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Ifechukwude Ebenuwa, M.D., M.H.Sc.

Headshot of Dr. Ifechukwude Ebenuwa.
Scientific Focus Areas: Clinical Research, Epidemiology

Professional Experience

  • M.H.Sc., Duke University School of Medicine, 2021
  • Staff Clinician, Assistant Research Physician, 2017
  • Faculty, NIH Inter-Institute Endocrinology Training Program, 2017
  • Endocrinology Fellowship, National Institutes of Health 2014-2017
  • Internal Medicine Residency, University of Chicago Northshore Program 2011-2014
  • M.D., University of Illinois College of Medicine Chicago, 2011
  • B.Sc., University of Illinois Urbana-Champaign, 2007

Research Goal

Research goals are to understand the clinical outcomes associated with antioxidant vitamin dysregulation in diabetes and obesity-related syndromes, across diverse demographic and socioeconomic cohorts/populations. Methodology includes observational, interventional and longitudinal studies investigating the physiologic, pharmacokinetic and cardiometabolic outcomes.

Current Research

Famine from Feast: Linking vitamin C, red blood cell fragility and diabetes

  • To investigate relationships between glycemic changes, vitamin C concentrations and measures of RBC rigidity (deformability) in type 2 diabetes.
  • To determine effect of vitamin C supplementation on measures of RBC rigidity in type 2 diabetes.

Urinary Vitamin C loss in Subjects with and without Diabetes.

  • To determine whether diabetic subjects have lower plasma vitamin C concentrations and increased urinary vitamin C excretion compared to nondiabetic controls.
  • Understand the demographic and clinical factors associated with low plasma vitamin C concentrations and increased urinary loss of vitamin C.

Applying Our Research

Enhanced understanding of the clinical consequences of antioxidant vitamin dysregulation in disease states may inform early nutritional strategies aimed at prevention/mitigation of disease complications.

Research in Plain Language

Vitamins C and E are an important vitamins used in many functions in the human body. Chronic diseases such as diabetes and obesity may decrease the levels and/or functioning of these vitamins. We are therefore conducting studies aimed at (1) understanding whether and how the function of these vitamins are altered in disease conditions such as diabetes and obesity, and (2) how these changes may affect disease progression and overall health and (3) determine whether or not early vitamin supplementation may be useful in preventing or slowing disease progression.

Last Reviewed July 2023