Event Details
Agenda
Event Details
Meeting Objectives
The International Conference on Diabetes and Depression is a multidisciplinary meeting focused on the co-morbidity of these two significant, chronic conditions. The primary goals of the Conference are to (1) present current research related to the pathogenesis, prevention, and treatment of co-morbid diabetes and depression; and (2) identify important research gaps and opportunities that are likely to lead to improved care and outcomes for co-morbid diabetes and depression. The meeting will include expert speakers, discussants, and panelists who can address these issues from the United States' and global perspectives.
Agenda
October 9, 2012
Introduction and Background
- 8:30 a.m.
- Introduction-Opening Remarks
Christine Hunter, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
- Remarks from National Institute of Mental Health (NIMH): Setting the Stage
Tom Insel, Director, NIMH
- 8:45 a.m.
- Broad Overview of the Meeting and the State-of-the-Science:
- Incidence, Prevalence, and Bi-directionality of the Diabetes and Depression Association
Sherita Golden
- Public Health Impact of Co-morbid Diabetes and Depression
Norman Sartorius
Session 1: Mechanisms Linking Diabetes and Depression
Session Chairs: Irwin Lucki, Ph.D., and Sherita Golden, M.D., M.H.S
- 9:15 a.m.
- Mechanisms Linking Diabetes and Depression: Session Introduction
Irwin Lucki
- 9:20 a.m.
- Overview of Potential Mechanisms for the Link Between Diabetes and Depression
Khalida Ismail
NEUROENDOCRINE FACTORS
Hypothalamic-Pituitary-Adrenal (HPA) Axis
- 9:40 a.m.
- The Role of the HPA Axis in Neuroplasticity as a Link to Depression and Cognitive Co-morbidities in Animal Models of Diabetes
Alexis Stranahan
- 10:00 a.m.
- Evidence of HPA Axis Dysfunction in Depression and Diabetes in Clinical and Population-based Studies
Sherita Golden
- 10:15 a.m.
- Depression and Risk of Cognitive Decline in Diabetes-Evidence From Human Studies
Rachel Whitmer
- 10:30 a.m.
- Question-and-Answer Session
Moderator: Irwin Lucki
- 10:50 a.m.
- Remarks from NIDDK: Setting the Stage
Griffin Rodgers, Director, NIDDK
- 11:00 a.m.
- Break
Circadian Rhythms and Sleep Disturbance
- 11:20 a.m.
- The Role of Circadian Rhythms in Regulating Metabolism-Basic Science Mechanisms
Orefeu Buxton
- 11:35 a.m.
- Effects of Sleep Disturbances on Metabolic Function, Diabetes Risk, and Depression
David Ehrmann
- 11:50 a.m.
- Question-and-Answer Session
Moderator: Irwin Lucki
- 12:10 p.m.
- Lunch: Boxed Lunch With Advance Purchase
Inflammation
- 1:10 p.m.
- The Role of Inflammation and Immunological Challenge as a Bridge Between Depression and Diabetes-Lessons From Animal Models
Robert Dantzer
- 1:25 p.m.
- Evidence of Inflammation in the Pathophysiology of Depression and Diabetes in Human Studies
Charles Raison
- 1:40 p.m.
- Question-and-Answer Session
Moderator: Sherita Golden
BEHAVIORAL, PSYCHOSOCIAL, AND ENVIRONMENTAL FACTORS
- 1:55 p.m.
- Contextual Factors in Diabetes and Depression
Tiffany Webb-Gary
- 2:10 p.m.
- Diabetes Distress Versus Depression: Implications for Glycemic Control
Mary de Groot
- 2:25 p.m.
- Adherence to Diabetes Self-care Behaviors in Depression
Jeff Gonzalez
- 2:40 p.m.
- Depression in Children with Diabetes
Maria Kovacs
- 2:55 p.m.
- Question-and-Answer Session
Moderator: Peter Muehrer
- 3:15 p.m
- Break
TREATMENT FACTORS
- 3:35 p.m.
- Antidepressant Treatments in Animal Models of Diabetes
Irwin Lucki
- 3:50 p.m.
- Association of Antidepressant and Antipsychotic Treatments With Obesity and Incident Diabetes in Population-based Studies
Richard Holt
- 4:05 p.m.
- Question-and-Answer Session
Moderator: Sherita Golden
- 4:25 p.m.
- Panel Discussion: Implications for Clinical and Behavioral Research? What Are the Crucial Unanswered Research Questions?
Alan Jacobson and Robert Ratner
- Question-and-Answer Session
Moderator: Christine Hunter
- 5:05 p.m.
- Wrap-up and Logistics for Day 2
Christine Hunter
October 10, 2012
- 8:00 a.m.
- Welcome Back and Orientation to the Day's Schedule
Peter Muehrer
Session 2: Treatment
Session Chair: Wayne Katon, M.D., and Mary de Groot, Ph.D.
- 8:10 a.m.
- Session Introduction
Wayne Katon
- 8:25 a.m.
- Are Evidenced-based Depression Treatments Effective in Treating Co-morbid Depression in Patients With Diabetes, and Do These Treatments Improve Diabetes Disease Control?
Christina van der Feltz-Cornelis
- 8:45 a.m.
- Question-and-Answer Session
Moderator: Mary de Groot
- 9:00 a.m.
- Improving Depression Outcomes in Large Populations of Patients With Diabetes: Collaborative Depression Care
Paul Ciechanowski
- 9:20 a.m.
- Question-and-Answer Session
Moderator: Wayne Katon
- 9:35 a.m.
- Multi-condition Collaborative Care for Both Depression and Diabetes
Wayne Katon
- 9:55 a.m.
- Question-and-Answer Session
Moderator: Mary de Groot
- 10:10 a.m.
- Break
- 10:30 a.m.
- Effect of Improving Diabetes Disease Control in Large Populations of Patients With Diabetes on Psychological Distress and Well-being
Patrick O'Connor
- 10:50 a.m.
- Question-and-Answer Session
Moderator: Wayne Katon
- 11:05 a.m
- Improving Depressive Symptoms and HbA1C Outcomes in Patients With Type I Diabetes
Alan Jacobson
- 11:25 a.m.
- Question-and-Answer Session
Moderator: Mary de Groot
- 11:40 a.m
- Panel Discussion: What are the Crucial Unanswered Research Questions?
John Hayes and Arie Nouwen
- Question-and-Answer Session
Moderator: Peter Muehrer
- 12:15 p.m.
- Lunch: Boxed Lunch With Advance Purchase
Session 3: Prevention and Public Health
Session Chairs: Richard Holt, Ph.D., F.R.C.P., and Norman Sartorius, M.D., Ph.D.
- 1:15 p.m.
- Session Introduction
Richard Holt
- 1:30 p.m.
- Prevention of Diabetes in Those With Depression: Findings From the Major Diabetes Prevention Trials
David Marrero
- 1:50 p.m.
- Question-and-Answer Session
Moderator: Richard Holt
- 2:05 p.m.
- Prevention of Depression in Those With Diabetes
Edwin Fisher
- 2:25 p.m.
- Question-and-Answer Session
Moderator: Richard Holt
- 2:40 p.m.
- Break
- 3:00 p.m.
- Roundtable
Chair: Norman Sartorius
- Dissemination, Implementation, and Public Health Panel: The Evidence and Research Needs in Health Policy, Health Education, and Health Economics Related to the Prevention and Management of Co-morbid Diabetes and Depression
Panel: Santosh Chaturvedi, Leonard Egede, Edwin Fisher,Wayne Katon, David McDaid, Brian Oldenberg, François Pouwer, Robert Ratner, and Richard Robert
- 4:30 p.m.
- Concluding Remarks
Sherita Gordon and Norman Sartorius