Doctors can’t cure primary sclerosing cholangitis (PSC) or keep the disease from getting worse. However, they can treat narrowed or blocked bile ducts and the symptoms and complications of PSC.
If your bile ducts are narrowed or blocked, your doctor may use medical procedures, such as endoscopic retrograde cholangiopancreatography (ERCP) and percutaneous transhepatic cholangiography, to open them and help keep them open.
Your doctor may recommend over-the-counter products and medicines or prescribe medicines to treat itchy skin. Over-the-counter products and medicines include
If you have low levels of fat-soluble vitamins in your body, your doctor may recommend dietary supplements of vitamins A, D, E, and K. Follow your doctor’s instructions on the type and amount of vitamins you should take.
Your doctor may prescribe an antibiotic to treat a bile duct infection.
If your PSC has caused cirrhosis, your doctor may treat the health problems related to cirrhosis with medicines, surgery, and other medical procedures. If cirrhosis leads to liver failure, you may need a liver transplant.
Your doctor may consider a liver transplant if your PSC has caused liver failure. Doctors consider liver transplants only after all other treatment options have failed.
To help prevent further liver damage, you can do the following:
This content is provided as a service of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), part of the National Institutes of Health. The NIDDK translates and disseminates research findings to increase knowledge and understanding about health and disease among patients, health professionals, and the public. Content produced by the NIDDK is carefully reviewed by NIDDK scientists and other experts.
The NIDDK would like to thank:
Keith D. Lindor, M.D., Arizona State University