2020 Mid-Atlantic Diabetes and Obesity Research Symposium

Event Details

Background

The 2020 Annual Mid-Atlantic Diabetes and Obesity Research Symposium by Zoom is co-sponsored by the Diabetes, Endocrinology, and Obesity Branch (DEOB) at the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), National Institutes of Health (NIH); and the Mid-Atlantic Nutrition Obesity Research Center (NORC) at the Department of Medicine, University of Maryland School of Medicine (UM-SOM).

Meeting Objectives

The purposes of this meeting are to encourage collaborations and enhance interactions at the regional level through the sharing of both reagents and expertise.

Organizing Committee

Sam Cushman, Carol Haft, Marc Reitman, Artie Sherman, Ranganath Muniyappa, Connie Noguchi, Sushil Rane, Michael Krashes, Oksana Gavrilova, Aaron Cypess, Barbara Linder, Will Wong (Johns Hopkins University School of Medicine), and Simeon Taylor (UM-SOM).

Honorary Chairs

Lester Salans, M.D., and Jesse Roth, M.D.

Registration Deadline

September 16, 2020

Agenda

September 25, 2020

Honorary Chairs: Lester Salans and Jesse Roth

Organizing Committee: Sam Cushman, Aaron Cypess, Oksana Gavrilova, Michael Krashes, Carol Haft, Barbara Linder, Ranganath Muniyappa, Connie Noguchi, Sushil Rane, Marc Reitman, Artie Sherman, Simeon Taylor (UM-SOM), and William Wong (Johns Hopkins University School of Medicine)

8:30 a.m.

Zoom Opens

8:50 a.m. – 9:00 a.m.

Welcome and Introduction
Sam Cushman, Ph.D., National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

SESSION 1

Scientific Moderator: Simeon Taylor, M.D., Ph.D., University of Maryland School of Medicine
Zoom Moderator: Burnel Wilkins, NIDDK Conference Support, NIH

9:00 a.m. – 9:30 a.m.

Recent Artificial Pancreas Advances: From Validated Hybrid Systems to Full Closed Loop and Glycemic Disturbances Anticipation
Marc Breton, Ph.D., Center for Diabetes Technology, University of Virginia

9:30 a.m. – 9:45 a.m.

Alpha-GSU-Cre as Incidental Driver of Pancreatic Islet Cell Glucokinase Expression Causing Hyperinsulinemia
Kevin Chen, University of Pennsylvania

9:45 a.m. – 10:00 a.m.

Novel Metabolic Role for Brain-derived Neurotrophic Factor in Pancreatic β-Cell Insulin Secretion
Zhenyi Hong, Ph.D., Mouse Cancer Genetics Program, Center for Cancer Research, National Cancer Institute (NCI)

10:00 a.m. – 10:30 a.m.

Monogenic? Atypical? The State of Precision Medicine in Diabetes Mellitus
Toni Pollin, Ph.D., University of Maryland School of Medicine

10:30 a.m. – 10:45 a.m.

Break

10:45 a.m. – 10:50 a.m.

Welcoming Remarks
Griffin P. Rodgers, M.D., NIDDK

BREAKOUT SESSIONS

Breakout Session A
Scientific Moderator: Aaron Cypess, M.D., Ph.D., NIDDK
Zoom Moderator: Carol Kong, M.S., NIDDK

10:50 a.m. – 11:05 a.m.

Racial Disparities among Participants in Clinical Trials for Inherited Forms of Lipodystrophy, a Rare Disorder, Based on Genomic Databases
Brent Abel, NIDDK

11:05 a.m. – 11:20 a.m.

Meal-related Changes in Apolipoprotein Particles after Treatment with an Antisense Oligonucleotide to Apolipoprotein CIII
Brianna Brite, NIDDK

11:20 a.m. – 11:35 a.m.

β3-Adrenergic Receptors Regulate Human Brown/Beige Adipocyte Lipolysis and Thermogenesis
Cheryl Cero, Ph.D., NIDDK

11:35 a.m. – 11:50 a.m.

Retrospective Data Analysis of the Common Genetic Component Contributing to Obesity and Asthma
Lama Elzohary, Ph.D., George Mason University

11:50 a.m. – 12:05 p.m.

Understanding Facilitators and Barriers to Dietary Management among Hispanic Men with Type 2 Diabetes: Perceptions of Health Professionals
Leah Galitzdorfer, M.S., Brooklyn College

12:05 p.m. – 12:20 p.m.

Stimulation of β3-Adrenergic Receptors Primes Human White and Brown Adipocytes for Increased Lipolysis and Thermogenesis
Hannah Lea, NIDDK

Breakout Session B

Scientific Moderator: Arthur Sherman, Ph.D., NIDDK
Zoom Moderator: Marc Reitman, Ph.D., M.D., NIDDK

10:50 a.m. – 11:05 a.m.

Model Disposition Index: Assessing Abnormal Glucose Tolerance
Joon Ha, Ph.D., NIDDK

11:05 a.m. – 11:20 a.m.

Afro-Caribbeans with Type 2 Diabetes Are Younger and Have Lower BMI Than African Americans: The New York City Health and Nutrition Examination Survey (NYC HANES) 2013–14
Margrethe F. Horlyck-Romanovsky, Ph.D., Brooklyn College

11:20 a.m. – 11:35 a.m.

Africans Who Arrive in the United States Less Than 20 Years of Age Maintain Cultural Identity and Cardiometabolic Health: Insight from the Africans in America Study
Thomas Hormenu, Ph.D., NIDDK

11:35 a.m. – 11:50 a.m.

HbA1c and the Risk of Misclassification of Prediabetes and Diabetes in Heterogeneous African Descent Populations in the United States: A Scoping Review
Lakshay Khosla, SUNY Downstate Health Sciences University

11:50 a.m. – 12:05 p.m.

Cryptochrome Activator KL001 Potentially Binds to GLUD1 Enzyme and Other Aging-related Protein Targets
Jimmy Ngo, M.S., George Mason University

Breakout Session C

Scientific Moderator: Ranganath Muniyappa, M.D., Ph.D., NIDDK
Zoom Moderator: Juan Quiel, Ph.D., NIDDK

10:50 a.m. – 11:05 a.m.

COVID-19 Patients: Rates of Smell and Taste Loss across Clinical Studies
Eunice Chen, Ph.D., Temple University

11:05 a.m. – 11:20 a.m.

Ranges of Blood Ketone Levels after 2 Weeks of Inpatient Ad libitum Low-carbohydrate Diet
Lauren Milley, NIDDK

11:20 a.m. – 11:35 a.m.

Effect of Long-term Metreleptin Treatment on Glycemic Control in Rabson-Mendenhall Syndrome
Marinna Okawa, NIDDK

11:35 a.m. – 11:50 a.m.

The Combination of Antioxidant and β3-AR Modulates Meta-inflammation and Restores Catecholamine Sensitivity in White Adipose Tissue
Annie Pierce, NIDDK

11:50 a.m. – 12:05 p.m.

Pathway Analysis of Epicardial Adipose Tissue and Myocardium in Differential Body Mass States
Kerianne Richards, M.S., George Mason University

12:20 p.m. – 1:15 p.m.

Lunch Break

SESSION 2

Scientific Moderator: Marc Reitman, M.D., Ph.D., NIDDK
Zoom Moderator: Burnel Wilkins, NIDDK Conference Support, NIH

1:15 p.m. – 1:45 p.m.

Gut-Brain Effects on Neural Activity
Amber Alhadeff, Ph.D., Monell Chemical Senses Center, University of Pennsylvania

1:45 p.m. – 2:00 p.m.

Interrogating the Role of AgRP Neurons in the Pathogenesis of Activity-based Anorexia
Amy K. Sutton, Ph.D., NIDDK

2:00 p.m. – 2:15 p.m.

Thermoregulation: Introducing the Concept of the Thermoneutral Point
Vojtěch Škop, Ph.D., NIDDK

2:15 p.m. – 2:30 p.m.

Break

SESSION 3

Scientific Moderator: William Wong, Ph.D., Johns Hopkins University School of Medicine
Zoom Moderator: Burnel Wilkins, NIDDK Conference Support, NIH

2:30 p.m. – 3:00 p.m.

Estrogen-related Receptor Signaling: Pathways Controlling Adaptive Responses in Adipose Tissue and Skeletal Muscle
Anastasia Kralli, Ph.D., Johns Hopkins University School of Medicine

3:00 p.m. – 3:15 p.m.

Selective Activation of α Cell Gq Signaling Improves Glucose Tolerance and Insulin Sensitivity in Mice
Liu Liu, Ph.D., NIDDK

3:15 p.m. – 3:30 p.m.

Defining the Influence of Type 2 Diabetes on the Growing Skeleton: Early Insights and Next Steps
Joseph M. Kindler, Ph.D., The University of Georgia

3:30 p.m. – 4:00 p.m.

Microbiota, Bile Acids, Intestinal Nuclear Receptor Signaling, and Metabolic Diseases
Frank Gonzalez, Ph.D., NCI

4:00 p.m.

Adjournment

Abstracts

Submission Deadline

August 31, 2020

Submitting Abstracts

Participants in the 2020 Mid-Atlantic Diabetes and Obesity Research Symposium by Zoom—cosponsored by the Diabetes, Endocrinology, and Obesity Branch at the NIDDK and the Mid-Atlantic Nutrition Obesity Research Center (NORC) at the Department of Medicine, University of Maryland School of Medicine—are encouraged to submit abstracts of their research activities. All conference attendees who submit abstracts will have an opportunity to orally present their research in a Zoom session. In addition, all abstracts will be electronically available to all participants, along with a roster of participants containing their contact information, which is intended to provide researchers with additional career development and networking opportunities.

Five abstracts will be chosen for a short “hot topic” (10-minute) oral presentation followed by a brief discussion. The remaining abstracts will be scheduled as one of five 5-minute oral presentations with brief discussion in as many 60-minute breakout sessions as necessary to accommodate all abstract submissions.

All abstracts must be submitted via email to Rachel Pisarski of The Scientific Consulting Group, Inc., with “Mid-Atlantic Abstract” in the subject line. Abstract submissions should be no longer than 250 words (not including name and affiliation). Please make sure to read the formatting requirements below very carefully. It is extremely important that you follow these specifications.

Formatting Requirements

1. The abstract should be an MS Word document, typed and single-spaced using Times New Roman font. Everything but the title should be in normal, 12-point font.
   1. The abstract’s title should be Bold, 16-Point, Title Case font and should clearly represent the nature of the investigation.
   2. On the first line after the title, list the authors’ first and last names, degree, affiliation, city, state, and country.
   3. Separate multiple authors with a semicolon and underline the primary author’s name (one primary author per abstract).
   4. Use one blank line between the title and the body of the abstract and between paragraphs.
   5. The abstract file name should follow this format: primary author’s LastName_FirstWordOfTitle (e.g., Zucker_Effects).
2. Please ensure that your abstract is the correct length (250 words or less) and use 1-inch margins.
3. The use of standard abbreviations is desirable (e.g., RBC), as well as standard symbols for units of measure (e.g., kg, g, mg, mL, L, and %). Place nonstandard or unusual abbreviations within parentheses after the full word the first time that it appears. Use numerals to indicate numbers, except to begin sentences. Do not use subtitles (e.g., Methods, Results).
4. Simple tables or graphs may be included; however, they must fit within the designated abstract space of one page.

Organize the body of the abstract as follows:

1. Statement of the purpose of the study/program/project
2. Statement of the methods used
3. Summary of the results presented in sufficient detail to support the conclusion
4. Statement of the conclusions reached