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Preapplication Webinar for Institutional Network Award for Promoting Kidney, Urologic, and Hematologic Research Training—PAR-20-220



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Event Details


On May 28, 2020, the Division of Kidney, Urologic, and Hematologic Diseases (KUH) at the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) issued the Funding Opportunity Announcement (FOA) PAR-20-220 “Institutional Network Award for Promoting Kidney, Urologic, and Hematologic Research Training (U2C-Clinical Trial Not Allowed).”

Per NOT-DK-20-023, NIDDK/KUH has designed and launched this new institutional training program in lieu of NIDDK/KUH participation in PA-20-142 (Parent T32).

In anticipation of questions from the community related to this new program, NIDDK/KUH will be hosting a preapplication webinar on June 16, 2020. Please submit questions in advance to dkkuhtraining@nih.gov by June 12, 2020.

Webinar Details:
Date: Tuesday, June 16, 2020
Time: 12:00 – 2:00 p.m. EDT


NIDDK/KUH staff will provide programmatic information about the FOA and the application review process, as well as answer questions from prospective applicants. The webinar is open to all prospective applicants, although participation in the webinar is not required to submit an application to PAR-20-220. In order to attend the webinar, preregistration is required.

Prospective applicants are highly encouraged to submit their questions regarding the FOA in advance of the webinar to dkkuhtraining@nih.gov by June 12, 2020. Time permitting, participants also will be able to ask questions during the webinar.

After the webinar, an FAQ document will be added to this page. This document may be updated subsequently without additional notice.

Questions and Answers in Response to PA-20-220

Trainees and TL1 Structure

How many trainees are expected to be supported by a single TL1?

  • The TL1 component functions the same as the institutional T32. Your training budget request must include a minimum of five slots each year but may include more—there is no upper limit on the number of supported slots in a given year. For institutions currently supporting multiple T32s that are developing a single U2C/TL1 application, a reasonable starting point for determining the number of proposed training slots would be to add up the number of slots currently supported by the existing T32s in a given year.

With fewer, larger awards (U2C/TL1) being made, will there be a reduction in the number of trainees who will be supported?

  • We do not expect a significant reduction in the total number of research training opportunities (slots). Although there may be fewer U2C/TL1 awards than T32 awards, each U2C/TL1 award will have a higher number of training slots (minimum of 5), compared to the average number of slots per currently active T32 (3.5 slots). In addition, it is worth noting that many of the currently available KUH T32 slots go unfilled every year, resulting in large unobligated (leftover) balances.

Does the TL1 need to support trainees in kidney, urology, AND hematology? How will this integration work?

  • The mission of the FOA is to promote communities that support training across kidney, urologic, and hematologic diseases. However, KUH recognizes that not all institutions (or even Metropolitan Statistical Areas, (MSAs) have equally strong kidney, urologic, and hematologic research communities. Although we encourage our applicants to think creatively, to partner with other neighboring institutions, or to leverage existing resources within a single institution to develop this interdisciplinary community, we understand that not every Institutional Network Award will have equal representation across each discipline. For this reason, the Funding Opportunity Announcement (FOA) does not stipulate how many training slots should be dedicated to kidney, urologic, or hematologic research.
  • Training in such skills as scientific writing, leadership, and entrepreneurship is universally essential for trainees, independent of their chosen field of biomedical research. In addition, building an interdisciplinary community of scientists is an essential part of meeting the demands of the modern workforce.

Is it expected that there would be one combined application that would train both adult and pediatric physician-scientists? Or can an application for the Department of Pediatrics and an application from the Department of Internal Medicine be submitted separately?

  • Only one application per institution is permitted. This application is expected to support trainees across kidney, urology, and hematology research, and it can include both adult- and pediatric-focused research programs, if desired. Separate applications from different departments within a single institution are not permitted.

In one large metropolitan area with multiple institutions, can institution A submit a multi-institution kidney application, institution B submit a multi-institution urology application, and institution C submit a multi-institution hematology application?

  • Although the FOA does not mandate that every application include a kidney, urology, and hematology component, the vision for the U2C/TL1 program is to create multidisciplinary training communities that support research in all NIDDK/KUH-funded scientific areas. Therefore, applications structured as exclusive to any one scientific discipline would be considered of lower programmatic priority.

Can a TL1 support trainees across multiple institutions?

  • Yes. Although only one TL1 award will be issued with each U2C award, the TL1 can support trainees from multiple different institutions.

Can a single TL1 support predoctoral and postdoctoral trainees?

  • Yes, mixed predoctoral and postdoctoral programs are permitted.

Can the networking activities, and other career development activities supported by the U2C portion, include trainees or faculty who receive funding outside of NIDDK/KUH?

  • Yes, networking and other proposed career development activities can involve trainees or faculty who receive funding outside of NIDDK/KUH or who are engaged in research outside of the NIDDK/KUH mission. The immediate goal of the networking core is to create a community of interdisciplinary trainees. At a minimum, this community should bring together trainees across K-, U-, and H-mission area research, including those supported directly by the TL1, in addition to those supported by other mechanisms, such as Fellowships (F), Career Development Awards (K), or Research Experiences (R25). Applicants also are welcome to include other trainees outside of the NIDDK/KUH research areas in these networking efforts. For budget purposes, please justify your requests based on realistic projections of network participants.
  • As a reminder, trainees who are directly supported via the TL1 award must be engaged in research projects that would be considered mission relevant to NIDDK/KUH.

When to Apply

Our current KUH T32 lasts until 2022, and we would have submitted our renewal in 2021. Do we follow that schedule and submit our Institutional Network Awards (U2C/TL1) in 2021?

  • Applicants are welcome to submit at any of the three listed submission dates (having an active T32 does not affect your eligibility to apply for a U2C/TL1). Many institutions may choose to submit an application for a U2C/TL1 award earlier than when they may have planned to submit a T32 renewal to take advantage of the additional resources provided by this new mechanism, and/or to participate in a joint application with other institutions.

I currently have an active KUH T32. I would like to apply for a U2C/TL1 award. Will my application be considered a new application or a renewal?

  • Because PAR-20-220 is a new funding opportunity announcement, all incoming U2C/TL1 awards will be considered new applications, regardless of whether the applicant organization has been or currently holds a KUH T32. Resubmissions (A1s) of a U2C/TL1 application are permitted if the first application (A0) is not selected for funding.

If an Institution currently has an active KUH T32 and a U2C/TL1 application is submitted but not funded, will the KUH T32 still have to be relinquished?

  • KUH T32s will need to be relinquished only if a new U2C/TL1 is awarded. As mandated by NIH policy, NIDDK cannot fund overlapping projects. However, if the U2C/TL1 application is not selected for funding, the active KUH T32 will continue as planned in the original Notice of Award. Resubmissions (A1s) are permitted if the new U2C/TL1 application is not selected for funding.

If a U2C/TL1 is awarded and an active KUH T32 subsequently is relinquished, can the trainees who received support via the T32 continue to receive support via the U2C/TL1?

  • Yes, trainees who received support via a T32 are eligible to finish out their training with support via a TL1. Keep in mind that National Research Service Award (NRSA) aggregate support restrictions still will apply (i.e., a maximum of 3 years of aggregate NRSA support for postdoctoral students, and a maximum of 5 years of aggregate NRSA support for predoctoral students).

When are U2C/TL1 applications due?

  • Applications for the U2C/TL1 awards are due October 14, 2020, October 14, 2021, and October 14, 2022. These new application due dates were published in NOT-DK-20-038.

Multi-Institutional Applications & Metropolitan Statistical Areas

What is a Metropolitan Statistical Area (MSA)?

What if there is only one university within an MSA? Can smaller programs/institutions still submit a competitive application?

  • We understand that not all metropolitan areas have access to the same number of institutions/or resources. For this reason, consolidated applications representing multiple institutions are encouraged—but they are not required.
  • What is driving this encouragement is the attempt to “de-silo” existing training programs, and to move away from the traditional “departmental” view of T32s toward building a stronger, multidisciplinary community of trainees. In past years, multiple KUH T32s have existed within a single metropolitan area (and, often, within a single institution), with very little crosstalk or collaboration between them. The mission at the heart of this FOA is to create a community of trainees and to provide them access to the best resources available in a given institution and/or metropolitan area. How applicants construct a program to best achieve this goal, including if/how to pair up with neighboring institutions, ultimately is up to them. The review criteria listed in PAR-20-220 do not include any sort of quantitative measure of the number of institutions included within a single application. There is no reason, a priori, that smaller institutions can’t submit a competitive application.

Do applicants need to engage ALL institutions within an MSA on a U2C/TL1 application?

  • There are no regulations on the number of institutions within an MSA that need to be included on the application. When considering which institutions to partner with in a single MSA, applicants are asked to identify what would be most beneficial to the community of trainees they intend to support. Often, this means pooling available resources and leveraging opportunities across institutions to provide the best training experience possible. However, the review criteria listed in PAR-20-220 do not include any sort of quantitative measure of the number of institutions included within a single application.

Given the recent expansion of teleconferencing and remote collaborations (with many universities opting for remote-only education this fall), what are the thoughts about awards that cover more than one metropolitan area?

  • Yes, applicants can engage institutions across different MSAs. The application should include a clear justification for this engagement and thoughtful plans for how interactions between participants will be facilitated (i.e., between trainees, or between trainees and training faculty). Applications also should include thoughtful plans for program leadership and communication when engaging multiple institutions, particularly those that are geographically separated.

How many U2C/TL1 applications will be funded?

  • The number of U2C/TL1 awards has not been predetermined. The number of applications selected for funding will depend on the number of competitive, meritorious applications submitted and the final congressional appropriations for each fiscal year. Notably, NIDDK’s/KUH’s commitment to supporting institutional training has not diminished.


Are there any specific instructions for the U2C/TL1 budget?

  • U2C budgets are not limited but need to reflect the actual needs of the proposed project. The budget for the TL1 portion of the application should comply with the NRSA stipend levels and allowable costs. Applicants requesting $500,000 or more in direct costs in any year must submit a proposed budget and justification memo to the scientific program contact (Victoria Spruance, PhD) at least 6 weeks before submitting the application. We anticipate many U2C/TL1 applications will exceed this budget threshold.

Can Principal Investigators (PIs) request salary support through the U2C/TL1? What about Core Directors or Mentors?

  • As a major benefit of the new Institutional Network Awards, salary support can be requested via the U2C funding mechanism. We recognize that the Project Director (PD)/PIs of the U2C will invest significant time and energy in creating and managing an Institutional Network Award that merits financial support. This support should be limited to the PD/PI of the overall U2C, and in some cases, Core Directors who will be involved heavily in the Institutional Network Award Activities. Of course, appropriate justification should be included with all budget proposals and will be subject to peer review. Mentors will not receive salary support via this mechanism.

Is PI effort for the TL1 allowable in the TL1 budget, or should that be funded through the U2C?

  • As the TL1 award is subject to NRSA budget restrictions, PI effort should be requested via the U2C budget.

Is the indirect cost rate for the TL1 component set at 8%? What is the indirect cost rate for the U2C component?

  • As an NRSA-funded mechanism, the indirect costs for the TL1 award are capped at 8%. The indirect cost rate for the U2C component will be the standard negotiated rate for the applicant organization.

Do we need to include plans/budget for hosting an annual meeting? Will every U2C/TL1 awardee be expected to host a meeting?

  • To cultivate the K-, U-, and H-training community, all trainees supported by the U2C/TL1 awards across the country, in addition to PDs and Mentors, will be invited to attend an annual meeting. The responsibility of hosting this meeting will rotate among awarded institutions.
  • Therefore, each applicant (i.e., applicant institution) should propose plans for hosting the annual meeting and incorporate the associated costs into their proposed budgets. Ultimately, as the U2C awards will be Cooperative Agreements, all awarded institutions will work closely with NIDDK to finalize plans for how, when, and where each annual meeting will take place. It is possible there may be more U2C/TL1 awardees than there are annual meetings in a given project period, in which case some awarded institutions may not end up hosting a meeting at all. These types of logistical details will be determined once awards are made and Cooperative Agreements are formed.
  • As a side note, the number of annual meetings in a project period is not meant to correlate with the number of awardees. The number of U2C/TL1 awards ultimately will be dependent upon available funds each fiscal year and the number of applications that are submitted and peer reviewed meritoriously.

PI/PD Eligibility

Do all PDs/PIs associated with a U2C/TL1 application need to be NIDDK-funded investigators?

  • There is an expectation that the overall PDs/PIs of the U2C and TL1 awards are established investigators with active research portfolios supported by NIDDK/KUH. This requirement does NOT apply to other investigators associated with each U2C/TL1—including those who may serve as Core Directors, Mentors, Co-Sponsors, or other Faculty. That said, all trainees directly supported by the TL1 award must be engaged in KUH-mission area research.

Do the PD/PIs for the U2C award need to be different from the PD/PIs for the TL1 award? Are there separate applications for the U2C and TL1 components?

  • The proposed PD/PI for the U2C award should be different from the PD/PIs for the TL1 award. Although there is a single application for the combined U2C/TL1, these components will be separated upon award. Each component will maintain its own budget.

Event Logistics


Registration Closed
Registration ended



Program Contacts
Victoria Spruance, Ph.D.
T: 301-827-5091

Tracy Rankin, Ph.D., M.P.H.
T: 301-594-4748