Technologies to Optimize Kidneys for Transplant

Event Details

The number of donor kidneys available for people with end-stage renal disease (ESRD) is currently insufficient. This workshop will focus on the scientific and technical barriers to enhanced evaluation, preservation, repair, and optimization of donor kidneys to improve organ utilization. The workshop will bring together experts from a wide range of disciplines to identify challenges and opportunities, stimulate multidisciplinary collaboration, and accelerate research.

This kick-off virtual event will be held to stimulate interest in and prioritize topics for a face-to-face conference that will be scheduled when feasible.

Home page committee:

Kevin Abbott, M.D., M.P.H. (NIDDK)
Eric Brunskill, Ph.D. (NIDDK)
Kelvin Brockbank, Ph.D. (Clemson)
Daniel Gossett, Ph.D. (NIDDK)
Chris Ketchum, Ph.D. (NIDDK)
Sandy Martin, Ph.D. (University of Colorado-AMC)
Dianne McKay, M.D. (Scripps)
Anna Sadusky, Ph.D. (NIDDK)
Ivonne Schulman, M.D. (NIDDK)
Gregory Tietjen, Ph.D. (Yale)
Mehmet Toner, Ph.D. (Massachusetts General Hospital)

Registration Deadline

July 13, 2021

Agenda

July 14, 2021

11:00 a.m. – 11:05 a.m.

Welcoming Remarks and Meeting Charge
Robert Star, M.D., National Institute of Diabetes and Digestive and Kidney Diseases

11:05 a.m. – 11:25 a.m.

An Epidemiological Perspective on Issues in Kidney Transplant, Including Disparities
Tanjala Purnell, Ph.D., M.P.H., Johns Hopkins Schools of Public Health and Medicine

11:25 a.m. – 11:35 a.m.

Questions

Scientific Session 1: Reducing Discard by Improved Evaluation

11:35 a.m. – 11:55 a.m.

A Deep Learning Model to Improve Pathologist Interpretation of Donor Kidney Biopsies
Joseph Gaut, M.D., Ph.D., Washington University School of Medicine in St. Louis

11:55 a.m. – 12:15 p.m.

Organ Function Assessment on Machine Perfusion
Sarah Hosgood, Ph.D., University of Cambridge

12:15 p.m. – 12:25 p.m.

Discussion

12:25 p.m. – 12:30 p.m.

Break

Scientific Session 2: Preventing Injury during Transit and in Storage

12:30 p.m. – 12:50 p.m.

How Preservation Will Impact Kidney Transplant Paradigms
Dianne McKay, M.D., The Scripps Research Institute

12:50 p.m. – 1:10 p.m.

Cryobiology and Stabilization of Vascular Organs
Korkut Uygun, Ph.D., Massachusetts General Hospital

1:10 p.m. – 1:30 p.m.

Renal Adaptation During Hibernation (Ground Squirrels and Other Species)
Alkesh Jani, M.D., University of Colorado-AMC

1:30 p.m. – 1:40 p.m.

Discussion

1:40 p.m. – 1:45 p.m.

Break

Scientific Session 3: Optimizing Viability and Function and Promoting Repair

1:45 p.m. – 2:05 p.m.

Normothermic Machine Perfusion of Human Kidneys: A Platform for Targeted Therapies
Gregory Tietjen, Ph.D., Yale University

2:05 p.m. – 2:25 p.m.

Mesenchymal Stem Cells and Kidney Transplant
LaTonya Hickson, M.D., Mayo Clinic

2:25 p.m. – 2:45 p.m.

Acomys cahrinus: A New Paradigm for Kidney Wound Repair
Daryl Okamura, M.D., University of Washington

2:45 p.m. – 2:55 p.m.

Discussion

2:55 p.m.

Adjournment