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Banner for the 2012 Clinical Research Strategies for Fructose Metabolism Meeting.

Clinical Research Strategies for Fructose Metabolism

Nov. 13 - 14, 2012 Location Contacts
Event Details Agenda

Event Details


This workshop is sponsored by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), the National Heart, Lung, and Blood Institute (NHLBI), the National Institutes of Health (NIH), and the Agriculture Research Service (ARS) of the U.S. Department of Agriculture (USDA).

Meeting Objectives

Consumption of simple sugars (sucrose, glucose, and fructose) currently is estimated at 20 percent of the U.S. diet on average. This coincides with what has been described as an epidemic of obesity and its complications, such as fatty liver, heart disease, and diabetes. Although excess calories are clearly at fault, there is a great deal of public and academic interest in the particular roles, if any, played by simple sugars in the common health problems of Americans. There are some outstanding studies in the literature on the metabolism of fructose and its effects on health outcomes, and many more are being conducted. The current interest, combined with the difficulties of studying a nutrient consumed as a large part of a typical modern diet, led the National Institutes of Health (NIH) to propose a small, 2-day workshop at the NIH Campus in Bethesda, MD, focused on clinical design for studies of fructose and sugar ingestion. Participants from academia, government, advocacy groups, and industry will be invited.

This workshop will showcase studies of the effects of fructose on human whole-body metabolism, energy balance, and obesity as well as on the liver, kidney, and adipose tissue.

Participants will discuss the following:

  • What questions concerning human health remain to be answered?
  • How might clinical trials be designed to provide interpretable data?
  • What are appropriate outcomes measures?

Planning Committee

Peter J. Havel, D.V.M., Ph.D.
Professor, Department of Molecular Biosciences
Department of Nutrition
School of Veterinary Medicine
University of California, Davis

John Bantle, M.D.
Professor of Medicine
Director, Division of Endocrinology and Diabetes
Department of Medicine
University of Minnesota

Elizabeth Parks, Ph.D.
Associate Professor
Center for Human Nutrition
University of Texas Southwestern Medical Center at Dallas

Edward Doo, M.D.
Director, Liver Diseases Research Program
Division of Digestive Diseases and Nutrition

Michael F. Flessner, M.D., Ph.D.
Director of Inflammatory Renal Diseases
Division of Kidney, Urological, and Hematological Diseases

Van S. Hubbard, M.D., Ph.D.
Director, NIH Division of Nutrition Research Coordination
Rear Admiral, U.S. Public Health Service (Ret.)

David M. Klurfeld, Ph.D.
National Program Leader, Human Nutrition
Human Nutrition Research Center
USDA-Agricultural Research Service

Maren R. Laughlin, Ph.D.
Senior Advisor for Integrative Metabolism
Division of Diabetes, Endocrinology, and Metabolic Diseases

Catherine Loria
Epidemiology Branch
Program in Prevention and Population Sciences
Division of Cardiovascular Sciences
National Heart, Lung, and Blood Institute, NIH

Padma Maruvada, Ph.D., M.Sc.
Program Director
Division of Digestive Diseases and Nutrition