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Banner for the 2012 Regulatory Determinants of Hematopoietic Stem Cell Self-Renewal, Lineage Commitment, and Terminal Differentiation: New Insights Meeting

Regulatory Determinants of Hematopoietic Stem Cell Differentiation and Terminal Development: New Insights

Event Details Agenda

Event Details

Meeting Objectives

On February 20, 2012, the Hematology Program of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) at the National Institutes of Health (NIH) will host a one-day workshop on Regulatory Determinants of Hematopoietic Stem Cell Self-Renewal, Lineage Commitment and Terminal Differentiation: New Insights. This state-of-the-science workshop will take place at The American Institute of Architects building in Washington, DC. The objectives of the workshop are to provide an opportunity for research leaders in the field of hematopoietic stem cell (HSC) biology to review and discuss current understanding of how HSC self-renewal, lineage commitment, and terminal differentiation are regulated; to define knowledge gaps and key unanswered questions in these critical aspects of HSC biology; and to define opportunities, directions, and priorities for future research that will address these questions. The program will include presentations by both invited speakers and speakers selected from submitted abstracts, together with poster presentations.

A limited number of travel grants will be made available to registrants whose abstracts are selected for oral presentation at the workshop. Space at the workshop will be limited, so early registration is encouraged. Registrants who submit abstracts for presentation at the workshop will be given preference if the number of registrants exceeds available space. Questions regarding abstract submission and/or registration should be directed to Dr. Wright at daniel.wright@nih.gov.

Workshop Co-organizers and Consultant

Daniel Tenen (Harvard University); Gerd Blobel (University of Pennsylvania); Tannistha Reya (University of California, San Diego); Marc Groudine (University of Washington); Daniel Wright (NIDDK, NIH); Terry Bishop (NIDDK, NIH)


  • Transcriptional regulation of gene activation and silencing relevant to hematopoietic lineage commitment and differentiation
  • Epigenetic determinants of hematopoietic differentiation and terminal development
  • Determinants of HSC self-renewal versus lineage commitment and differentiation in the hematopoietic niche

Invited Speakers

Dan Tenen Bethesda Israel Deaconess/Harvard University

Utpal Banerjee University of California, Los Angeles

Len Zon Children's Hospital Boston/Harvard University

Merav Socolovsky University of Massachusetts

Emery Bresnick University of Wisconsin

Gerd Blobel University of Pennsylvania

Peggy Goodell Baylor University

Indika Rajapakse University of Washington

Frank Rosenbauer Max-Delbrück-Center for Molecular Medicine, Berlin, Germany

Irv Bernstein University of Washington

Tannishtha Reya University of California, San Diego

David Scadden Massachusetts General Hospital/Harvard University

Timm Schroeder Helmholtz Zentrum, Munich, Germany

Paul Frenette Albert Einstein College of Medicine of Yeshiva University

John Chang University of California, San Diego