Publications

A selection of recent and significant publications can be viewed below.

A simple and cost-effective protocol for high-yield expression of deuterated and selectively isoleucine/leucine/valine methyl protonated proteins in Escherichia coli grown in shaker flasks.: Cai M, Huang Y, Lloyd J, Craigie R, Clore GM.; J Biomol NMR (2021 Mar) 75:83-87. Abstract/Full Text
Chlorcyclizine Inhibits Viral Fusion of Hepatitis C Virus Entry by Directly Targeting HCV Envelope Glycoprotein 1.: Hu Z, Rolt A, Hu X, Ma CD, Le DJ, Park SB, Houghton M, Southall N, Anderson DE, Talley DC, Lloyd JR, Marugan JC, Liang TJ.; Cell Chem Biol (2020 Jul 16) 27:780-792.e5. Abstract/Full Text
Structure-Based Design, Synthesis by Click Chemistry and in Vivo Activity of Highly Selective A(3) Adenosine Receptor Agonists.: Tosh DK, Paoletta S, Chen Z, Crane S, Lloyd J, Gao ZG, Gizewski ET, Auchampach JA, Salvemini D, Jacobson KA.; Medchemcomm (2015) 6:555-563. Abstract/Full Text
Say no to DMSO: dimethylsulfoxide inactivates cisplatin, carboplatin, and other platinum complexes.: Hall MD, Telma KA, Chang KE, Lee TD, Madigan JP, Lloyd JR, Goldlust IS, Hoeschele JD, Gottesman MM.; Cancer Res (2014 Jul 15) 74:3913-22. Abstract/Full Text
Meropenem inhibits D,D-carboxypeptidase activity in Mycobacterium tuberculosis.: Kumar P, Arora K, Lloyd JR, Lee IY, Nair V, Fischer E, Boshoff HI, Barry CE 3rd.; Mol Microbiol (2012 Oct) 86:367-81. Abstract/Full Text
Geographic variability and anti-staphylococcal activity of the chrysophaentins and their synthetic fragments.: Keffer JL, Hammill JT, Lloyd JR, Plaza A, Wipf P, Bewley CA.; Mar Drugs (2012 May) 10:1103-1125. Abstract/Full Text
Discovery and synthesis of namalide reveals a new anabaenopeptin scaffold and peptidase inhibitor.: Cheruku P, Plaza A, Lauro G, Keffer J, Lloyd JR, Bifulco G, Bewley CA.; J Med Chem (2012 Jan 26) 55:735-42. Abstract/Full Text
Peptide fragmentation by corona discharge induced electrochemical ionization.: Lloyd JR, Hess S.; J Am Soc Mass Spectrom (2010 Dec) 21:2051-61. Abstract/Full Text
Multivalent dendrimeric and monomeric adenosine agonists attenuate cell death in HL-1 mouse cardiomyocytes expressing the A(3) receptor.: Keene AM, Balasubramanian R, Lloyd J, Shainberg A, Jacobson KA.; Biochem Pharmacol (2010 Jul 15) 80:188-96. Abstract/Full Text
Chrysophaentins A-H, antibacterial bisdiarylbutene macrocycles that inhibit the bacterial cell division protein FtsZ.: Plaza A, Keffer JL, Bifulco G, Lloyd JR, Bewley CA.; J Am Chem Soc (2010 Jul 7) 132:9069-77. Abstract/Full Text
Mutremdamide A and koshikamides C-H, peptide inhibitors of HIV-1 entry from different Theonella species.: Plaza A, Bifulco G, Masullo M, Lloyd JR, Keffer JL, Colin PL, Hooper JN, Bell LJ, Bewley CA.; J Org Chem (2010 Jul 2) 75:4344-55. Abstract/Full Text
Structural basis of G protein-coupled receptor-G protein interactions.: Hu J, Wang Y, Zhang X, Lloyd JR, Li JH, Karpiak J, Costanzi S, Wess J.; Nat Chem Biol (2010 Jul) 6:541-8. Abstract/Full Text
Paltolides A--C, anabaenopeptin-type peptides from the palau sponge Theonella swinhoei.: Plaza A, Keffer JL, Lloyd JR, Colin PL, Bewley CA.; J Nat Prod (2010 Mar 26) 73:485-8. Abstract/Full Text
Celebesides A-C and theopapuamides B-D, depsipeptides from an Indonesian sponge that inhibit HIV-1 entry.: Plaza A, Bifulco G, Keffer JL, Lloyd JR, Baker HL, Bewley CA.; J Org Chem (2009 Jan 16) 74:504-12. Abstract/Full Text
Enhanced A3 adenosine receptor selectivity of multivalent nucleoside-dendrimer conjugates.: Klutz AM, Gao ZG, Lloyd J, Shainberg A, Jacobson KA.; J Nanobiotechnology (2008 Oct 23) 6:12. Abstract/Full Text

Last Reviewed February 2024