ApoL1 and Kidney Disease Conference
- Download the Meeting Minutes (PDF, 37.88 KB) .
ApoL1 susceptibility alleles, which are found primarily in African-Americans, are arguably the most important discovery about the pathogenesis of Chronic Kidney Disease over the past 5 years, and among the only known genetic factors contributing to the well-appreciated health disparities in kidney diseases. These variants may explain 70 percent of the excess focal segmental glomerulosclerosis, HIV-associated nephropathy, and hypertensive kidney disease in African Americans.
This conference/workshop will attempt to develop new ideas regarding and pathways to determining how risk alleles lead to disease susceptibility, what kidney and cardiovascular outcomes are associated with these variants, which additional genetic variants or multi-level environmental factors play a role in phenotypic differences, and the possible roles of ApoL1 genotyping in guiding treatment as well as preventive strategies.