Definition & Facts of Kidney Infection (Pyelonephritis)
What is a kidney infection?
A kidney infection is a type of urinary tract infection (UTI). Most kidney infections are caused by bacteria or viruses that first infect your lower urinary tract, usually your bladder. Then, the infection moves upstream to one or both of your kidneys, which are part of the upper urinary tract.
In some cases, you can get a kidney infection after surgery if bacteria enter your body during the procedure and travel through your blood to the kidneys.
Your body has ways to defend against infections in the urinary tract. For example, urine normally flows one way from your kidneys to your bladder. Viruses or bacteria that enter are flushed out by urinating. This one-way flow of urine usually prevents an infection in your urinary tract. Learn more about your urinary tract and how it works.
Sometimes your body’s defenses fail and bacteria or viruses cause a UTI in the bladder. If you have symptoms of a bladder infection, see a health care professional. You may need treatment to prevent the infection from spreading to your kidneys. Kidney infections are often very painful and can cause serious health problems.
Does kidney infection have another name?
Yes, the medical term for kidney infection is pyelonephritis.
How common are kidney infections?
Kidney infections cause most of the 100,000 hospital visits for UTIs in the United States each year.1
Who is more likely to develop a kidney infection?
You are more likely to develop a kidney infection if you
- Are a woman2
- have a UTI in the bladder.
- had a UTI during the past 12 months.
- are pregnant. Scientists think that hormonal changes and shifts in the position of the urinary tract during pregnancy make it easier for bacteria to travel to the kidneys and cause infection.
- have a problem in your urinary tract that blocks or changes the normal flow of urine. The flow of urine may be blocked if you have a defect in the structure of your urinary tract, such as a narrowed urethra, an enlarged prostate, or a kidney stone.
- have vesicoureteral reflux (VUR), which is when urine can back up, or reflux, into one or both kidneys. Health care professionals most commonly diagnose VUR in children.3
- have diabetes or problems with your body’s immune, or natural defense, system.
- have a spinal cord injury or nerve damage around the bladder.
- have trouble emptying your bladder completely, called urinary retention.
What are the complications of kidney infections?
In rare cases, kidney infections may cause
- high blood pressure
- kidney failure
- permanent kidney scars, called renal scarring, which can lead to chronic kidney disease
Your chance of a complication is slightly greater if you have
- kidney disease from other causes
- a problem with the structure of your urinary tract
- repeated episodes of kidney infection
Complications from a kidney infection are rare if a health care professional prescribes antibiotics to treat your infection.
This content is provided as a service of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), part of the National Institutes of Health. The NIDDK translates and disseminates research findings through its clearinghouses and education programs to increase knowledge and understanding about health and disease among patients, health professionals, and the public. Content produced by the NIDDK is carefully reviewed by NIDDK scientists and other experts.
The NIDDK would like to thank:
Ann E. Stapleton, MD, FIDSA, FACP, University of Washington School of Medicine