Event Details

Meeting Objectives

• Facilitating new collaborations between experts in neuroscience and urology.
• Incorporating technical advances that are well established in other areas of neuroscience and neurology into studies of urogenital regulation and dysfunction.
• Engaging expertise in other areas of neuroscience and neurology to stimulate the development of new approaches needed to define and manipulate peripheral and central nervous system circuits that regulate urogenital function.
• In line with their ongoing impact in other areas of neuroscience, expanding the scope of neuroscience input to understanding urological conditions by involving experts in behavioral neuroscience, developmental neurobiology, neurovascular regulation, systems neuroscience, neural regeneration, and neuroimmunology.
• Discussing priorities and strategies for future neuro-urology research, including identification of major gaps and opportunities, and a target for achievement over a period of the next 5–10 years.

• Poster presentations open to all registrants
• Interdisciplinary collaborations
• Working group discussions to share expertise and develop priorities for the future

Organizing Committee

Janet Keast, The University of Melbourne, Australia
Michelle Southard-Smith, Vanderbilt University
Sanjay Jain, Washington University in St. Louis
Deborah Hoshizaki, NIDDK

Registration Deadline

Agenda

May 19, 2019

6:45 – 7:00 p.m.

Welcome
Dr. Deborah Hoshizaki, NIDDK and Organizing Committee

7:00 – 7:45 p.m.

Plenary Lecture
Connectomics
Dr. Jeff Lichtman, Harvard University

7:45 – 8:15 p.m.

Setting the Scene for Tomorrow: Introduction of Attendees and Summary of Expertise, Interests, and Priorities
Organizers: Dr. Janet Keast, The University of Melbourne, Australia
Dr. Sanjay Jain, Washington University in St. Louis
Dr. Michelle Southard-Smith, Vanderbilt University

8:15 p.m.

Reception and Poster Preview

May 20, 2019

8:30 – 9:00 a.m.

Setting the Scope and Goals of the Meeting
Dr. Rob Star, NIDDK
Dr. Carolyn Best, American Urological Association

Session I: Introduction to Neuro-urology, Gaps, and Challenges

9:00 – 9:30 a.m.

The Clinical Perspective
Dr. Roger Dmochowski, Vanderbilt University

9:30 – 10:00 a.m.

The Basic Science Perspective
Dr. Janet Keast, The University of Melbourne, Australia

10:00 – 10:30 a.m.

Neuro-urology and the Stimulating Peripheral Activity to Relieve Conditions (SPARC) Initiative: New Technologies for Neuromodulation
Dr. Gene Civillico, SPARC Program Manager, NIH

10:30 – 10:50 a.m.

Break

Session II: Sensory Function

10:50 – 11:20 a.m.

Under Pressure: PIEZO Ion Channels in Mechanotransduction
Dr. Kara Marshall, The Scripps Research Institute

11:20 – 11:50 a.m.

Integration of Sensory and Autonomic Function in the Colon, from Lumen to Spinal Cord and Back Again
Dr. Brian Davis, University of Pittsburgh

Session III: Modulation by Non-neuronal Cells

11:50 a.m. – 12:20 p.m.

Neural-Endocrine-Immune Niches in the Airway: Modulating Interconnected Circuits
Dr. Xin Sun, University of California, San Diego

12:20 – 12:50 p.m.

Inflammation-induced Neuroplasticity: Lessons from the Enteric Nervous System
Dr. Gary Mawe, The University of Vermont

12:50 – 2:05 p.m.

Lunch Break

Session IV: Dissecting Complex Behaviors

2:05 – 2:35 p.m.

Brain-Bladder Cross-Talk in Health and Disease
Dr. Rita Valentino, The National Institute on Drug Abuse

2:35 –3 :05 p.m.

Central Control of the Urinary Sphincter
Dr. Lisa Stowers, The Scripps Research Institute

3:05 – 4:50 p.m.

Poster Session and Coffee/Tea Time

4:50 – 6:30 p.m.

Working Group Discussions and Preparation of Presentation to Summarize Outcomes

6:30 p.m.

Dinner (on your own)

May 21, 2019

8:10 – 8:15 a.m.

Overview

Session V: Development and Regeneration of Neural Circuits

8:15 – 9:00 a.m.

Plenary Lecture
Development and Homeostasis of the Enteric Nervous System
Dr. Vassilis Pachnis, Francis Crick Institute, U.K.

9:00 – 9:30 a.m.

When PNS Development Goes Awry: Familial Dysautonomia
Dr. Frances Lefcort, Montana State University

9:30 – 10:00 a.m.

Morphological and Transcriptomic Changes in Pelvic Sensory and Autonomic Circuitry following Spinal Cord Injury
Dr. Matt Ramer, The University of British Columbia, Canada

10:00 – 10:20 a.m.

Break

Session VI: The Neuroscience Toolkit: Understanding and Manipulating Neurons to Understand Biology and Disease

10:20 – 10:50 a.m.

Dissecting Intercellular Communication in the Enteric Nervous System to Understand Gut Health and Disease
Dr. Brian Gulbransen, Michigan State University

10:50 – 11:20 a.m.

Non-voiding Contractions Encode Essential Information for the CNS on Urinary Bladder Fullness
Dr. Mark Nelson, The University of Vermont

11:20 – 11:50 a.m.

Implantable Wireless Optoelectronics for the Study and Treatment of Bladder Pain and Dysfunction
Dr. Rob Gereau, Washington University in St. Louis

11:50 a.m. – 12:20 p.m.

Potential Applications of Single Cell Transcriptomics for Neuro-Urology
Dr. Sanjay Jain, Washington University in St. Louis
Dr. Michelle Southard-Smith, Vanderbilt University

12:20 – 2:00 p.m.

Working Lunch
Reports from Working Groups: Outcomes of the Meeting and Steps for the Future

2:00 p.m.

Adjourn

2:00 – 4:00 p.m.

Steering group to draft meeting report

Travel

Hotel Accommodations

Bethesda North Marriott Hotel & Conference Center
5701 Marinelli Road
Rockville, MD 20852
Telephone: (301) 822-9200
Reserve a Room

Government Room Rate

A block of rooms for participants has been reserved at the hotel. The group rate is $251 per night for single occupancy, plus tax. The reservation cut-off date is April 29, 2019. Room reservations received after this date will be accepted on a space- and rate- available basis.

Reservation Dates

Book your hotel stay for the following dates:

• Arrival: May 19, 2019
• Departure: May 21, 2019