John R. Lloyd, Ph.D.


A selection of recent and significant publications can be viewed below.

Microbial ecology of arsenic-mobilizing Cambodian sediments: lithological controls uncovered by stable-isotope probing.
Héry M, Rizoulis A, Sanguin H, Cooke DA, Pancost RD, Polya DA, Lloyd JR.
Environ Microbiol (2015 Jun) 17:1857-69. Abstract/Full Text
Microbial degradation of isosaccharinic acid at high pH.
Bassil NM, Bryan N, Lloyd JR.
ISME J (2015 Feb) 9:310-20. Abstract/Full Text
Older patients have the most to gain from orthopaedic enhanced recovery programmes.
Starks I, Wainwright TW, Lewis J, Lloyd J, Middleton RG.
Age Ageing (2014 Sep) 43:642-8. Abstract/Full Text
Say no to DMSO: dimethylsulfoxide inactivates cisplatin, carboplatin, and other platinum complexes.
Hall MD, Telma KA, Chang KE, Lee TD, Madigan JP, Lloyd JR, Goldlust IS, Hoeschele JD, Gottesman MM.
Cancer Res (2014 Jul 15) 74:3913-22. Abstract/Full Text
Design, synthesis and evaluation of phenethylaminoheterocycles as K(v)1.5 inhibitors.
Johnson JA, Xu N, Jeon Y, Finlay HJ, Kover A, Conder ML, Sun H, Li D, Levesque P, Hsueh MM, Harper TW, Wexler RR, Lloyd J.
Bioorg Med Chem Lett (2014 Jul 15) 24:3018-22. Abstract/Full Text
Investigation of a link between raised levels of pepsinogen in blood as a mediator of in-vitro clot lysis in acid and a cause of abnormal factor XIII screening tests.
Duncan EM, Dale BJ, Lloyd JV.
Blood Coagul Fibrinolysis (2014 Jun) 25:340-8. Abstract/Full Text
Action is needed to tackle current public health threats.
Watson MC, Lloyd J.
BMJ (2014 Apr 14) 348:g2721. Abstract/Full Text
Inhibition of sulfate reducing bacteria in aquifer sediment by iron nanoparticles.
Kumar N, Omoregie EO, Rose J, Masion A, Lloyd JR, Diels L, Bastiaens L.
Water Res (2014 Mar 15) 51:64-72. Abstract/Full Text
Meropenem inhibits D,D-carboxypeptidase activity in Mycobacterium tuberculosis.
Kumar P, Arora K, Lloyd JR, Lee IY, Nair V, Fischer E, Boshoff HI, Barry CE 3rd.
Mol Microbiol (2012 Oct) 86:367-81. Abstract/Full Text
Geographic variability and anti-staphylococcal activity of the chrysophaentins and their synthetic fragments.
Keffer JL, Hammill JT, Lloyd JR, Plaza A, Wipf P, Bewley CA.
Mar Drugs (2012 May) 10:1103-25. Abstract/Full Text
Discovery and synthesis of namalide reveals a new anabaenopeptin scaffold and peptidase inhibitor.
Cheruku P, Plaza A, Lauro G, Keffer J, Lloyd JR, Bifulco G, Bewley CA.
J Med Chem (2012 Jan 26) 55:735-42. Abstract/Full Text
Peptide fragmentation by corona discharge induced electrochemical ionization.
Lloyd JR, Hess S.
J Am Soc Mass Spectrom (2010 Dec) 21:2051-61. Abstract/Full Text
Multivalent dendrimeric and monomeric adenosine agonists attenuate cell death in HL-1 mouse cardiomyocytes expressing the A(3) receptor.
Keene AM, Balasubramanian R, Lloyd J, Shainberg A, Jacobson KA.
Biochem Pharmacol (2010 Jul 15) 80:188-96. Abstract/Full Text
Chrysophaentins A-H, antibacterial bisdiarylbutene macrocycles that inhibit the bacterial cell division protein FtsZ.
Plaza A, Keffer JL, Bifulco G, Lloyd JR, Bewley CA.
J Am Chem Soc (2010 Jul 7) 132:9069-77. Abstract/Full Text
Mutremdamide A and koshikamides C-H, peptide inhibitors of HIV-1 entry from different Theonella species.
Plaza A, Bifulco G, Masullo M, Lloyd JR, Keffer JL, Colin PL, Hooper JN, Bell LJ, Bewley CA.
J Org Chem (2010 Jul 2) 75:4344-55. Abstract/Full Text
Structural basis of G protein-coupled receptor-G protein interactions.
Hu J, Wang Y, Zhang X, Lloyd JR, Li JH, Karpiak J, Costanzi S, Wess J.
Nat Chem Biol (2010 Jul) 6:541-8. Abstract/Full Text
Paltolides A--C, anabaenopeptin-type peptides from the palau sponge Theonella swinhoei.
Plaza A, Keffer JL, Lloyd JR, Colin PL, Bewley CA.
J Nat Prod (2010 Mar 26) 73:485-8. Abstract/Full Text
Celebesides A-C and theopapuamides B-D, depsipeptides from an Indonesian sponge that inhibit HIV-1 entry.
Plaza A, Bifulco G, Keffer JL, Lloyd JR, Baker HL, Bewley CA.
J Org Chem (2009 Jan 16) 74:504-12. Abstract/Full Text
Enhanced A3 adenosine receptor selectivity of multivalent nucleoside-dendrimer conjugates.
Klutz AM, Gao ZG, Lloyd J, Shainberg A, Jacobson KA.
J Nanobiotechnology (2008 Oct 23) 6:12. Abstract/Full Text