Event Details
Agenda
Abstracts
Event Details
Early Stage Investigator Opportunity: See Abstracts Tab
Background
Measurement of body composition during infancy and childhood has important uses in primary and specialty health care settings, clinical research, and national surveys and surveillance. Health care providers can use body composition information to screen for current and future health risks, provide anticipatory guidance, monitor therapeutic progress, and tailor treatment for precision medicine. Researchers can better understand the longitudinal associations between body composition and various health/disease outcomes throughout the lifespan, beginning at birth, and the impact of various obesity prevention and weight management interventions. National reference data for body composition distributions by age, sex, race/ethnicity from survey measurements (e.g., NHANES) can be used for population monitoring and evaluation activities for young children (e.g., WIC clinics, Early Head Start). A number of approaches have been used to estimate or directly measure various aspects of body composition: fat free mass (FFM), fat mass (FM), percent body fat (% BF), total body water (TB H2O), etc. at various ages and include anthropometry (recumbent length, stature, weight, circumferences, skinfold thickness), bioelectrical impedance analysis, air displacement plethysmography; magnetic resonance imaging (MRI), multicompartment models including TBW by deuterium dilution, total body potassium counting, and bone mineral content by dual x-ray absorptiometry (DXA). However, several limitations have been identified across the various measurement procedures that can lead to inaccurate estimates of fat mass or percent BF or prohibit its use in younger children, including prediction equations that tend to be specific to the population from which they were derived (anthropometric measures), inaccuracies due to crying/movement during testing (BOD POD or MRI), exposure to radiation (DXA), and high cost or significant technical examiner expertise (MRI). These limitations and challenges can be considerable for body composition measurement in children from birth to 5 years. There are also presently no approaches that can be used across all ages from birth to adolescence or adulthood for tracking the natural history of obesity or the longitudinal outcomes of intervention research on body composition.
Meeting Objectives
To identify specific needs for research that will help fill existing knowledge gaps and to identify opportunities to improve measurement of body composition components in infants from birth through age 5 years, with a special focus on measures that can be used longitudinally and for evaluation of intervention studies.
Workshop Co-Chairs
Dympna Gallagher, Ed.D.
Professor of Nutritional Medicine
Director of Body Composition Unit
Co-Director, New York Obesity Nutrition Research Center
Division of Endocrinology in Medicine
Columbia University Irving Medical Center, New York, NY
Steven B. Heymsfield, M.D.
Professor
Director of Metabolism and Body Composition Laboratory
Pennington Biomedical Research Center
Louisiana State University, Baton Rouge, LA
NIH Organizing Committee Members
National Institute of Diabetes and Digestive and Kidney Diseases
Robert J. Kuczmarski, Dr.P.H. (Chair)
Voula Osganian, M.D., Sc.D., M.P.H.
Mary Evans, Ph.D.
Susan Yanovski, M.D.
National Heart, Lung, and Blood Institute
Brian Kit, M.D., M.P.H.
NIH Co-Sponsors
NIH Office of Disease Prevention
Eunice Kennedy Shriver National Institute of Child Health and Human Development
Registration Deadline
May 20, 2019
Agenda
May 30, 2019
- 8:15 a.m. – 8:20 a.m.
- Welcoming Remarks
Griffin P. Rodgers, M.D., M.A.C.P., Director of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
- 8:20 a.m. - 8:35 a.m.
- Introduction and Workshop Goals
Robert Kuczmarski, Dr.P.H., Director, Obesity Prevention and Treatment Program Division of Digestive Diseases and Nutrition (DDN), NIDDK
Session 1 Overview of Principals and Assumptions Underlying Body Composition Measurement Approaches
Moderator: Robert Kuczmarski, Dr.P.H.
- 8:35 a.m. - 9:00 a.m.
- Overview of Multi-compartment Approaches (Models): The Foundation for Existing Measurement Approaches
Steven B. Heymsfield, M.D., Pennington Biomedical Research Center, Baton Rouge, LA
- 9:00 a.m. - 9:45 a.m.
- Limitations of Currently Available Methods: Sensitivity and Specificity in Ages 0 to 5 Years
Dympna Gallagher, Ed.D., Columbia University, New York, NY
- 9:45 a.m. - 10:30 a.m.
- Air Displacement (PEAOD and BODPOD) and Dual Energy X-ray Absorptiometry (DXA): Bringing in Practical Perspective, Hands-on Experience, and Limitations
David Fields, Ph.D., University of Oklahoma Health Sciences Center
- 10:30 a.m. - 10:50 a.m.
- Question and Answer Panel
- 10:50 a.m. - 11:15 a.m.
- Morning Break
Session 2 Challenges Associated with Measurement Approaches for Longitudinal Monitoring from Birth to 5 Years
Moderator: Susan Yanovski, M.D., Co-Director, Office of Obesity Research at NIDDK, and Senior Scientific Advisor for Clinical Obesity Research at NIDDK
- 11:15 a.m. - 11:45 a.m.
- Transitioning from Weight-for-Length to Weight-for-Height: Challenges
Cynthia Ogden, Ph.D., Centers for Disease Control and Prevention
- 11:45 a.m. - 12:15 p.m.
- Anthropometry (Skinfolds, Circumferences) and Bioimpedance Analysis: Limitations and Challenges
Shumei Sun, Ph.D., Virginia Commonwealth University, Richmond, VA
- 12:15 p.m. - 12:35 p.m.
- Question and Answer Panel
- 12:35 p.m. - 1:00 p.m.
- Lunch Break
- 1:00 p.m. - 1:30 p.m.
- Poster Session (Atrium): Early Stage Investigators
Session 3 Emerging Measurement Technologies: 0 to 5 Years
Moderator: Mary Evans, Ph.D., Director, Special Projects in Nutrition, Obesity, and Digestive Diseases, DDN, NIDDK
- 1:30 p.m. - 1:50 p.m.
- Quantitative Magnetic Resonance
Aline Andres, Ph.D., University of Arkansas Medical Center
- 1:50 p.m. - 2:10 p.m.
- Optical Imaging
John Shepherd, Ph.D., University of Hawaii Cancer Center
- 2:10 p.m. - 3:10 p.m.
- Are There Biomarkers of Body Composition and Other Approaches to Understanding Early-Life Adiposity?
“Omics,” William Lowe, Ph.D., Northwestern University, Chicago, IL
“Creatine,” Steven Heymsfield, M.D.
"D3Creatine Dilution Method to Assess Muscle Mass," William Evans, Ph.D., University of California, Berkeley
“MRI,” Dympna Gallagher, Ed.D.
- 3:10 p.m. - 3:40 p.m.
- Afternoon Break
- 3:40 p.m. - 4:30 p.m.
- Question and Answer Panel
- 4:30 p.m.
- Summary of Day 1 Proceedings
May 31, 2019
- 8:30 a.m. - 8:40 a.m.
- Opening Remarks and Goals for Day 2
Brian Kit, M.D., M.P.H., Medical Officer, CDR, United States Public Health Service, Epidemiology Branch, National Heart, Lung, and Blood Institute
Session 4 Practical Application for Predicting Obesity and Other Health Outcomes
Moderator: Voula Osganian, M.D., Sc.D., Pediatric Clinical Obesity Program Director, DDN, NIDDK
- 8:40 a.m. - 9:20 a.m.
- Prediction of Metabolic Co-morbidities from Early-Life Adiposity Measures
Emily Oken, M.D., Harvard Pilgrim Health Care Institute
- 9:20 a.m. - 9:50 a.m.
- What Do Clinical Researchers Need to Measure Body Composition in Young Children When Designing Short-term or Longer-term Studies through Adolescence?
Julie Lumeng, M.D., University of Michigan
- 9:50 a.m. - 10:20 a.m.
- Question and Answer Panel
- 10:20 a.m. - 10:40 a.m.
- Morning Break
Session 5 Workshop Outcomes and Products
Moderator: Brian Kit, M.D., M.P.H.
- 10:40 a.m. - 12:10 p.m.
- Panel Discussion Led by Co-Chairs
- 12:10 p.m.
- Brief Closing Remarks
Dympna Gallagher, Ed.D., and Steven Heymsfield, M.D.
Abstracts
To encourage attendance of next-generation researchers and to extend the breadth of information available, a poster session will be held in conjunction with the workshop presentations.
Poster submissions should include a 1-page abstract for the poster session along with a cover letter containing a brief justification explaining why the submitter thinks the focus of the poster presentation would be relevant and contribute to the emphasis of the workshop.
Travel reimbursement will be available to those who are selected and meet the qualifications (Early Stage Investigators, including doctoral and postdoctoral students working in areas of body composition assessment relevant to the topic of the workshop). It is anticipated that up to 20 poster presentations will be accepted.
The poster session will be held in the atrium at 1:00 p.m. on Day 1, May 30, 2019. Presenters are invited to leave posters up all day May 30 but should remove them by 5:00 p.m.
Submission Deadline
March 20, 2019
Submitting Abstracts
All abstracts must be submitted via email to Rachel Pisarski of The Scientific Consulting Group, Inc. Abstract submissions should be no longer than 250 words (not including name and affiliation). Download the Abstract Template (DOCX, 24.67 KB) .
Formatting Requirements
Please follow the instructions below to format an abstract. (Note: Submissions will not be edited for spelling or grammar and will be accepted “as is.”)
- The abstract should be an MS Word document typed single-spaced using Times New Roman font. Everything but the title should be in normal, 12-point font.
- The abstract’s title should be Bold, 16-Point, Title Case font and should clearly represent the nature of the investigation.
- On the line after the title, list the author’s first and last names, degree, affiliation, city, state, and country.
- Separate multiple authors with a semicolon; and underline the primary author’s name (one primary author per abstract).
- Use one blank line between the title and the body of the abstract and between paragraphs.
- The abstract file name should follow this format: LastNameofprimary author_FirstWordOfTitle (e.g., Zucker_Effects).
- Please ensure that your abstract is the correct length and use 1-inch margins.
- Use of standard abbreviations is desirable (e.g., BMI), as well as standard symbols for units of measure (e.g., kg, g, mg, mL, L, and %). Place any special or unusual abbreviations in parentheses after the full word the first time that it appears. Use numerals to indicate numbers except to begin sentences. Do not use subheadings (e.g., Methods, Results).
- Simple tables or graphs may be included; however, they must fit within the designated abstract space of one page.
Acceptance Notification
Participants will be notified if their abstract has been accepted by April 1, 2019.
