Even the most sophisticated individual approaches for obesity prevention and treatment are less likely to be effective in an environment that is obesity-promoting.
Experts Susan Z. Yanovski, MD, from the National Institute of Diabetes and Digestive and Kidney Diseases, and Jack Yanovski, MD, PhD, from the Division of Intramural Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, discuss how factors that vary among people—including environmental, psychosocial, cultural, economic, and genetic factors—may lead to differences in susceptibility to obesity or in response to weight management treatment. In their Viewpoint article, they emphasize that there is rarely a single gene alteration that leads to obesity, but rather it results from multiple underlying susceptibility factors acting in concert with an obesity-promoting environment. Scientists are still in the early stages of using personalized approaches and interventions to reduce obesity and related problems such as diabetes. Learn more here: Toward Precision Approaches for the Prevention and Treatment of Obesity