- Staff Scientist, NIH, 2011-present
- Contractor, Animal Biologist, NIH, 2011
- Research Fellow, NIH, 2009-2010
- Postdoctoral Fellow, NIH, 2004-2008
- Associate Professor, West China Center of Medical Sciences, Sichuan University, Chengdu, Sichuan, China, 2003
- Lecturer, Associate Professor, West China University of Medical Sciences, 1995-2001
- Visiting Scholar, Radbound University Nijmegen (Dutch: Radbound Universiteit Nijmegan, formerly Katholieke Universiteit Nijmegen), 1994-1995
- Ph.D., Sichuan University, 2003
- Visiting Ph.D. Student, Weizmann Institute of Sciences, Rehovot, Israel, 2001-2002
- Master of Medicine, West China Center of Medical Sciences, Sichuan University, Chengdu, Sichuan, China, 1989
- M.D., Luzhou Medical College, Luzhou, Sichuan, China, 1983
The goal of our research is to make advances in the treatment of diabetes and obesity.
I conduct research to elucidate the mechanisms underlying energy homeostasis.
Applying our Research
With a higher prevalence of diabetes and obesity worldwide, treatment for these morbidities is imperative. Knowledge obtained from mouse experimentation in our research will generate hypotheses. These hypotheses will be followed upon in a clinical setting, and will ultimately advance the treatment of diabetes and obesity.
Need for Further Study
The regulation of energy homeostasis is not fully understood, and measures to treat diabetes and obesity are limited. Knowledge from mouse models would be helpful to further explore these areas.
- Adenosine A3 agonists reverse neuropathic pain via T cell-mediated production of IL-10.
- Durante M, Squillace S, Lauro F, Giancotti LA, Coppi E, Cherchi F, Di Cesare Mannelli L, Ghelardini C, Kolar G, Wahlman C, Opejin A, Xiao C, Reitman ML, Tosh DK, Hawiger D, Jacobson KA, Salvemini D.
- J Clin Invest (2021 Apr 1) 131. Abstract/Full Text
- Activation of neuronal adenosine A1 receptors causes hypothermia through central and peripheral mechanisms.
- Province HS, Xiao C, Mogul AS, Sahoo A, Jacobson KA, Piñol RA, Gavrilova O, Reitman ML.
- PLoS One (2020) 15:e0243986. Abstract/Full Text
Research in Plain Language
My research involves using mouse models to understand metabolic rate regulation, body temperature regulation, and drug treatments for obesity.