Min Li, Ph.D.
Photo of Min Li
Scientific Focus Areas: Molecular Biology and Biochemistry, Structural Biology


A selection of recent and significant publications can be viewed below.

Human Three Prime Repair Exonuclease 1 Promotes HIV-1 Integration by Preferentially Degrading Unprocessed Viral DNA.
Davids BO, Balasubramaniam M, Sapp N, Prakash P, Ingram S, Li M, Craigie R, Hollis T, Pandhare J, Dash C.
J Virol (2021 Aug 10) 95:e0055521. Abstract/Full Text
Retroviral integrase: Structure, mechanism, and inhibition.
Passos DO, Li M, Craigie R, Lyumkis D.
Enzymes (2021) 50:249-300. Abstract/Full Text
A Peptide Derived from Lens Epithelium-Derived Growth Factor Stimulates HIV-1 DNA Integration and Facilitates Intasome Structural Studies.
Li M, Chen X, Wang H, Jurado KA, Engelman AN, Craigie R.
J Mol Biol (2020 Mar 27) 432:2055-2066. Abstract/Full Text
Structural basis for strand-transfer inhibitor binding to HIV intasomes.
Passos DO, Li M, Jóźwik IK, Zhao XZ, Santos-Martins D, Yang R, Smith SJ, Jeon Y, Forli S, Hughes SH, Burke TR Jr, Craigie R, Lyumkis D.
Science (2020 Feb 14) 367:810-814. Abstract/Full Text
Cryo-EM structures and atomic model of the HIV-1 strand transfer complex intasome.
Passos DO, Li M, Yang R, Rebensburg SV, Ghirlando R, Jeon Y, Shkriabai N, Kvaratskhelia M, Craigie R, Lyumkis D.
Science (2017 Jan 6) 355:89-92. Abstract/Full Text
Outer domains of integrase within retroviral intasomes are dispensible for catalysis of DNA integration.
Li M, Lin S, Craigie R.
Protein Sci (2016 Feb) 25:472-8. Abstract/Full Text
Engineered hyperactive integrase for concerted HIV-1 DNA integration.
Li M, Jurado KA, Lin S, Engelman A, Craigie R.
PLoS One (2014) 9:e105078. Abstract/Full Text
Retroviral intasomes: progress and questions.
Li M, Craigie R.
Structure (2012 Nov 7) 20:1804-5. Abstract/Full Text
DNA requirements for assembly and stability of HIV-1 intasomes.
Li M, Ivanov V, Mizuuchi M, Mizuuchi K, Craigie R.
Protein Sci (2012 Feb) 21:249-57. Abstract/Full Text
Nucleoprotein complex intermediates in HIV-1 integration.
Li M, Craigie R.
Methods (2009 Apr) 47:237-42. Abstract/Full Text
Retroviral DNA integration: reaction pathway and critical intermediates.
Li M, Mizuuchi M, Burke TR Jr, Craigie R.
EMBO J (2006 Mar 22) 25:1295-304. Abstract/Full Text
Processing of viral DNA ends channels the HIV-1 integration reaction to concerted integration.
Li M, Craigie R.
J Biol Chem (2005 Aug 12) 280:29334-9. Abstract/Full Text
Last Reviewed June 2023