U.S. Department of Health and Human Services

Diabetes Genetics and Genomics

The Diabetes Genetics and Genomics program advances research to identify the genes and intergenic regions that predispose to or protect from developing type 1 or type 2 diabetes. In addition, research to define mechanisms underlying disease risk associated with genetic and genomic variation is also encouraged. By determining the genetic mechanisms underlying these diseases — and how genetic and epigenetic variation influence therapeutics — researchers should be able to develop better therapeutics and prevention strategies. Studies can involve the use of animal models to identify the genes responsible for development of or protection from the disease; research to develop genetic resources; creation of animal models for therapeutic trials; quantitative statistical and genetic methods to identify diabetes genes in human populations; investigation of the interactions of multiple genes and environmental factors; studies that determine genetic differences between populations that result in health disparities; and research to examine the genetics underlying variation in response to diabetes drugs.

 NIDDK Staff

Beena Akolkar, Ph.D.Clinical research in the prevention and immunopathogenesis of Type 1 Diabetes and the genetics and genomics of Type 1 and Type 2 Diabetes
Aaron Pawlyk, Ph.D.​Key regulators of intermediary metabolism; drug discovery; pharmacogenetics and precision medicine.


 Related Funding Opportunities

Posted DateTitleFull Announcement
10/7/2016BD2K Support for Meetings of Data Science Related Organizations (U13) (Summary) RFA-CA-16-020
8/24/2016Big Data to Knowledge (BD2K) Enhancing the Efficiency and Effectiveness of Digital Curation for Biomedical Big Data (U01) (Summary) RFA-LM-17-001
8/17/2016Identification of Mechanisms Mediating the Effects of Sleep on Diabetes-Related Metabolism in Humans (R01) (Summary) RFA-DK-16-005
8/16/2016Big Data to Knowledge (BD2K) Community-based Data and Metadata Standards Efforts (R24) (Summary) RFA-ES-16-010
8/10/2016BD2K Research Education Curriculum Development: Data Science Overview for Biomedical Scientists (R25) (Summary) RFA-ES-16-011
View More Funding Opportunities

The resources listed below include reagents, data, protocols, etc. If you would like to utilize any of these resources, contact the person associated with the resource.


 Research Resources

Resource NameDescription
Integrated Islet Distribution Program

The goal of the Integrated Islet Distribution Program (IIDP) is to work with the leading islet isolation centers in the U.S. to distribute high quality human islets to the diabetes research community, in order to advance scientific discoveries and…

Action to Control Cardiovascular Disease Risk in Diabetes Follow-up Study
ACCORDION (sponsored by NHLBI) is a prospective, observational follow-up study of at least 8000 participants who were treated and followed in the Action to Control Cardiovascular Risk in Diabetes (ACCORD) Trial.  Treatment in ACCORD ended in 2009 and…
Action for Health in Diabetes
Look AHEAD is a 16-center, randomized clinical trial investigating the long-term health effects of an intensive lifestyle intervention designed to produce weight loss. Look AHEAD enrolled 5,145 overweight or obese participants with type 2 diabetes…
Diabetic Complications Consortium
The goal of the NIDDK-sponsored Diabetic Complications Consortium (DiaComp) is to foster communication and collaboration between investigator communities involved in complications research.  Toward this goal, DiaComp: (1) sponsors annual meetings in…
Type 1 Diabetes-Rapid Access to Intervention Development
Type 1 Diabetes-Rapid Access to Intervention Development (T1D-RAID): T1D-RAID is not accepting new applications at this time, but currently supports ongoing projects. The goal of T1D-RAID is to facilitate translation from the lab to the clinic of…

View Additional Research Resources


 NIDDK Active Trials in Diabetes

View related clinical trials from ClinicalTrials.gov.​


 Related Study Sections

​Study sections conduct initial peer review of applications in a designated scientific area. View related study sections​ from the NIH's Center for Scientific Review.