U.S. Department of Health and Human Services

Diabetes Centers

NIDDK’s Diabetes Centers program supports extramural research institutions that have established an existing base of high-quality, diabetes-related research. Diabetes Centers are designed to support and enhance the national research effort in diabetes, its complications, and related endocrine and metabolic diseases.  The program supports and enhances interdisciplinary research in diabetes but does not directly fund major research projects; rather, it provides core resources to enhance the efficiency, productivity, and interdisciplinary cooperation of a group of established investigators conducting research in diabetes and related areas of endocrinology and metabolism.

The Centers have three primary structural components:
• Shared resources (cores)
• Pilot and feasibility studies
• Enrichment programs

Shared resources are core facilities, resources, and expertise, or other cooperative arrangements, that enhance productivity and benefit research programs by investigators working to accomplish common goals. Pilot and feasibility studies can have a major impact on the visibility of a Center and should provide a means of developing new ideas and encouraging junior investigators or investigators new to the field.  The Centers also have enrichment program that advance diabetes research, promote scientific exchange among investigators with related research interests, and enhance interactions between diabetes researchers and investigators from other fields with relevant expertise.

There are two types of Diabetes Centers in the program:

Diabetes Research Centers (DRCs)

The DRCs promote new discoveries and enhance scientific progress through support of cutting-edge basic and clinical research related to the etiology and complications of diabetes, with the goal of rapidly translating research findings into novel strategies for the prevention, treatment and cure of diabetes and related conditions.  DRCs are intended to improve the quality and multidisciplinary nature of research on diabetes and related endocrinology and metabolism research by providing shared access to specialized technical resources and expertise and by creating an environment that supports important and innovative research.  DRCs are expected to raise awareness and interest in fundamental and clinical diabetes research at their institutions, as well as locally, regionally, and nationally.

Centers for Diabetes Translation Research (CDTRs)

The CDTRs support and enhance type II translation research (e.g.; moving from efficacy to testing effectiveness in real world practice and communities and dissemination and implementation science) related to diabetes prevention and treatment. CDTRs are intended to enhance the efficiency, productivity, and multidisciplinary nature of diabetes translation research through shared access to specialized technical expertise and resources.  CDTRs expertise includes intervention adaptation and refinement, development of measures, techniques, processes, methods, and practices related to diabetes translation research. CDTRs provide core services and consultation at their local institution but also serve as resources regionally and nationally.

 NIDDK Staff

Christine Hunter, Ph.D., ABPPBehavioral research on the prevention and treatment of obesity and diabetes; Centers for Diabetes Translational ResearchJames F. Hyde, Ph.D.Neurobiology of energy balance and body composition in obesity; Diabetes Research Centers
Pamela Thornton, Ph.D.Health Disparities and Implementation Science


 Related Funding Opportunities

Posted DateTitleFull Announcement
2/1/2017Development of Highly Innovative Tools and Technology for Analysis of Single Cells (STTR) (R41/R42) (Summary) PA-17-148
2/1/2017Development of Highly Innovative Tools and Technology for Analysis of Single Cells (SBIR) (R43/R44) (Summary) PA-17-147
1/24/2017Lead Optimization and Preclinical Development of Therapeutic Candidates for Diseases of Interest to the NIDDK (R43/R44) (Summary) PA-17-130
1/24/2017Lead Optimization and Preclinical Development of Therapeutic Candidates for Diseases of Interest to the NIDDK (R41/R42) (Summary) PA-17-131
1/17/2017Biomarkers for Diabetes, Digestive, Kidney and Urologic Diseases Using Biosamples from the NIDDK Repository (R01) (Summary) PAR-17-123
View More Funding Opportunities

The resources listed below include reagents, data, protocols, etc. If you would like to utilize any of these resources, contact the person associated with the resource.


 Research Resources

Resource NameDescription
Mouse Metabolic Phenotyping Centers

The MMPC is a National Institutes of Health-sponsored resource that provides experimental testing services to scientists studying diabetes, obesity, diabetic complications, and other metabolic diseases in mice.

Integrated Islet Distribution Program

The goal of the Integrated Islet Distribution Program (IIDP) is to work with the leading islet isolation centers in the U.S. to distribute high quality human islets to the diabetes research community, in order to advance scientific discoveries and…

Action to Control Cardiovascular Disease Risk in Diabetes Follow-up Study
ACCORDION (sponsored by NHLBI) is a prospective, observational follow-up study of at least 8000 participants who were treated and followed in the Action to Control Cardiovascular Risk in Diabetes (ACCORD) Trial.  Treatment in ACCORD ended in 2009 and…
Action for Health in Diabetes
Look AHEAD is a 16-center, randomized clinical trial investigating the long-term health effects of an intensive lifestyle intervention designed to produce weight loss. Look AHEAD enrolled 5,145 overweight or obese participants with type 2 diabetes…
Diabetic Complications Consortium
The goal of the NIDDK-sponsored Diabetic Complications Consortium (DiaComp) is to foster communication and collaboration between investigator communities involved in complications research.  Toward this goal, DiaComp: (1) sponsors annual meetings in…

View Additional Research Resources


 NIDDK Active Trials in Diabetes

View related clinical trials from ClinicalTrials.gov.


 Related Study Sections

​Study sections conduct initial peer review of applications in a designated scientific area.View related study sections​ from the NIH's Center for Scientific Review.​