U.S. Department of Health and Human Services

Bioengineering, Biotechnology, and Imaging as applied to Diabetes, Metabolic, and Endocrine Diseases

The bioengineering, biotechnology, and imaging programs support research on the development and application of technologies for the diagnosis, monitoring, and treatment of diabetes and other endocrine and metabolic diseases. Studies within these programs are aimed at: analyzing and interpreting protein structures that are relevant to metabolic and endocrine diseases; studying networks of metabolites (metabolome), proteins (proteome), and neural systems (connectome) that are relevant to metabolic and endocrine diseases; developing tools to address the many roles of metabolites, proteins, and neural systems in the physiology and pathophysiology of metabolic and endocrine diseases; addressing the development and implementation of glucose sensors as well as their combination with insulin delivery systems to form a ‘closed-loop’ artificial pancreas; developing and applying in vivo molecular and functional imaging techniques to visualize and monitor physiological or metabolic processes and tissues (e.g., pancreatic beta cell mass, human brown adipose tissue, neural systems).

 

 

 NIDDK Staff

 
Guillermo A. Arreaza-Rubín, M.D.Diabetes and endocrine disease bioengineering and glucose sensingArthur L. Castle, Ph.D.Functional metabolomics and technology development to measure metabolic disease; fellowships and institutional training grantsMaren Laughlin, Ph.D.Integrative metabolism and physiology, and in vivo molecular and functional imaging, as relevant to energy balance in metabolic disease
Sheryl Sato, Ph.D.Basic mechanisms underlying the organogenesis and regeneration of pancreatic islets during health and diseaseSalvatore Sechi, Ph.D.Proteomics, Systems Biology, and Structural Biology as applied to diabetes, metabolic, and endocrine diseasesLuke E Stoeckel, Ph.D.Cognitive and clinical neuroscience of the non-homeostatic (i.e., extra-hypothalamic) contributions to obesity and diabetes and their complications

 

 Related Funding Opportunities

 
Posted DateTitleFull Announcement
11/25/2016Limited Competition: Research Resource for Human Organs and Tissues (U42) (Summary) RFA-OD-17-001
11/23/2016NIH Health Care Systems Research Collaboratory - Demonstration Projects for Pragmatic Clinical Trials (UG3/UH3) (Summary) RFA-RM-16-019
11/7/2016Coordinating Unit for the Mouse Metabolic Phenotyping Centers (U24) (Summary) RFA-DK-16-034
11/7/2016Coordinating Unit for Diabetic Complications Consortium (U24) (Summary) RFA-DK-16-036
10/27/2016NIDDK Exploratory Clinical Trials for Small Business (R44) (Summary) PAR-17-034
View More Funding Opportunities

The resources listed below include reagents, data, protocols, etc. If you would like to utilize any of these resources, contact the person associated with the resource.

 

 Research Resources

 
Resource NameDescription
Integrated Islet Distribution Program

The goal of the Integrated Islet Distribution Program (IIDP) is to work with the leading islet isolation centers in the U.S. to distribute high quality human islets to the diabetes research community, in order to advance scientific discoveries and…

Action to Control Cardiovascular Disease Risk in Diabetes Follow-up Study
ACCORDION (sponsored by NHLBI) is a prospective, observational follow-up study of at least 8000 participants who were treated and followed in the Action to Control Cardiovascular Risk in Diabetes (ACCORD) Trial.  Treatment in ACCORD ended in 2009 and…
Action for Health in Diabetes
Look AHEAD is a 16-center, randomized clinical trial investigating the long-term health effects of an intensive lifestyle intervention designed to produce weight loss. Look AHEAD enrolled 5,145 overweight or obese participants with type 2 diabetes…
Diabetic Complications Consortium
The goal of the NIDDK-sponsored Diabetic Complications Consortium (DiaComp) is to foster communication and collaboration between investigator communities involved in complications research.  Toward this goal, DiaComp: (1) sponsors annual meetings in…
Type 1 Diabetes-Rapid Access to Intervention Development
Type 1 Diabetes-Rapid Access to Intervention Development (T1D-RAID): T1D-RAID is not accepting new applications at this time, but currently supports ongoing projects. The goal of T1D-RAID is to facilitate translation from the lab to the clinic of…

View Additional Research Resources

 

 NIDDK Active Trials in Diabetes and Endocrine Disease

 
​View related clinical trials from ClinicalTrials.gov​.

 

 Related Study Sections

 
​Study sections conduct initial peer review of applications in a designated scientific area. View related study sections from the NIH's Center for Scientific Review.​

NIH Common Fund

Learn about current projects and view funding opportunities sponsored by the​ ​​NIH Common Fund.​