regional, or locally based data sets, are also supported.
Other relevant research projects would include methodologies to improve assessment of dietary intake and energy expenditure; i.e., sedentary behavior and physical activity, in humans.
The Clinical, Behavioral, and Epidemiological Obesity Research program does not support research to test nutrition or obesity prevention and treatment approaches.  For obesity prevention and treatment research, please see the Obesity Treatment and Prevention Program.  For clinical nutrition research, please see Clinical and Epidemiological Nutrition Research.

 NIDDK Staff

Mary Evans, Ph.D.Multi-center Clinical Studies in Nutrition & Obesity; Nutrition Obesity Research Centers; Diet & Physical Activity Assessment MethodologyChristine Hunter, Ph.D., ABPPBehavioral research on the prevention and treatment of obesity and diabetes; Centers for Diabetes Translational ResearchRobert Kuczmarski, Dr.P.H.Obesity Treatment and Prevention
Padma Maruvada, Ph.D.Nutrient Metabolism; Clinical Obesity and NutritionAynur Unalp-Arida M.D., M.Sc., Ph.D.Epidemiology, Clinical Trials, Digestive Diseases, and Nutrition


 Related Funding Opportunities

Posted DateTitleFull Announcement
2/1/2017Development of Highly Innovative Tools and Technology for Analysis of Single Cells (STTR) (R41/R42) (Summary) PA-17-148
2/1/2017Development of Highly Innovative Tools and Technology for Analysis of Single Cells (SBIR) (R43/R44) (Summary) PA-17-147
1/24/2017Lead Optimization and Preclinical Development of Therapeutic Candidates for Diseases of Interest to the NIDDK (R43/R44) (Summary) PA-17-130
1/24/2017Lead Optimization and Preclinical Development of Therapeutic Candidates for Diseases of Interest to the NIDDK (R41/R42) (Summary) PA-17-131
1/17/2017Biomarkers for Diabetes, Digestive, Kidney and Urologic Diseases Using Biosamples from the NIDDK Repository (R01) (Summary) PAR-17-123
View More Funding Opportunities

The resources listed below include reagents, data, protocols, etc. If you would like to utilize any of these resources, contact the person associated with the resource.


 Research Resources

Resource NameDescription
Mouse Metabolic Phenotyping Centers

The MMPC is a National Institutes of Health-sponsored resource that provides experimental testing services to scientists studying diabetes, obesity, diabetic complications, and other metabolic diseases in mice.

Acute Liver Failure Study Group
The Acute Liver Failure Study Group is collecting biosamples and information on the natural history, causes and outcomes of Acute Liver Failure in the United States. In addition to the database, a clinical trial conducted to test whether the drug…
Evaluating Predictors and Interventions in Sphincter of Oddi Dysfunction

The EPISOD study is a prospective, double-blind, randomized, sham-controlled, multi-center clinical trial. The EPISOD study enrolls subjects who have received a prior cholecystectomy and are diagnosed with the clinical syndrome of Sphincter of Oddi…

Integrated Islet Distribution Program

The goal of the Integrated Islet Distribution Program (IIDP) is to work with the leading islet isolation centers in the U.S. to distribute high quality human islets to the diabetes research community, in order to advance scientific discoveries and…

Efficacy and Mechanisms of Glutamine Dipeptide in the Surgical Intensive Care Unit

The GLND trial is a multi-center, double-blind, placebo-controlled, intent-to-treat Phase III trial, designed to determine the effect of parenteral glutamine (GLN) dipeptide on important clinical outcomes in patients requiring surgical intensive care…

View Additional Research Resources


 NIDDK Active Trials in Obesity

View related clinical trials from ClinicalTrials.gov.


 Related Study Sections

Study sections conduct initial peer review of applications in a designated scientific area. View related study sections from the NIH's Center for Scientific Review.​