U.S. Department of Health and Human Services

Motility and Functional Gastrointestinal Disorders

The Motility and Functional Gastrointestinal Disorders program supports basic, clinical, and translational research on aspects of gut physiology regulating motility, including research on the structure of gastrointestinal muscles and the biochemistry of contractile processes and mechano-chemical energy conversion relations between metabolism and contractility in smooth muscle; the basic biology of gut smooth muscle and the role of the nervous system in digestion and factors that affect gut motility; and the effect of gastrointestinal diseases and disorders on gastrointestinal motility.  The program also supports clinical trials to test new treatments for functional gastrointestinal disorders and epidemiology studies to address risk factors for disease occurrence, prognosis, or natural history.  Particular clinical areas of interest include irritable bowel syndrome, gastroparesis, functional dyspepsia, colonic diverticular disease, swallowing disorders, and gastroesophageal reflux.​​​​​​​​​​​​​​​​​​​​

 

 NIDDK Staff

 
Jill L. Carrington, Ph.D.Basic Neurogastroenterology; Gastrointestinal Development, Epithelial Biology, Stem Cell BiologyFrank Hamilton, M.D., M.P.H.Gastrointestinal and Nutrition AIDS; Gastrointestinal Endoscopy Research; Gastrointestinal Mucosa and Immunology; Gastrointestinal Motility
David Saslowsky, Ph.D.Career Development Programs (K awards)

 

 Related Funding Opportunities

 
Posted DateTitleFull Announcement
1/5/2017Research on the Health of Women of Underrepresented, Understudied and Underreported (U3) Populations An ORWH FY17 Administrative Supplement (Admin Supp) (Summary) PA-17-101
12/23/2016Administrative Supplements for Research on Sexual and Gender Minority (SGM) Populations (Admin Supp) (Summary) PA-17-098
12/12/2016Administrative Supplement for Research on Sex/Gender Influences (Admin Supp) (Summary) PA-17-078
12/1/2016Silvio O. Conte Digestive Diseases Research Core Centers (P30) (Summary) RFA-DK-17-001
11/25/2016Limited Competition: Research Resource for Human Organs and Tissues (U42) (Summary) RFA-OD-17-001
View More Funding Opportunities

The resources listed below include reagents, data, protocols, etc. If you would like to utilize any of these resources, contact the person associated with the resource.

 

 Research Resources

 
Resource NameDescription
Inflammatory Bowel Disease Genetic Consortium

The NIDDK Inflammatory Bowel Disease Genetics Consortium (IBDGC) consists of investigators from seven sites in the U.S. and Canada, who have recruited a large sample of inflammatory bowel disease patients, their relatives, and control subjects. All…

Diabetic Complications Consortium
The goal of the NIDDK-sponsored Diabetic Complications Consortium (DiaComp) is to foster communication and collaboration between investigator communities involved in complications research.  Toward this goal, DiaComp: (1) sponsors annual meetings in…
Predicting Response to Standardized Pediatric Colitis Therapy

The mission of the PROTECT Study is to provide a better understanding of how children newly diagnosed with ulcerative colitis (UC) respond to mesalamine and prednisone (corticosteroid), the standard initial therapies used to treat this disorder…

Intestinal Stem Cell Consortium

The mission of the ISCC is to advance the understanding of intestinal epithelial stem cell biology during development, homeostasis, regeneration and disease. The immediate goals of the ISCC are to isolate, characterize, culture and validate…

Hyperglycemia and Pregnancy Outcomes Follow-Up Study Consortium

The goal of this follow-up study of mothers who participated in the Hyperglycemia and Adverse Pregnancy Outcomes (HAPO) study, is to determine the levels of blood sugar during pregnancy that are linked to increased body fat in the child, and to a…

View Additional Research Resources

 

 NIDDK Active Trials in Gastrointestinal Disease

 
View related clinical trials from ClinicalTrials.gov.

 

 Related Study Sections

 
Study sections conduct initial peer review of applications in a designated scientific area. View related study sections from the NIH's Center for Scientific Review.