S1pr2 KO Mouse

Also known as: S1pr2tm1Rlp, sphingosine-1-phosphate receptor 2 KO mouse, S1P2 KO mouse, Edg5 KO mouse

S1pr2 is a member of the sphingosine-1-phosphate G-protein coupled receptor family. S1pr2 KO mice exhibit deafness, seizures and are prone to B-cell lymphoma development. Double KO S1pr2/S1pr3 mice exhibit incompletely penetrant lethality as embryos. Learn more on PubMed.

Mice can be obtained from MMRRC.

Resource Details

https://www.mmrrc.org/catalog/sds.php?mmrrc_id=12830

tao@niddk.nih.gov

Proia, Richard

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Last Reviewed August 2023