U.S. Department of Health and Human Services

Clinical and Epidemiological Nutrition Research

The Clinical and Epidemiological Nutrition Research program supports clinical research focused on observational/interventional studies in nutrition, as well as nutritional epidemiology studies.  This program includes clinical studies examining the effects of nutrient or dietary intake, diet composition, diet intervals, variation in nutritional status, or interventions ranging from, but not limited to, whole foods/dietary patterns, dietary supplements, or alternative delivery modes (i.e., parenteral or enteral nutrition) on health-related outcomes in humans.  Nutrients may encompass macronutrients, vitamins/minerals, phytonutrients, and other food components.  Clinical studies of nutritional status or interventions from infancy throughout the aging process are of interest.  The program serves as a focal point for the collection, analysis, and dissemination of data on nutritional intake, status, and disorders of public health significance, with particular emphasis on national/global surveillance and follow-up studies.  This program also includes policy- and population-based approaches to improving nutrient/dietary intake or nutritional status not focused on obesity/weight control.  Other relevant research projects would include methodologies to improve assessment of nutrient intake and/or status in humans throughout the lifespan.
The Clinical and Epidemiological Nutrition Research program does not support research regarding obesity, energy balance, or weight control.  For obesity research, please see Obesity Treatment and Prevention or Clinical, Behavioral, and Epidemiological Obesity Research.  For research related to nutrient requirements and metabolism, see Nutrient Metabolism, Status, and Assessment.

 NIDDK Staff

Dana K. Andersen, M.D.Mary Evans, Ph.D.Multi-center Clinical Studies in Nutrition & Obesity; Nutrition Obesity Research Centers; Diet & Physical Activity Assessment Methodology
Padma Maruvada, Ph.D.Nutrient Metabolism; Clinical Obesity and NutritionAynur Unalp-Arida M.D., M.Sc., Ph.D.Epidemiology, Clinical Trials, Digestive Diseases, and Nutrition


 Related Funding Opportunities

Posted DateTitleFull Announcement
2/1/2017Development of Highly Innovative Tools and Technology for Analysis of Single Cells (STTR) (R41/R42) (Summary) PA-17-148
2/1/2017Development of Highly Innovative Tools and Technology for Analysis of Single Cells (SBIR) (R43/R44) (Summary) PA-17-147
1/24/2017Lead Optimization and Preclinical Development of Therapeutic Candidates for Diseases of Interest to the NIDDK (R43/R44) (Summary) PA-17-130
1/24/2017Lead Optimization and Preclinical Development of Therapeutic Candidates for Diseases of Interest to the NIDDK (R41/R42) (Summary) PA-17-131
1/17/2017Biomarkers for Diabetes, Digestive, Kidney and Urologic Diseases Using Biosamples from the NIDDK Repository (R01) (Summary) PAR-17-123
View More Funding Opportunities

The resources listed below include reagents, data, protocols, etc. If you would like to utilize any of these resources, contact the person associated with the resource.


 Research Resources

Resource NameDescription
Efficacy and Mechanisms of Glutamine Dipeptide in the Surgical Intensive Care Unit

The GLND trial is a multi-center, double-blind, placebo-controlled, intent-to-treat Phase III trial, designed to determine the effect of parenteral glutamine (GLN) dipeptide on important clinical outcomes in patients requiring surgical intensive care…

Action to Control Cardiovascular Disease Risk in Diabetes Follow-up Study
ACCORDION (sponsored by NHLBI) is a prospective, observational follow-up study of at least 8000 participants who were treated and followed in the Action to Control Cardiovascular Risk in Diabetes (ACCORD) Trial.  Treatment in ACCORD ended in 2009 and…
Diabetic Complications Consortium
The goal of the NIDDK-sponsored Diabetic Complications Consortium (DiaComp) is to foster communication and collaboration between investigator communities involved in complications research.  Toward this goal, DiaComp: (1) sponsors annual meetings in…
NIDDK Information Network

The NIDDK Information Network (dkNET), serves the needs of basic and clinical investigators by providing seamless access to large pools of data relevant to the mission of NIDDK. The goal of dkNET is to develop a community-based network for…

NIDDK Repository for Biosamples and Data

Supports Data, Biosample, and Genetic Repositories to increase the impact of current and previously funded NIDDK studies by making their data and biospecimens available to the broader scientific community. These Repositories enable scientists not…

View Additional Research Resources


 NIDDK Active Trials in Nutrition

View related clinical trials from ClinicalTrials.gov.


 Related Study Sections

Study sections conduct initial peer review of applications in a designated scientific area. View related study sections from the NIH's Center for Scientific Review.
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NIH Common Fund

Learn about current projects and view funding opportunities sponsored by the​ ​​NIH Common Fund.​