Doctors diagnose primary sclerosing cholangitis (PSC) based on your medical and family history, a physical exam, and the results of medical tests.
Your doctor will ask you about your symptoms. He or she may also ask whether
During a physical exam, your doctor may
Your doctor may also check for and ask about symptoms of a bile duct infection, which may include
Liver function tests can show abnormal liver enzyme levels in your blood. Abnormal levels of certain liver enzymes may be a sign of damage to your liver or bile ducts. Blood tests can also show higher-than-normal levels of certain antibodies in the blood, which may be a sign of PSC. Another blood test, called a white blood cell (WBC) count, measures the number of WBCs in your blood. A high WBC count may be a sign of a bile duct infection.
Your doctor may perform one or more of the following imaging tests of your liver and bile ducts:
In some cases, your doctor may perform a liver biopsy to
This content is provided as a service of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), part of the National Institutes of Health. The NIDDK translates and disseminates research findings to increase knowledge and understanding about health and disease among patients, health professionals, and the public. Content produced by the NIDDK is carefully reviewed by NIDDK scientists and other experts.
The NIDDK would like to thank:
Keith D. Lindor, M.D., Arizona State University