NIDDK’s Diabetes Centers program supports extramural research institutions that have established an existing base of high-quality, diabetes-related research. Diabetes Centers are designed to support and enhance the national research effort in diabetes, its complications, and related endocrine and metabolic diseases. The program supports and enhances interdisciplinary research in diabetes but does not directly fund major research projects; rather, it provides core resources to enhance the efficiency, productivity, and interdisciplinary cooperation of a group of established investigators conducting research in diabetes and related areas of endocrinology and metabolism.
The Centers have three primary structural components:
• Shared resources (cores)
• Pilot and feasibility studies
• Enrichment programs
Shared resources are core facilities, resources, and expertise, or other cooperative arrangements, that enhance productivity and benefit research programs by investigators working to accomplish common goals. Pilot and feasibility studies can have a major impact on the visibility of a Center and should provide a means of developing new ideas and encouraging junior investigators or investigators new to the field. The Centers also have enrichment program that advance diabetes research, promote scientific exchange among investigators with related research interests, and enhance interactions between diabetes researchers and investigators from other fields with relevant expertise.
There are two types of Diabetes Centers in the program:
The DRCs promote new discoveries and enhance scientific progress through support of cutting-edge basic and clinical research related to the etiology and complications of diabetes, with the goal of rapidly translating research findings into novel strategies for the prevention, treatment and cure of diabetes and related conditions. DRCs are intended to improve the quality and multidisciplinary nature of research on diabetes and related endocrinology and metabolism research by providing shared access to specialized technical resources and expertise and by creating an environment that supports important and innovative research. DRCs are expected to raise awareness and interest in fundamental and clinical diabetes research at their institutions, as well as locally, regionally, and nationally.
The CDTRs support and enhance type II translation research (e.g.; moving from efficacy to testing effectiveness in real world practice and communities and dissemination and implementation science) related to diabetes prevention and treatment. CDTRs are intended to enhance the efficiency, productivity, and multidisciplinary nature of diabetes translation research through shared access to specialized technical expertise and resources. CDTRs expertise includes intervention adaptation and refinement, development of measures, techniques, processes, methods, and practices related to diabetes translation research. CDTRs provide core services and consultation at their local institution but also serve as resources regionally and nationally.