Lily Ng, Ph.D.

Scientific Focus Areas: Cell Biology, Developmental Biology, Molecular Biology and Biochemistry


A selection of recent and significant publications can be viewed below.

Effects of two different knee tape procedures on lower-limb kinematics and kinetics in recreational runners.
Howe A, Campbell A, Ng L, Hall T, Hopper D.
Scand J Med Sci Sports (2015 Aug) 25:517-24. Abstract/Full Text
A multigene assay identifying distinct prognostic subtypes of clear cell renal cell carcinoma with differential response to tyrosine kinase inhibition.
Choudhury Y, Wei X, Chu YH, Ng LG, Tan HS, Koh V, Thike AA, Poon E, Ng QS, Toh CK, Kanesvaran R, Tan PH, Tan MH.
Eur Urol (2015 Jan) 67:17-20. Abstract/Full Text
Primary paranode demyelination modulates slowly developing axonal depolarization in a model of axonal injury.
Volman V, Ng LJ.
J Comput Neurosci (2014 Dec) 37:439-57. Abstract/Full Text
Supplementation of standard pre-oxygenation with nasal prong oxygen or machine oxygen flush during a simulated leak scenario.
Russell T, Ng L, Nathan E, Debenham E.
Anaesthesia (2014 Oct) 69:1133-7. Abstract/Full Text
Benefits of high-dose N-acetylcysteine to exacerbation-prone patients with COPD.
Tse HN, Raiteri L, Wong KY, Ng LY, Yee KS, Tseng CZS.
Chest (2014 Sep) 146:611-623. Abstract/Full Text
Development and evaluation of baculovirus-expressed Chikungunya virus E1 envelope proteins for serodiagnosis of Chikungunya infection.
Kumar P, Pok KY, Tan LK, Angela C, Leo YS, Ng LC.
J Virol Methods (2014 Sep) 206:67-75. Abstract/Full Text
Low torque levels can initiate a removal of the passivation layer and cause fretting in modular hip stems.
Jauch SY, Coles LG, Ng LV, Miles AW, Gill HS.
Med Eng Phys (2014 Sep) 36:1140-6. Abstract/Full Text
Plasma Bmi1 mRNA as a potential prognostic biomarker for distant metastasis in colorectal cancer patients.
Pun JC, Chan JY, Chun BK, Ng KW, Tsui SY, Wan TM, Lo O, Poon JT, Ng L, Pang R.
Mol Clin Oncol (2014 Sep) 2:817-820. Abstract/Full Text
Mutual touch during mother-infant face-to-face still-face interactions: influences of interaction period and infant birth status.
Mantis I, Stack DM, Ng L, Serbin LA, Schwartzman AE.
Infant Behav Dev (2014 Aug) 37:258-67. Abstract/Full Text
Efficacy and safety of celgosivir in patients with dengue fever (CELADEN): a phase 1b, randomised, double-blind, placebo-controlled, proof-of-concept trial.
Low JG, Sung C, Wijaya L, Wei Y, Rathore APS, Watanabe S, Tan BH, Toh L, Chua LT, Hou Y, Chow A, Howe S, Chan WK, Tan KH, Chung JS, Cherng BP, Lye DC, Tambayah PA, Ng LC, Connolly J, Hibberd ML, Leo YS, Cheung YB, Ooi EE, Vasudevan SG.
Lancet Infect Dis (2014 Aug) 14:706-715. Abstract/Full Text
An integrated physiology model to study regional lung damage effects and the physiologic response.
Shelley DA, Sih BL, Ng LJ.
Theor Biol Med Model (2014 Jul 21) 11:32. Abstract/Full Text
A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Thompson CL, Ng L, Menon V, Martinez S, Lee CK, Glattfelder K, Sunkin SM, Henry A, Lau C, Dang C, Garcia-Lopez R, Martinez-Ferre A, Pombero A, Rubenstein JLR, Wakeman WB, Hohmann J, Dee N, Sodt AJ, Young R, Smith K, Nguyen TN, Kidney J, Kuan L, Jeromin A, Kaykas A, Miller J, Page D, Orta G, Bernard A, Riley Z, Smith S, Wohnoutka P, Hawrylycz MJ, Puelles L, Jones AR.
Neuron (2014 Jul 16) 83:309-323. Abstract/Full Text
A three-dimensionally engineered biomimetic cartilaginous tissue model for osteoarthritic drug evaluation.
Peck Y, Ng LY, Goh JY, Gao C, Wang DA.
Mol Pharm (2014 Jul 7) 11:1997-2008. Abstract/Full Text
Effects of lithium on age-related decline in mitochondrial turnover and function in Caenorhabditis elegans.
Tam ZY, Gruber J, Ng LF, Halliwell B, Gunawan R.
J Gerontol A Biol Sci Med Sci (2014 Jul) 69:810-20. Abstract/Full Text
Family-based prevention of mental health problems in children affected by HIV and AIDS: an open trial.
Betancourt TS, Ng LC, Kirk CM, Munyanah M, Mushashi C, Ingabire C, Teta S, Beardslee WR, Brennan RT, Zahn I, Stulac S, Cyamatare FR, Sezibera V.
AIDS (2014 Jul) 28 Suppl 3:S359-68. Abstract/Full Text
Neurologic aspects of cardiac emergencies.
Ng L, Wang J, Altaweel L, Athar MK.
Crit Care Clin (2014 Jul) 30:557-84. Abstract/Full Text
Mechanisms of pyrethroid resistance in the dengue mosquito vector, Aedes aegypti: target site insensitivity, penetration, and metabolism.
Kasai S, Komagata O, Itokawa K, Shono T, Ng LC, Kobayashi M, Tomita T.
PLoS Negl Trop Dis (2014 Jun) 8:e2948. Abstract/Full Text
Anti-melanogenic effects of δ-tocotrienol are associated with tyrosinase-related proteins and MAPK signaling pathway in B16 melanoma cells.
Ng LT, Lin LT, Chen CL, Chen HW, Wu SJ, Lin CC.
Phytomedicine (2014 Jun 15) 21:978-83. Abstract/Full Text
CD41 is a reliable identification and activation marker for murine basophils in the steady state and during helminth and malarial infections.
Bakocevic N, Claser C, Yoshikawa S, Jones LA, Chew S, Goh CC, Malleret B, Larbi A, Ginhoux F, de Lafaille MC, Karasuyama H, Renia L, Ng LG.
Eur J Immunol (2014 Jun) 44:1823-34. Abstract/Full Text
The mitochondria-targeted antioxidant MitoQ extends lifespan and improves healthspan of a transgenic Caenorhabditis elegans model of Alzheimer disease.
Ng LF, Gruber J, Cheah IK, Goo CK, Cheong WF, Shui G, Sit KP, Wenk MR, Halliwell B.
Free Radic Biol Med (2014 Jun) 71:390-401. Abstract/Full Text
Central stentoplasty: technique for unipedicular single midline vertebral body stent implantation.
Pua U, Quek LH, Ng LC.
Cardiovasc Intervent Radiol (2014 Jun) 37:810-4. Abstract/Full Text
Improved analysis of vitamin D metabolites in plasma using liquid chromatography tandem mass spectrometry, and its application to cardiovascular research.
Sandhu JK, Auluck J, Ng LL, Jones DJ.
Biomed Chromatogr (2014 Jun) 28:913-7. Abstract/Full Text
Chikungunya in Singapore--the battle continues.
Oon LL, Ng LC.
Ann Acad Med Singapore (2014 Jun) 43:325-7. Abstract/Full Text
Dysregulation of miR-31 and miR-375 expression is associated with clinical outcomes in oral carcinoma.
Siow MY, Ng LP, Vincent-Chong VK, Jamaludin M, Abraham MT, Abdul Rahman ZA, Kallarakkal TG, Yang YH, Cheong SC, Zain RB.
Oral Dis (2014 May) 20:345-51. Abstract/Full Text
Abscisic acid perception and signaling: structural mechanisms and applications.
Ng LM, Melcher K, Teh BT, Xu HE.
Acta Pharmacol Sin (2014 May) 35:567-84. Abstract/Full Text
Statistical modeling reveals the effect of absolute humidity on dengue in Singapore.
Xu HY, Fu X, Lee LK, Ma S, Goh KT, Wong J, Habibullah MS, Lee GK, Lim TK, Tambyah PA, Lim CL, Ng LC.
PLoS Negl Trop Dis (2014 May) 8:e2805. Abstract/Full Text
Altered regulation of DNA ligase IV activity by aberrant promoter DNA methylation and gene amplification in colorectal cancer.
Kuhmann C, Li C, Kloor M, Salou M, Weigel C, Schmidt CR, Ng LW, Tsui WW, Leung SY, Yuen ST, Becker N, Weichenhan D, Plass C, Schmezer P, Chan TL, Popanda O.
Hum Mol Genet (2014 Apr 15) 23:2043-54. Abstract/Full Text
A mesoscale connectome of the mouse brain.
Oh SW, Harris JA, Ng L, Winslow B, Cain N, Mihalas S, Wang Q, Lau C, Kuan L, Henry AM, Mortrud MT, Ouellette B, Nguyen TN, Sorensen SA, Slaughterbeck CR, Wakeman W, Li Y, Feng D, Ho A, Nicholas E, Hirokawa KE, Bohn P, Joines KM, Peng H, Hawrylycz MJ, Phillips JW, Hohmann JG, Wohnoutka P, Gerfen CR, Koch C, Bernard A, Dang C, Jones AR, Zeng H.
Nature (2014 Apr 10) 508:207-14. Abstract/Full Text
Transcriptional landscape of the prenatal human brain.
Miller JA, Ding SL, Sunkin SM, Smith KA, Ng L, Szafer A, Ebbert A, Riley ZL, Royall JJ, Aiona K, Arnold JM, Bennet C, Bertagnolli D, Brouner K, Butler S, Caldejon S, Carey A, Cuhaciyan C, Dalley RA, Dee N, Dolbeare TA, Facer BA, Feng D, Fliss TP, Gee G, Goldy J, Gourley L, Gregor BW, Gu G, Howard RE, Jochim JM, Kuan CL, Lau C, Lee CK, Lee F, Lemon TA, Lesnar P, McMurray B, Mastan N, Mosqueda N, Naluai-Cecchini T, Ngo NK, Nyhus J, Oldre A, Olson E, Parente J, Parker PD, Parry SE, Stevens A, Pletikos M, Reding M, Roll K, Sandman D, Sarreal M, Shapouri S, Shapovalova NV, Shen EH, Sjoquist N, Slaughterbeck CR, Smith M, Sodt AJ, Williams D, Zöllei L, Fischl B, Gerstein MB, Geschwind DH, Glass IA, Hawrylycz MJ, Hevner RF, Huang H, Jones AR, Knowles JA, Levitt P, Phillips JW, Sestan N, Wohnoutka P, Dang C, Bernard A, Hohmann JG, Lein ES.
Nature (2014 Apr 10) 508:199-206. Abstract/Full Text
Cell-type-based model explaining coexpression patterns of genes in the brain.
Grange P, Bohland JW, Okaty BW, Sugino K, Bokil H, Nelson SB, Ng L, Hawrylycz M, Mitra PP.
Proc Natl Acad Sci U S A (2014 Apr 8) 111:5397-402. Abstract/Full Text
A three-dimensional atlas of human dermal leukocytes, lymphatics, and blood vessels.
Wang XN, McGovern N, Gunawan M, Richardson C, Windebank M, Siah TW, Lim HY, Fink K, Yao Li JL, Ng LG, Ginhoux F, Angeli V, Collin M, Haniffa M.
J Invest Dermatol (2014 Apr) 134:965-974. Abstract/Full Text
Evaluation of bacterial recovery and viability from three different swab transport systems.
Tan TY, Ng LS, Sim DM, Cheng Y, Min MO.
Pathology (2014 Apr) 46:230-3. Abstract/Full Text
CD8 T cells regulate allergic contact dermatitis by modulating CCR2-dependent TNF/iNOS-expressing Ly6C+ CD11b+ monocytic cells.
Chong SZ, Tan KW, Wong FHS, Chua YL, Tang Y, Ng LG, Angeli V, Kemeny DM.
J Invest Dermatol (2014 Mar) 134:666-676. Abstract/Full Text
Incidence of discontinuation of angiotensin-converting enzyme inhibitors due to cough, in a primary healthcare centre in Singapore.
Ng LP, Goh PS.
Singapore Med J (2014 Mar) 55:146-9. Abstract/Full Text
Post community hospital discharge rehabilitation attendance: Self-perceived barriers and participation over time.
Chen AW, Koh YT, Leong SW, Ng LW, Lee PS, Koh GC.
Ann Acad Med Singapore (2014 Mar) 43:136-44. Abstract/Full Text
Synthesis, structure-activity relationships and brain uptake of a novel series of benzopyran inhibitors of insulin-regulated aminopeptidase.
Mountford SJ, Albiston AL, Charman WN, Ng L, Holien JK, Parker MW, Nicolazzo JA, Thompson PE, Chai SY.
J Med Chem (2014 Feb 27) 57:1368-77. Abstract/Full Text
Congenital renal arteriovenous malformation presenting with gross hematuria after a routine jog: a case report.
Dames EL, Ng LG, Tay KH.
J Med Case Rep (2014 Feb 20) 8:65. Abstract/Full Text
Qualitative and quantitative characterization of plasma proteins when incorporating traveling wave ion mobility into a liquid chromatography-mass spectrometry workflow for biomarker discovery: use of product ion quantitation as an alternative data analysis tool for label free quantitation.
Daly CE, Ng LL, Hakimi A, Willingale R, Jones DJ.
Anal Chem (2014 Feb 18) 86:1972-9. Abstract/Full Text
Three new clerodane diterpenes from Polyalthia longifolia var. pendula.
Wu TH, Cheng YY, Chen CJ, Ng LT, Chou LC, Huang LJ, Chen YH, Kuo SC, El-Shazly M, Wu YC, Chang FR, Liaw CC.
Molecules (2014 Feb 13) 19:2049-60. Abstract/Full Text
Rodent Plasmodium-infected red blood cells: imaging their fates and interactions within their hosts.
Claser C, Malleret B, Peng K, Bakocevic N, Gun SY, Russell B, Ng LG, Rénia L.
Parasitol Int (2014 Feb) 63:187-94. Abstract/Full Text
Performance characteristics and clinical predictive value of the string test for detection of hepato-virulent Klebsiella pneumoniae isolated from blood cultures.
Tan TY, Cheng Y, Ong M, Ng LS.
Diagn Microbiol Infect Dis (2014 Feb) 78:127-8. Abstract/Full Text
Plasma C-terminal proEndothelin-1 (CTproET-1) is affected by age, renal function, left atrial size and diastolic blood pressure in healthy subjects.
Bhandari SS, Davies JE, Struck J, Ng LL.
Peptides (2014 Feb) 52:53-7. Abstract/Full Text
Proenkephalin and prognosis after acute myocardial infarction.
Ng LL, Sandhu JK, Narayan H, Quinn PA, Squire IB, Davies JE, Bergmann A, Maisel A, Jones DJ.
J Am Coll Cardiol (2014 Jan 28) 63:280-9. Abstract/Full Text
Worldwide, mortality risk is high soon after initiation of hemodialysis.
Robinson BM, Zhang J, Morgenstern H, Bradbury BD, Ng LJ, McCullough KP, Gillespie BW, Hakim R, Rayner H, Fort J, Akizawa T, Tentori F, Pisoni RL.
Kidney Int (2014 Jan) 85:158-65. Abstract/Full Text
Epidemiology and etiology characteristics of foodborne outbreaks caused by Vibrio parahaemolyticus during 2008-2010 in Guangdong province, China.
Ma C, Deng X, Ke C, He D, Liang Z, Li W, Ke B, Li B, Zhang Y, Ng L, Cui Z.
Foodborne Pathog Dis (2014 Jan) 11:21-9. Abstract/Full Text
Assessment of reproducibility in depletion and enrichment workflows for plasma proteomics using label-free quantitative data-independent LC-MS.
Hakimi A, Auluck J, Jones GD, Ng LL, Jones DJ.
Proteomics (2014 Jan) 14:4-13. Abstract/Full Text
Perivascular macrophages mediate neutrophil recruitment during bacterial skin infection.
Abtin A, Jain R, Mitchell AJ, Roediger B, Brzoska AJ, Tikoo S, Cheng Q, Ng LG, Cavanagh LL, von Andrian UH, Hickey MJ, Firth N, Weninger W.
Nat Immunol (2014 Jan) 15:45-53. Abstract/Full Text
Tse HN, Raiteri L, Wong KY, Ng LY, Yee KS.
Chest (2014 Jan) 145:194-195. Abstract/Full Text
Plasma cortisol and prognosis of patients with acute myocardial infarction.
Jutla SK, Yuyun MF, Quinn PA, Ng LL.
J Cardiovasc Med (Hagerstown) (2014 Jan) 15:33-41. Abstract/Full Text
Pyrethroid resistance in Aedes aegypti larvae (Diptera: Culicidae) from Singapore.
Koou SY, Chong CS, Vythilingam I, Ng LC, Lee CY.
J Med Entomol (2014 Jan) 51:170-81. Abstract/Full Text