U.S. Department of Health and Human Services

Acute Kidney Injury

The Acute Kidney Injury (AKI) program supports basic, translational, and clinical studies on pathogenesis, prevention, and treatment.  Fundamental research addresses renal cell response to acute injury or toxic exposure, renal vascular alterations, and mechanisms involved in repair and regeneration.  The portfolio aims to develop functional, structural, and imaging markers for diagnosis, early detection, severity, prognosis, and outcomes.  Also of interest is research on the natural history of AKI, including studies on risk and outcome stratification, for early stages and progression to chronic kidney disease.​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​


 NIDDK Staff

Deborah Hoshizaki, Ph.D.Kidney and Urogenital Development; Kidney and Urology Regeneration and Repair; Urology CentersPaul L. Kimmel, M.D.Clinical AKI; Kidney Translational Genetics; Kidney Centers; Kidney HIV/AIDS
Krystyna Rys-Sikora, Ph.D.AKI and CKD Pathobiology


 Related Funding Opportunities

Posted DateTitleFull Announcement
10/19/2016Addressing Health Disparities in NIDDK Diseases (R01) (Summary) PA-17-021
10/7/2016BD2K Support for Meetings of Data Science Related Organizations (U13) (Summary) RFA-CA-16-020
9/28/2016Kidney Precision Medicine Project - Technology Development and Validation (R41/R42) (Summary) PA-16-451
9/28/2016Kidney Precision Medicine Project - Technology Development and Validation (R43/R44) (Summary) PA-16-452
8/24/2016Big Data to Knowledge (BD2K) Enhancing the Efficiency and Effectiveness of Digital Curation for Biomedical Big Data (U01) (Summary) RFA-LM-17-001
View More Funding Opportunities

The resources listed below include reagents, data, protocols, etc. If you would like to utilize any of these resources, contact the person associated with the resource.


 Research Resources

Resource NameDescription
Action to Control Cardiovascular Disease Risk in Diabetes Follow-up Study
ACCORDION (sponsored by NHLBI) is a prospective, observational follow-up study of at least 8000 participants who were treated and followed in the Action to Control Cardiovascular Risk in Diabetes (ACCORD) Trial.  Treatment in ACCORD ended in 2009 and…
Diabetic Complications Consortium
The goal of the NIDDK-sponsored Diabetic Complications Consortium (DiaComp) is to foster communication and collaboration between investigator communities involved in complications research.  Toward this goal, DiaComp: (1) sponsors annual meetings in…
Rare Kidney Stone Consortium

The Consortium facilitates cooperative exchange of information and resources among investigators, clinicians, patients, and researchers in order to improve care and outcomes for patients with rare stone diseases.  The consortium promotes ready…

Randomized Intervention for Children with Vesicoureteral Reflux

The purpose of this study is to learn whether all children with vesicoureteral reflux (VUR) should be treated with antibiotics. The study will tell us if prophylactic antibiotic treatment prevents urinary tract infections and renal scarring in…

United States Renal Data System

The United States Renal Data System (USRDS) is a national data system that collects, analyzes, and distributes information about end-stage renal disease (ESRD) in the United States. The USRDS is funded directly by the National Institute of Diabetes…

View Additional Research Resources


 NIDDK Active Trials in Acute Kidney Injury

View related clinical trials from ClinicalTrials.gov.


 Related Study Sections

Study sections conduct initial peer review of applications in a designated scientific area. View related study sections from the NIH's Center for Scientific Review.