Leslie J. Baier, Ph.D.

Section Chief: Diabetes Molecular Genetics Section, Phoenix Epidemiology & Clinical Research Branch

Scientific Focus Areas: Genetics and Genomics, Health Disparities, Stem Cell Biology, Molecular Biology and Biochemistry, Epidemiology

Publications

A selection of recent and significant publications can be viewed below.

Select Publications

Generation of Isogenic hiPSCs with Targeted Edits at Multiple Intronic SNPs to Study the Effects of the Type 2 Diabetes Associated KCNQ1 Locus in American Indians.: Nair AK, Traurig M, Sutherland JR, Muller YL, Grellinger ED, Saporito L, Nelson RG, Bogardus C, Baier LJ.; Cells (2022 Apr 25) 11. Abstract/Full Text
Characterization of Exome Variants and Their Metabolic Impact in 6,716 American Indians from the Southwest US.: Kim HI, Ye B, Gosalia N, Regeneron Genetics Center, Köroğlu Ç, Hanson RL, Hsueh WC, Knowler WC, Baier LJ, Bogardus C, Shuldiner AR, Van Hout CV.; Am J Hum Genet (2020 Aug 6) 107:251-264. Abstract/Full Text
Functional variants in cytochrome b5 type A (CYB5A) are enriched in Southwest American Indian individuals and associate with obesity.: Day SE, Traurig M, Kumar P, Piaggi P, Koroglu C, Kobes S, Hanson RL, Bogardus C, Baier LJ.; Obesity (Silver Spring) (2022 Feb) 30:546-552. Abstract/Full Text
ABCC8 R1420H Loss-of-Function Variant in a Southwest American Indian Community: Association With Increased Birth Weight and Doubled Risk of Type 2 Diabetes.: Baier LJ, Muller YL, Remedi MS, Traurig M, Piaggi P, Wiessner G, Huang K, Stacy A, Kobes S, Krakoff J, Bennett PH, Nelson RG, Knowler WC, Hanson RL, Nichols CG, Bogardus C.; Diabetes (2015 Dec) 64:4322-32. Abstract/Full Text
Exome Sequencing of 21 Bardet-Biedl Syndrome (BBS) Genes to Identify Obesity Variants in 6,851 American Indians.: Day SE, Muller YL, Koroglu C, Kobes S, Wiedrich K, Mahkee D, Kim HI, Van Hout C, Gosalia N, Ye B, Regeneron Genetics Center, Shuldiner AR, Knowler WC, Hanson RL, Bogardus C, Baier LJ.; Obesity (Silver Spring) (2021 Apr) 29:748-754. Abstract/Full Text

Additional Publications

Analysis of type 2 diabetes and obesity genetic variants in Mexican Pima Indians: Marked allelic differentiation among Amerindians at HLA.: Hsueh WC, Bennett PH, Esparza-Romero J, Urquidez-Romero R, Valencia ME, Ravussin E, Williams RC, Knowler WC, Baier LJ, Schulz LO, Hanson RL.; Ann Hum Genet (2018 Sep) 82:287-299. Abstract/Full Text
Identification and functional analysis of a novel G310D variant in the insulin-like growth factor 1 receptor (IGF1R) gene associated with type 2 diabetes in American Indians.: Muller YL, Skelton G, Piaggi P, Chen P, Nair A, Kobes S, Hsueh WC, Knowler WC, Hanson RL, Baier LJ, Bogardus C.; Diabetes Metab Res Rev (2018 May) 34:e2994. Abstract/Full Text
HLA-B*07, HLA-DRB1*07, HLA-DRB1*12, and HLA-C*03:02 Strongly Associate With BMI: Data From 1.3 Million Healthy Chinese Adults.: Shen J, Guo T, Wang T, Zhen Y, Ma X, Wang Y, Zhang ZX, Cai JP, Mao W, Zhu FM, Li JP, Wang ZL, Zhang DM, Liu ML, Shan XY, Zhang BW, Zhu CF, Deng ZH, Yu WJ, Chen Q, Li GL, Yang T, Lu S, Pan QQ, Fan S, Wang XY, Zhao X, Bi XY, Qiao YH, Su PC, Lv R, Li GY, Li HC, Pei B, Jiao LX, Shen G, Liu J, Feng ZH, Su YP, Xie YB, Di WY, Wang XY, Liu X, Zhang XP, Du D, Liu Q, Han Y, Chen JW, Gu M, Baier LJ, China Marrow Donor Program.; Diabetes (2018 May) 67:861-871. Abstract/Full Text
Using Luciferase Reporter Assays to Identify Functional Variants at Disease-Associated Loci.: Nair AK, Baier LJ.; Methods Mol Biol (2018) 1706:303-319. Abstract/Full Text
Admixture mapping in the Hispanic Community Health Study/Study of Latinos reveals regions of genetic associations with blood pressure traits.: Sofer T, Baier LJ, Browning SR, Thornton TA, Talavera GA, Wassertheil-Smoller S, Daviglus ML, Hanson R, Kobes S, Cooper RS, Cai J, Levy D, Reiner AP, Franceschini N.; PLoS One (2017) 12:e0188400. Abstract/Full Text
Erratum: Large meta-analysis of genome-wide association studies identifies five loci for lean body mass.: Zillikens MC, Demissie S, Hsu YH, Yerges-Armstrong LM, Chou WC, Stolk L, Livshits G, Broer L, Johnson T, Koller DL, Kutalik Z, Luan J, Malkin I, Ried JS, Smith AV, Thorleifsson G, Vandenput L, Hua Zhao J, Zhang W, Aghdassi A, Åkesson K, Amin N, Baier LJ, Barroso I, Bennett DA, Bertram L, Biffar R, Bochud M, Boehnke M, Borecki IB, Buchman AS, Byberg L, Campbell H, Campos Obanda N, Cauley JA, Cawthon PM, Cederberg H, Chen Z, Cho NH, Jin Choi H, Claussnitzer M, Collins F, Cummings SR, De Jager PL, Demuth I, Dhonukshe-Rutten RAM, Diatchenko L, Eiriksdottir G, Enneman AW, Erdos M, Eriksson JG, Eriksson J, Estrada K, Evans DS, Feitosa MF, Fu M, Garcia M, Gieger C, Girke T, Glazer NL, Grallert H, Grewal J, Han BG, Hanson RL, Hayward C, Hofman A, Hoffman EP, Homuth G, Hsueh WC, Hubal MJ, Hubbard A, Huffman KM, Husted LB, Illig T, Ingelsson E, Ittermann T, Jansson JO, Jordan JM, Jula A, Karlsson M, Khaw KT, Kilpeläinen TO, Klopp N, Kloth JSL, Koistinen HA, Kraus WE, Kritchevsky S, Kuulasmaa T, Kuusisto J, Laakso M, Lahti J, Lang T, Langdahl BL, Launer LJ, Lee JY, Lerch MM, Lewis JR, Lind L, Lindgren C, Liu Y, Liu T, Liu Y, Ljunggren Ö, Lorentzon M, Luben RN, Maixner W, McGuigan FE, Medina-Gomez C, Meitinger T, Melhus H, Mellström D, Melov S, Michaëlsson K, Mitchell BD, Morris AP, Mosekilde L, Newman A, Nielson CM, O'Connell JR, Oostra BA, Orwoll ES, Palotie A, Parker SCJ, Peacock M, Perola M, Peters A, Polasek O, Prince RL, Räikkönen K, Ralston SH, Ripatti S, Robbins JA, Rotter JI, Rudan I, Salomaa V, Satterfield S, Schadt EE, Schipf S, Scott L, Sehmi J, Shen J, Soo Shin C, Sigurdsson G, Smith S, Soranzo N, Stančáková A, Steinhagen-Thiessen E, Streeten EA, Styrkarsdottir U, Swart KMA, Tan ST, Tarnopolsky MA, Thompson P, Thomson CA, Thorsteinsdottir U, Tikkanen E, Tranah GJ, Tuomilehto J, van Schoor NM, Verma A, Vollenweider P, Völzke H, Wactawski-Wende J, Walker M, Weedon MN, Welch R, Wichmann HE, Widen E, Williams FMK, Wilson JF, Wright NC, Xie W, Yu L, Zhou Y, Chambers JC, Döring A, van Duijn CM, Econs MJ, Gudnason V, Kooner JS, Psaty BM, Spector TD, Stefansson K, Rivadeneira F, Uitterlinden AG, Wareham NJ, Ossowski V, Waterworth D, Loos RJF, Karasik D, Harris TB, Ohlsson C, Kiel DP.; Nat Commun (2017 Nov 7) 8:1414. Abstract/Full Text
A Loss-of-Function Splice Acceptor Variant in IGF2 Is Protective for Type 2 Diabetes.: Mercader JM, Liao RG, Bell AD, Dymek Z, Estrada K, Tukiainen T, Huerta-Chagoya A, Moreno-Macías H, Jablonski KA, Hanson RL, Walford GA, Moran I, Chen L, Agarwala V, Ordoñez-Sánchez ML, Rodríguez-Guillen R, Rodríguez-Torres M, Segura-Kato Y, García-Ortiz H, Centeno-Cruz F, Barajas-Olmos F, Caulkins L, Puppala S, Fontanillas P, Williams AL, Bonàs-Guarch S, Hartl C, Ripke S, Diabetes Prevention Program Research Group, Tooley K, Lane J, Zerrweck C, Martínez-Hernández A, Córdova EJ, Mendoza-Caamal E, Contreras-Cubas C, González-Villalpando ME, Cruz-Bautista I, Muñoz-Hernández L, Gómez-Velasco D, Alvirde U, Henderson BE, Wilkens LR, Le Marchand L, Arellano-Campos O, Riba L, Harden M, Broad Genomics Platform, Gabriel S, T2D-GENES Consortium, Abboud HE, Cortes ML, Revilla-Monsalve C, Islas-Andrade S, Soberon X, Curran JE, Jenkinson CP, DeFronzo RA, Lehman DM, Hanis CL, Bell GI, Boehnke M, Blangero J, Duggirala R, Saxena R, MacArthur D, Ferrer J, McCarroll SA, Torrents D, Knowler WC, Baier LJ, Burtt N, González-Villalpando C, Haiman CA, Aguilar-Salinas CA, Tusié-Luna T, Flannick J, Jacobs SBR, Orozco L, Altshuler D, Florez JC, SIGMA T2D Genetics Consortium.; Diabetes (2017 Nov) 66:2903-2914. Abstract/Full Text
Large meta-analysis of genome-wide association studies identifies five loci for lean body mass.: Zillikens MC, Demissie S, Hsu YH, Yerges-Armstrong LM, Chou WC, Stolk L, Livshits G, Broer L, Johnson T, Koller DL, Kutalik Z, Luan J, Malkin I, Ried JS, Smith AV, Thorleifsson G, Vandenput L, Hua Zhao J, Zhang W, Aghdassi A, Åkesson K, Amin N, Baier LJ, Barroso I, Bennett DA, Bertram L, Biffar R, Bochud M, Boehnke M, Borecki IB, Buchman AS, Byberg L, Campbell H, Campos Obanda N, Cauley JA, Cawthon PM, Cederberg H, Chen Z, Cho NH, Jin Choi H, Claussnitzer M, Collins F, Cummings SR, De Jager PL, Demuth I, Dhonukshe-Rutten RAM, Diatchenko L, Eiriksdottir G, Enneman AW, Erdos M, Eriksson JG, Eriksson J, Estrada K, Evans DS, Feitosa MF, Fu M, Garcia M, Gieger C, Girke T, Glazer NL, Grallert H, Grewal J, Han BG, Hanson RL, Hayward C, Hofman A, Hoffman EP, Homuth G, Hsueh WC, Hubal MJ, Hubbard A, Huffman KM, Husted LB, Illig T, Ingelsson E, Ittermann T, Jansson JO, Jordan JM, Jula A, Karlsson M, Khaw KT, Kilpeläinen TO, Klopp N, Kloth JSL, Koistinen HA, Kraus WE, Kritchevsky S, Kuulasmaa T, Kuusisto J, Laakso M, Lahti J, Lang T, Langdahl BL, Launer LJ, Lee JY, Lerch MM, Lewis JR, Lind L, Lindgren C, Liu Y, Liu T, Liu Y, Ljunggren Ö, Lorentzon M, Luben RN, Maixner W, McGuigan FE, Medina-Gomez C, Meitinger T, Melhus H, Mellström D, Melov S, Michaëlsson K, Mitchell BD, Morris AP, Mosekilde L, Newman A, Nielson CM, O'Connell JR, Oostra BA, Orwoll ES, Palotie A, Parker SCJ, Peacock M, Perola M, Peters A, Polasek O, Prince RL, Räikkönen K, Ralston SH, Ripatti S, Robbins JA, Rotter JI, Rudan I, Salomaa V, Satterfield S, Schadt EE, Schipf S, Scott L, Sehmi J, Shen J, Soo Shin C, Sigurdsson G, Smith S, Soranzo N, Stančáková A, Steinhagen-Thiessen E, Streeten EA, Styrkarsdottir U, Swart KMA, Tan ST, Tarnopolsky MA, Thompson P, Thomson CA, Thorsteinsdottir U, Tikkanen E, Tranah GJ, Tuomilehto J, van Schoor NM, Verma A, Vollenweider P, Völzke H, Wactawski-Wende J, Walker M, Weedon MN, Welch R, Wichmann HE, Widen E, Williams FMK, Wilson JF, Wright NC, Xie W, Yu L, Zhou Y, Chambers JC, Döring A, van Duijn CM, Econs MJ, Gudnason V, Kooner JS, Psaty BM, Spector TD, Stefansson K, Rivadeneira F, Uitterlinden AG, Wareham NJ, Ossowski V, Waterworth D, Loos RJF, Karasik D, Harris TB, Ohlsson C, Kiel DP.; Nat Commun (2017 Jul 19) 8:80. Abstract/Full Text
Admixture Mapping Identifies an Amerindian Ancestry Locus Associated with Albuminuria in Hispanics in the United States.: Brown LA, Sofer T, Stilp AM, Baier LJ, Kramer HJ, Masindova I, Levy D, Hanson RL, Moncrieft AE, Redline S, Rosas SE, Lash JP, Cai J, Laurie CC, Browning S, Thornton T, Franceschini N.; J Am Soc Nephrol (2017 Jul) 28:2211-2220. Abstract/Full Text
Assessing variation across 8 established East Asian loci for type 2 diabetes mellitus in American Indians: Suggestive evidence for new sex-specific diabetes signals in GLIS3 and ZFAND3.: Muller YL, Piaggi P, Chen P, Wiessner G, Okani C, Kobes S, Knowler WC, Bogardus C, Hanson RL, Baier LJ.; Diabetes Metab Res Rev (2017 May) 33. Abstract/Full Text
The impact of genetic variants on BMI increase during childhood versus adulthood.: Hohenadel MG, Baier LJ, Piaggi P, Muller YL, Hanson RL, Krakoff J, Thearle MS.; Int J Obes (Lond) (2016 Aug) 40:1301-9. Abstract/Full Text
Assessment of established HDL-C loci for association with HDL-C levels and type 2 diabetes in Pima Indians.: Nair AK, Piaggi P, McLean NA, Kaur M, Kobes S, Knowler WC, Bogardus C, Hanson RL, Baier LJ.; Diabetologia (2016 Mar) 59:481-91. Abstract/Full Text
Genome-wide Association Study of Platelet Count Identifies Ancestry-Specific Loci in Hispanic/Latino Americans.: Schick UM, Jain D, Hodonsky CJ, Morrison JV, Davis JP, Brown L, Sofer T, Conomos MP, Schurmann C, McHugh CP, Nelson SC, Vadlamudi S, Stilp A, Plantinga A, Baier L, Bien SA, Gogarten SM, Laurie CA, Taylor KD, Liu Y, Auer PL, Franceschini N, Szpiro A, Rice K, Kerr KF, Rotter JI, Hanson RL, Papanicolaou G, Rich SS, Loos RJ, Browning BL, Browning SR, Weir BS, Laurie CC, Mohlke KL, North KE, Thornton TA, Reiner AP.; Am J Hum Genet (2016 Feb 4) 98:229-42. Abstract/Full Text
Analysis of SLC16A11 Variants in 12,811 American Indians: Genotype-Obesity Interaction for Type 2 Diabetes and an Association With RNASEK Expression.: Traurig M, Hanson RL, Marinelarena A, Kobes S, Piaggi P, Cole S, Curran JE, Blangero J, Göring H, Kumar S, Nelson RG, Howard BV, Knowler WC, Baier LJ, Bogardus C.; Diabetes (2016 Feb) 65:510-9. Abstract/Full Text
Assessing FOXO1A as a potential susceptibility locus for type 2 diabetes and obesity in American Indians.: Muller YL, Hanson RL, Wiessner G, Nieboer L, Kobes S, Piaggi P, Abdussamad M, Okani C, Knowler WC, Bogardus C, Baier LJ.; Obesity (Silver Spring) (2015 Oct) 23:1960-5. Abstract/Full Text
Complex Genetics of Type 2 Diabetes and Effect Size: What have We Learned from Isolated Populations?: Nair AK, Baier LJ.; Rev Diabet Stud (2015 Fall-Winter) 12:299-319. Abstract/Full Text
The effect of differing patterns of childhood body mass index gain on adult physiology in American Indians.: Thearle MS, Votruba SB, Piaggi P, Muller YL, Hanson RL, Baier LJ, Knowler W, Krakoff J.; Obesity (Silver Spring) (2015 Sep) 23:1872-80. Abstract/Full Text
Role of Established Type 2 Diabetes-Susceptibility Genetic Variants in a High Prevalence American Indian Population.: Hanson RL, Rong R, Kobes S, Muller YL, Weil EJ, Curtis JM, Nelson RG, Baier LJ.; Diabetes (2015 Jul) 64:2646-57. Abstract/Full Text
Common genetic variation in and near the melanocortin 4 receptor gene (MC4R) is associated with body mass index in American Indian adults and children.: Muller YL, Thearle MS, Piaggi P, Hanson RL, Hoffman D, Gene B, Mahkee D, Huang K, Kobes S, Votruba S, Knowler WC, Bogardus C, Baier LJ.; Hum Genet (2014 Nov) 133:1431-41. Abstract/Full Text
Variants associated with type 2 diabetes identified by the transethnic meta-analysis study: assessment in American Indians and evidence for a new signal in LPP.: Nair AK, Muller YL, McLean NA, Abdussamad M, Piaggi P, Kobes S, Weil EJ, Curtis JM, Nelson RG, Knowler WC, Hanson RL, Baier LJ.; Diabetologia (2014 Nov) 57:2334-8. Abstract/Full Text
Brain-derived neurotrophic factor in human subjects with function-altering melanocortin-4 receptor variants.: Hohenadel MG, Thearle MS, Grice BA, Huang H, Dai MH, Tao YX, Hunter LA, Palaguachi GI, Mou Z, Kim RC, Tsang MM, Haack K, Voruganti VS, Cole SA, Butte NF, Comuzzie AG, Muller YL, Baier LJ, Krakoff J, Knowler WC, Yanovski JA, Han JC.; Int J Obes (Lond) (2014 Aug) 38:1068-74. Abstract/Full Text
Assessing accuracy of genotype imputation in American Indians.: Malhotra A, Kobes S, Bogardus C, Knowler WC, Baier LJ, Hanson RL.; PLoS One (2014) 9:e102544. Abstract/Full Text
Common genetic variation in the glucokinase gene (GCK) is associated with type 2 diabetes and rates of carbohydrate oxidation and energy expenditure.: Muller YL, Piaggi P, Hoffman D, Huang K, Gene B, Kobes S, Thearle MS, Knowler WC, Hanson RL, Baier LJ, Bogardus C.; Diabetologia (2014 Jul) 57:1382-90. Abstract/Full Text
Potential epigenetic dysregulation of genes associated with MODY and type 2 diabetes in humans exposed to a diabetic intrauterine environment: an analysis of genome-wide DNA methylation.: del Rosario MC, Ossowski V, Knowler WC, Bogardus C, Baier LJ, Hanson RL.; Metabolism (2014 May) 63:654-60. Abstract/Full Text
Whole exome sequencing identifies variation in CYB5A and RNF10 associated with adiposity and type 2 diabetes.: Huang K, Nair AK, Muller YL, Piaggi P, Bian L, Del Rosario M, Knowler WC, Kobes S, Hanson RL, Bogardus C, Baier LJ.; Obesity (Silver Spring) (2014 Apr) 22:984-8. Abstract/Full Text
Hyperphagia: current concepts and future directions proceedings of the 2nd international conference on hyperphagia.: Heymsfield SB, Avena NM, Baier L, Brantley P, Bray GA, Burnett LC, Butler MG, Driscoll DJ, Egli D, Elmquist J, Forster JL, Goldstone AP, Gourash LM, Greenway FL, Han JC, Kane JG, Leibel RL, Loos RJ, Scheimann AO, Roth CL, Seeley RJ, Sheffield V, Tauber M, Vaisse C, Wang L, Waterland RA, Wevrick R, Yanovski JA, Zinn AR.; Obesity (Silver Spring) (2014 Feb) 22 Suppl 1:S1-S17. Abstract/Full Text
A genome-wide association study in American Indians implicates DNER as a susceptibility locus for type 2 diabetes.: Hanson RL, Muller YL, Kobes S, Guo T, Bian L, Ossowski V, Wiedrich K, Sutherland J, Wiedrich C, Mahkee D, Huang K, Abdussamad M, Traurig M, Weil EJ, Nelson RG, Bennett PH, Knowler WC, Bogardus C, Baier LJ.; Diabetes (2014 Jan) 63:369-76. Abstract/Full Text
MAP2K3 is associated with body mass index in American Indians and Caucasians and may mediate hypothalamic inflammation.: Bian L, Traurig M, Hanson RL, Marinelarena A, Kobes S, Muller YL, Malhotra A, Huang K, Perez J, Gale A, Knowler WC, Bogardus C, Baier LJ.; Hum Mol Genet (2013 Nov 1) 22:4438-49. Abstract/Full Text
Human adipose microRNA-221 is upregulated in obesity and affects fat metabolism downstream of leptin and TNF-α.: Meerson A, Traurig M, Ossowski V, Fleming JM, Mullins M, Baier LJ.; Diabetologia (2013 Sep) 56:1971-9. Abstract/Full Text
NGSPE: A pipeline for end-to-end analysis of DNA sequencing data and comparison between different platforms.: Huang K, Yellapantula V, Baier L, Dinu V.; Comput Biol Med (2013 Sep) 43:1171-6. Abstract/Full Text
Strong parent-of-origin effects in the association of KCNQ1 variants with type 2 diabetes in American Indians.: Hanson RL, Guo T, Muller YL, Fleming J, Knowler WC, Kobes S, Bogardus C, Baier LJ.; Diabetes (2013 Aug) 62:2984-91. Abstract/Full Text
Identification of genetic variation that determines human trehalase activity and its association with type 2 diabetes.: Muller YL, Hanson RL, Knowler WC, Fleming J, Goswami J, Huang K, Traurig M, Sutherland J, Wiedrich C, Wiedrich K, Mahkee D, Ossowski V, Kobes S, Bogardus C, Baier LJ.; Hum Genet (2013 Jun) 132:697-707. Abstract/Full Text
Evidence for a role of LPGAT1 in influencing BMI and percent body fat in Native Americans.: Traurig MT, Orczewska JI, Ortiz DJ, Bian L, Marinelarena AM, Kobes S, Malhotra A, Hanson RL, Mason CC, Knowler WC, Bogardus C, Baier LJ.; Obesity (Silver Spring) (2013 Jan) 21:193-202. Abstract/Full Text
Variants in the LEPR gene are nominally associated with higher BMI and lower 24-h energy expenditure in Pima Indians.: Traurig MT, Perez JM, Ma L, Bian L, Kobes S, Hanson RL, Knowler WC, Krakoff JA, Bogardus C, Baier LJ.; Obesity (Silver Spring) (2012 Dec) 20:2426-30. Abstract/Full Text
Greater impact of melanocortin-4 receptor deficiency on rates of growth and risk of type 2 diabetes during childhood compared with adulthood in Pima Indians.: Thearle MS, Muller YL, Hanson RL, Mullins M, Abdussamad M, Tran J, Knowler WC, Bogardus C, Krakoff J, Baier LJ.; Diabetes (2012 Jan) 61:250-7. Abstract/Full Text
Association analyses of variants in the DIO2 gene with early-onset type 2 diabetes mellitus in Pima Indians.: Nair S, Muller YL, Ortega E, Kobes S, Bogardus C, Baier LJ.; Thyroid (2012 Jan) 22:80-7. Abstract/Full Text
SIRT1 is associated with a decrease in acute insulin secretion and a sex specific increase in risk for type 2 diabetes in Pima Indians.: Dong Y, Guo T, Traurig M, Mason CC, Kobes S, Perez J, Knowler WC, Bogardus C, Hanson RL, Baier LJ.; Mol Genet Metab (2011 Dec) 104:661-5. Abstract/Full Text
A genome-wide association study of BMI in American Indians.: Malhotra A, Kobes S, Knowler WC, Baier LJ, Bogardus C, Hanson RL.; Obesity (Silver Spring) (2011 Oct) 19:2102-6. Abstract/Full Text
HLA-DRB1 reduces the risk of type 2 diabetes mellitus by increased insulin secretion.: Williams RC, Muller YL, Hanson RL, Knowler WC, Mason CC, Bian L, Ossowski V, Wiedrich K, Chen YF, Marcovina S, Hahnke J, Nelson RG, Baier LJ, Bogardus C.; Diabetologia (2011 Jul) 54:1684-92. Abstract/Full Text
Bimodal distribution of RNA expression levels in human skeletal muscle tissue.: Mason CC, Hanson RL, Ossowski V, Bian L, Baier LJ, Krakoff J, Bogardus C.; BMC Genomics (2011 Feb 7) 12:98. Abstract/Full Text
Evaluation of A2BP1 as an obesity gene.: Ma L, Hanson RL, Traurig MT, Muller YL, Kaur BP, Perez JM, Meyre D, Fu M, Körner A, Franks PW, Kiess W, Kobes S, Knowler WC, Kovacs P, Froguel P, Shuldiner AR, Bogardus C, Baier LJ.; Diabetes (2010 Nov) 59:2837-45. Abstract/Full Text
Functional variants in MBL2 are associated with type 2 diabetes and pre-diabetes traits in Pima Indians and the old order Amish.: Muller YL, Hanson RL, Bian L, Mack J, Shi X, Pakyz R, Shuldiner AR, Knowler WC, Bogardus C, Baier LJ.; Diabetes (2010 Aug) 59:2080-5. Abstract/Full Text
Variants in ACAD10 are associated with type 2 diabetes, insulin resistance and lipid oxidation in Pima Indians.: Bian L, Hanson RL, Muller YL, Ma L, MAGIC Investigators, Kobes S, Knowler WC, Bogardus C, Baier LJ.; Diabetologia (2010 Jul) 53:1349-53. Abstract/Full Text
Involvement of the chemokine-like receptor GPR33 in innate immunity.: Bohnekamp J, Böselt I, Saalbach A, Tönjes A, Kovacs P, Biebermann H, Manvelyan HM, Polte T, Gasperikova D, Lkhagvasuren S, Baier L, Stumvoll M, Römpler H, Schöneberg T.; Biochem Biophys Res Commun (2010 May 28) 396:272-7. Abstract/Full Text
Variants in ASK1 are associated with skeletal muscle ASK1 expression, in vivo insulin resistance, and type 2 diabetes in Pima Indians.: Bian L, Hanson RL, Ossowski V, Wiedrich K, Mason CC, Traurig M, Muller YL, Kobes S, Knowler WC, Baier LJ, Bogardus C.; Diabetes (2010 May) 59:1276-82. Abstract/Full Text

Last Reviewed November 2023