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NIH: National Institute of Diabetes and Digestive and Kidney Diseases NIH: National Institute of Diabetes and Digestive and Kidney Diseases
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  6. Neuromodulation & Motivation Section

Neuromodulation & Motivation Section

of the Diabetes, Endocrinology, & Obesity Branch

Andrew Lutas.
We use optical approaches to investigate receptor signaling in neural circuits controlling motivation and salience.
About Our Research

Select Publications

Semaglutide drives weight loss through cAMP-dependent mechanisms in GLP1R-expressing hindbrain neurons.
Gao C, Geneve IC, Rodriguez-Gonzalez S, Li C, McElhern K, Reitman ML, Lutas A, Krashes MJ.
Nat Metab (2026 Jun) 8:1330-1349. Abstract/Full Text
Transient cAMP production drives rapid and sustained spiking in brainstem parabrachial neurons to suppress feeding.
Singh Alvarado J, Lutas A, Madara JC, Isaac J, Lommer C, Massengill C, Andermann ML.
Neuron (2024 May 1) 112:1416-1425.e5. Abstract/Full Text
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Lab Members

Neuromodulation & Motivation Section lab members.
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Last Reviewed July 2024