News Release
Oct. 30, 2024
Young people with severe obesity who underwent weight-loss surgery at age 19 or younger continued to see sustained weight loss and resolution of common obesity-related comorbidities 10 years later, according to results from a large clinical study funded by the National Institutes of Health (NIH).
News Release
Oct. 28, 2024
A study from researchers at National Institutes of Health (NIH) and their collaborators revealed a significant genetic risk factor for kidney disease in people from Ghana and Nigeria. Their study demonstrated that having just one risk variant in a gene known as APOL1 can significantly increase the risk of developing kidney disease. APOL1 is important for the immune system and variants of the gene are linked to increased risk of chronic kidney disease.
News Release
Oct. 10, 2024
Infection from COVID-19 appeared to significantly increase the risk of heart attack, stroke, and death for up to three years among unvaccinated people early in the pandemic when the original SARS-CoV-2 virus strain emerged, according to a National Institutes of Health (NIH)-supported study. The findings, among people with or without heart disease, confirm previous research showing an associated higher risk of cardiovascular events after a COVID-19 infection but are the first to suggest the heightened risk might last up to three years following initial infection, at least among people infected in the first wave of the pandemic.
News Release
Oct. 9, 2024
The National Institutes of Health has launched a nationwide consortium to address the dramatic rise in youth diagnosed with type 2 diabetes over the past two decades, a trend that is expected to continue. The effort aims to advance understanding of the biologic, social, and environmental drivers of youth-onset type 2 diabetes, with the goals of determining which children are at highest risk for developing the disease and how to better prevent, screen for, and manage type 2 diabetes in young people.
News Release
Sept. 17, 2024
Adults who use the prescription drug metformin to treat their type 2 diabetes have a lower risk of developing long COVID or dying after a COVID-19 infection than people with diabetes who take other anti-diabetes medications, according to a large study supported by the National Institutes of Health.
News Release
April 4, 2024
Researchers have shown that dangerous cysts, which form over time in polycystic kidney disease (PKD), can be prevented by a single normal copy of a defective gene. This means the potential exists that scientists could one day tailor a gene therapy to treat the disease. They also discovered that a type of drug, known as a glycoside, can sidestep the effects of the defective gene in PKD. The discoveries could set the stage for new therapeutic approaches to treating PKD, which affects millions worldwide.
News Release
Feb. 27, 2024
People with type 2 diabetes who underwent bariatric surgery achieved better long-term blood glucose control compared to people who received medical management plus lifestyle interventions according to a new study supported by the National Institutes of Health.
News Release
Jan. 30, 2024
Researchers at the National Institutes of Health observed rapid and distinct immune system changes in a small study of people who switched to a vegan or a ketogenic (also called keto) diet. Scientists closely monitored various biological responses of people sequentially eating vegan and keto diets for two weeks, in random order.
News Release
Jan. 10, 2024
Diabetes in America is the NIDDK’s compilation and assessment of epidemiologic, public health, clinical research, and clinical trial data focused on diabetes. This updated resource, developed by researchers at NIDDK and leading diabetes experts from around the country and world, is a one-stop source for crucial scientific information on diabetes, its complications and treatment, health care utilization, and diabetes prevention in the United States.
News Release
July 19, 2023
A study funded by the NIH created the most comprehensive atlas of the human kidney to advance progress in understanding and treating kidney disease. The Kidney Tissue Atlas marks an important milestone for the multicenter study, called the Kidney Precision Medicine Project (KPMP), which began in 2017 with the aim of improving treatment for kidney disease.
News Release
April 27, 2023
A study supported by the National Institutes of Health found that people who experienced acute kidney injury (AKI) during a hospitalization, including those admitted with AKI or who developed AKI in the hospital, were more likely to revisit the hospital or die shortly after discharge, compared to people hospitalized without AKI. AKI is a sudden loss of kidney function that usually lasts for a short time. The research, funded by NIH’s National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), was published in the American Journal of Kidney Diseases.
News Release
March 15, 2023
Artificial pancreas technology improved blood glucose control in young children between ages 2 and 6 with type 1 diabetes, according to the results of the Pediatric Artificial Pancreas (PEDAP) Trial, a 13-week randomized controlled trial conducted at three pediatric diabetes centers across the United States.
News Release
Feb. 7, 2023
Findings from NIH-supported clinical trial showed early treatment of diabetes slows progression to severe disease, but it did not improve visual acuity compared with treating more severe disease once it developed.
News Release
Jan. 5, 2023
A research team supported by the National Institutes of Health has developed a new approach to better understand the biology of polycystic kidney disease (PKD), and often-life-threatening genetic disorder that affects millions worldwide. Scientists combined two ways to model the disorder — organ-in-a-dish and organ-on-a-chip technologies — to show the role of glucose, a sugar commonly found in blood, in forming PKD cysts.
News Release
Dec. 29, 2022
The number of young people under age 20 with diabetes in the United States is likely to increase more rapidly in future decades, according to a new modeling study published today in Diabetes Care.
News Release
Nov. 2, 2022
Taking a personalized approach to kidney disease screening for people with type 1 diabetes (T1D) may reduce the time that chronic kidney disease (CKD) goes undetected, according to a new analysis performed by the Epidemiology of Diabetes Interventions and Complications study group, which is funded by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), part of the National Institutes of Health. The finding, published in Diabetes Care, provides the basis for the first evidence-based kidney screening model for people with T1D.
News Release
Sept. 28, 2022
A device known as a bionic pancreas, which uses next-generation technology to automatically deliver insulin, was more effective at maintaining blood glucose (sugar) levels within normal range than standard-of-care management among people with type 1 diabetes, a new multicenter clinical trial has found.
News Release
Sept. 21, 2022
In a large clinical trial that directly compared four drugs commonly used to treat type 2 diabetes, researchers found that insulin glargine and liraglutide performed the best of four medications approved by the U.S. Food and Drug Administration to maintain blood glucose levels in the recommended range.
News Release
July 14, 2022
NIH-funded clinical trial finds that starting with a cheaper drug and switching to a more expensive drug as needed leads to good vision outcomes in diabetic macular edema.
News Release
Jan. 20, 2022
The National Institutes of Health is awarding $170 million over five years, pending the availability of funds, to clinics and centers across the country for a new study that will develop algorithms to predict individual responses to food and dietary routines.
News Release
Jan. 18, 2022
The National Institutes of Health has launched the first phase of the Neuromod Prize, a $9.8 million competition to accelerate the development of neuromodulation therapies — targeted treatments that adjust nerve activity to improve organ function.
News Release
Dec. 21, 2021
An intervention shown to help first-time parents prevent childhood obesity has shown spillover effects in second-born children as well, even without further training for the parents.
News Release
Sept. 23, 2021
In a study supported by the National Institutes of Health, researchers propose changing a key measure in kidney disease diagnosis and treatment to eliminate the use of race as a variable, providing a non-biased kidney function test that does not compromise accuracy. The study suggests use of a blood lab test called cystatin C, which does not vary by a person’s race, to replace the current lab test called creatinine, which does.
News Release
Aug. 24, 2021
Diagnosed cases of type 1 and type 2 diabetes are surging among youth in the United States. From 2001 to 2017, the number of people under age 20 living with type 1 diabetes increased by 45%, and the number living with type 2 diabetes grew by 95%.
News Release
July 28, 2021
People with type 2 diabetes diagnosed during youth have a high risk of developing complications at early ages and have a greater chance of multiple complications within 15 years after diagnosis. The findings are the culmination of a first-of-its-kind trial funded largely by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), part of the National Institutes of Health.
News Release
June 1, 2021
GO MOMs, a new study supported by the National Institutes of Health aims to improve gestational diabetes screening and diagnosis by better understanding blood glucose levels throughout pregnancy.
News Release
March 31, 2021
In a clinical trial, early treatment with anti-vascular endothelial growth factor (VEGF) injections slowed diabetic retinopathy, a complication of diabetes that causes damage to the blood vessels of the light-sensitive tissue in the retina.
News Release
Feb. 12, 2021
Masks help protect the people wearing them from getting or spreading SARS-CoV-2, the virus that causes COVID-19, but now researchers from the National Institutes of Health have added evidence for yet another potential benefit for wearers: The humidity created inside the mask may help combat respiratory diseases such as COVID-19.
News Release
Jan. 21, 2021
People on a low-fat, plant-based diet ate fewer daily calories but had higher insulin and blood glucose levels, compared to when they ate a low-carbohydrate, animal-based diet, according to a small but highly controlled study at the National Institutes of Health. Led by researchers at the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), the study compared the effects of the two diets on calorie intake, hormone levels, body weight, and more.
News Release
Jan. 15, 2021
Description of the release: Scientists studying the body’s natural defenses against bacterial infection have identified a nutrient—taurine—that helps the gut recall prior infections and kill invading bacteria, such as Klebsiella pneumoniae (Kpn). The finding, published in the journal Cell by scientists from five institutes of the National Institutes of Health, could aid efforts seeking alternatives to antibiotics.
News Release
Jan. 8, 2021
NIH has begun the official transfer of the Office of Nutrition Research (ONR) from NIDDK to the NIH Office of the Director. This reorganization positions ONR to enhance engagement of the NIH Institutes and Centers in implementing the 2020-2030 Strategic Plan for NIH Nutrition Research.
News Release
Dec. 15, 2020
Surgical and injectable drug approaches are equally effective for treatment of bleeding inside the eye from proliferative diabetic retinopathy, according to a National Institutes of Health-supported clinical study from the DRCR Retina Network.
News Release
Sept. 30, 2020
A nationwide study funded by the National Institutes of Health will seek to discover the cause of several unusual forms of diabetes. Through research efforts at 20 U.S. research institutions, the study aims to discover new forms of diabetes, understand what makes them different, and identify their causes.
News Release
Aug. 26, 2020
A clinical trial at four pediatric diabetes centers in the United States has found that a new artificial pancreas system — which automatically monitors and regulates blood glucose levels — is safe and effective at managing blood glucose levels in children as young as age six with type 1 diabetes. The trial was funded by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), part of the National Institutes of Health.
News Release
July 24, 2020
Funded by the National Institutes of Health, six U.S. research institutions are launching the first-ever multicenter network to study diabetic foot ulcers, a common and burdensome complication of diabetes and the leading cause of lower limb amputations in the United States. The Diabetic Foot Consortium (DFC) aims to lay the foundation for a clinical trial network to test how to improve diabetic wound healing and prevent amputations among the 27 million American adults with diabetes.
News Release
June 25, 2020
In the largest exercise research program of its kind, researchers are poised to collect and turn data from nearly 2,600 volunteers into comprehensive maps of the molecular changes in the body due to exercise.
News Release
June 15, 2020
The National Institutes of Health has launched a centralized, secure enclave to store and study vast amounts of medical record data from people diagnosed with coronavirus disease across the country.
News Release
June 11, 2020
Scientists have developed a new test that can help identify people who are likely to develop hepatocellular carcinoma (HCC), the most common form of liver cancer. The approach uses a simple blood test to check for the patient’s previous exposure to certain viruses.
News Release
May 27, 2020
With a focus on precision nutrition, the 2020-2030 Strategic Plan for National Institutes of Health Nutrition Research reflects input from the nutrition research community and the wide range of nutrition research supported across NIH.
News Release
Feb. 26, 2020
NIH has launched a $1 million Technology Accelerator Challenge to spur the design and development of non-invasive, handheld, digital technologies to detect, diagnose and guide therapies for diseases with high global and public health impact. The challenge is focused on sickle cell disease, malaria and anemia.
News Release
Jan. 21, 2020
A National Institutes of Health study found that chronic treatment with mirabegron, a drug approved to treat overactive bladder, activated brown fat in a small group of healthy women and had several other beneficial metabolic effects. The research, led by Dr. Aaron Cypess at the NIH’s National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), was published online on January 21 in the Journal of Clinical Investigation.
News Release
Dec. 10, 2019
A new strategic plan from the National Institutes of Health outlines efforts to intensify ongoing HBV research with the goals of developing a cure and improving scientific understanding of the virus while creating improved strategies for screening and treating patients.
News Release
Nov. 14, 2019
A specific strain of a common bacteria found in most people with alcoholic hepatitis correlates with greater liver disease severity and mortality, according to a new study published in Nature. Alcoholic hepatitis is a serious form of alcohol-associated liver disease, and people with it have high levels of the bacterium Enterococcus faecalis (E. faecalis) in their gut. The study also found that a novel therapeutic approach that specifically targets the E. faecalis strain lessened alcohol-associated liver disease in mice.
News Release
Nov. 14, 2019
The National Institutes of Health has selected five scientists as Lasker Clinical Research Scholars, part of a joint initiative with the Albert and Mary Lasker Foundation, to foster the next generation of great clinical scientists. This highly competitive program provides talented, early stage researchers the opportunity to carry out independent clinical and translational research for five to seven years at NIH.
News Release
Oct. 16, 2019
A multicenter randomized clinical trial evaluating a new artificial pancreas system — which automatically monitors and regulates blood glucose levels — has found that the new system was more effective than existing treatments at controlling blood glucose levels in people with type 1 diabetes.
News Release
Oct. 7, 2019
The 2019 Nobel Prize in Physiology or Medicine has been awarded to National Institutes of Health grantees Gregg L. Semenza, M.D., Ph.D., of Johns Hopkins University, and William G. Kaelin Jr., M.D., of Dana-Farber Cancer Institute for their discoveries of how cells sense and adapt to oxygen availability.
News Release
Oct. 3, 2019
Of an estimated 6,500 to 7,000 known rare diseases, only a fraction – maybe 5% – have U.S. Food and Drug Administration-approved treatments. To increase that percentage, the National Institutes of Health has awarded approximately $31 million in grants in fiscal year 2019 to 20 teams – including five new groups – of scientists, clinicians, patients, families and patient advocates to study a wide range of rare diseases.
News Release
Sept. 26, 2019
To reverse the opioid crisis that continues to grip the nation, the National Institutes of Health has awarded $945 million in total fiscal year 2019 funding for grants, contracts and cooperative agreements across 41 states through the Helping to End Addiction Long-term Initiative or NIH HEAL Initiative. The trans-NIH research effort aims to improve treatments for chronic pain, curb the rates of opioid use disorder (OUD) and overdose and achieve long-term recovery from opioid addiction.
News Release
Sept. 9, 2019
Treating preterm infants with antibiotics for more than 20 months appears to promote the development of multidrug-resistant gut bacteria, suggests a study funded by the National Institutes of Health
News Release
Sept. 9, 2019
NIH-funded research project develops new method to preserve human livers for transplantation. Scientists have greatly extended the amount of time human livers can be stored for transplantation by modifying a previous protocol to extend the viability of rat livers.
