Ranganath Muniyappa, M.D., Ph.D.


A selection of recent and significant publications can be viewed below.

A Systematic Review Supporting the Endocrine Society Clinical Practice Guideline for the Management of Hyperglycemia in Adults Hospitalized for Noncritical Illness or Undergoing Elective Surgical Procedures.
Seisa MO, Saadi S, Nayfeh T, Muthusamy K, Shah SH, Firwana M, Hasan B, Jawaid T, Abd-Rabu R, Korytkowski MT, Muniyappa R, Antinori-Lent K, Donihi AC, Drincic AT, Luger A, Torres Roldan VD, Urtecho M, Wang Z, Murad MH.
J Clin Endocrinol Metab (2022 Jul 14) 107:2139-2147. Abstract/Full Text
Management of Hyperglycemia in Hospitalized Adult Patients in Non-Critical Care Settings: An Endocrine Society Clinical Practice Guideline.
Korytkowski MT, Muniyappa R, Antinori-Lent K, Donihi AC, Drincic AT, Hirsch IB, Luger A, McDonnell ME, Murad MH, Nielsen C, Pegg C, Rushakoff RJ, Santesso N, Umpierrez GE.
J Clin Endocrinol Metab (2022 Jul 14) 107:2101-2128. Abstract/Full Text
Enhancing the Trustworthiness of the Endocrine Society's Clinical Practice Guidelines.
McCartney CR, Corrigan MD, Drake MT, El-Hajj Fuleihan G, Korytkowski MT, Lash RW, Lieb DC, McCall AL, Muniyappa R, Piggott T, Santesso N, Schünemann HJ, Wiercioch W, McDonnell ME, Murad MH.
J Clin Endocrinol Metab (2022 Jul 14) 107:2129-2138. Abstract/Full Text
Postprandial Plasma Lipidomics Reveal Specific Alteration of Hepatic-derived Diacylglycerols in Nonalcoholic Fatty Liver Disease.
Velenosi TJ, Ben-Yakov G, Podszun MC, Hercun J, Etzion O, Yang S, Nadal C, Haynes-Williams V, Huang WA, González-Hódar L, Brychta RJ, Takahashi S, Akkaraju V, Krausz KW, Walter M, Cai H, Walter PJ, Muniyappa R, Chen KY, Gonzalez FJ, Rotman Y.
Gastroenterology (2022 Jun) 162:1990-2003. Abstract/Full Text
Endogenous Leptin Concentrations Poorly Predict Metreleptin Response in Patients With Partial Lipodystrophy.
Meral R, Malandrino N, Walter M, Neidert AH, Muniyappa R, Oral EA, Brown RJ.
J Clin Endocrinol Metab (2022 Mar 24) 107:e1739-e1751. Abstract/Full Text
Minimal Model-Derived Insulin Sensitivity Index Underestimates Insulin Sensitivity in Black Americans.
Fosam A, Yuditskaya S, Sarcone C, Grewal S, Fan H, Muniyappa R.
Diabetes Care (2021 Nov) 44:2586-2588. Abstract/Full Text
Mifepristone Improves Adipose Tissue Insulin Sensitivity in Insulin Resistant Individuals.
Gubbi S, Muniyappa R, Sharma ST, Grewal S, McGlotten R, Nieman LK.
J Clin Endocrinol Metab (2021 Apr 23) 106:1501-1515. Abstract/Full Text
When MINMOD Artifactually Interprets Strong Insulin Secretion as Weak Insulin Action.
Ha J, Muniyappa R, Sherman AS, Quon MJ.
Front Physiol (2021) 12:601894. Abstract/Full Text
Insulin sensitivity and pancreatic β-cell function in patients with primary aldosteronism.
Grewal S, Fosam A, Chalk L, Deven A, Suzuki M, Correa RR, Blau JE, Demidowich AP, Stratakis CA, Muniyappa R.
Endocrine (2021 Apr) 72:96-103. Abstract/Full Text
Apolipoprotein CIII and Angiopoietin-like Protein 8 are Elevated in Lipodystrophy and Decrease after Metreleptin.
Lightbourne M, Wolska A, Abel BS, Rother KI, Walter M, Kushchayeva Y, Auh S, Shamburek RD, Remaley AT, Muniyappa R, Brown RJ.
J Endocr Soc (2021 Feb 1) 5:bvaa191. Abstract/Full Text
Metabolic Syndrome and COVID 19: Endocrine-Immune-Vascular Interactions Shapes Clinical Course.
Bansal R, Gubbi S, Muniyappa R.
Endocrinology (2020 Oct 1) 161. Abstract/Full Text
Diabetes, Obesity, and Risk Prediction of Severe COVID-19.
Muniyappa R, Wilkins KJ.
J Clin Endocrinol Metab (2020 Oct 1) 105. Abstract/Full Text
A Pragmatic Approach to Inpatient Diabetes Management during the COVID-19 Pandemic.
Korytkowski M, Antinori-Lent K, Drincic A, Hirsch IB, McDonnell ME, Rushakoff R, Muniyappa R.
J Clin Endocrinol Metab (2020 Sep 1) 105. Abstract/Full Text
Endothelial dysfunction due to selective insulin resistance in vascular endothelium: insights from mechanistic modeling.
Muniyappa R, Chen H, Montagnani M, Sherman A, Quon MJ.
Am J Physiol Endocrinol Metab (2020 Sep 1) 319:E629-E646. Abstract/Full Text
Increased β-Cell Responsivity Independent of Insulin Sensitivity in Healthy African American Adults.
Armiyaw L, Sarcone C, Fosam A, Muniyappa R.
J Clin Endocrinol Metab (2020 Jul 1) 105:e2429-38. Abstract/Full Text
COVID-19 pandemic, coronaviruses, and diabetes mellitus.
Muniyappa R, Gubbi S.
Am J Physiol Endocrinol Metab (2020 May 1) 318:E736-E741. Abstract/Full Text
Reduced Insulin Clearance and Insulin-Degrading Enzyme Activity Contribute to Hyperinsulinemia in African Americans.
Fosam A, Sikder S, Abel BS, Tella SH, Walter MF, Mari A, Muniyappa R.
J Clin Endocrinol Metab (2020 Apr 1) 105:e1835-46. Abstract/Full Text
Metabolomic Analysis of the Effects of Leptin Replacement Therapy in Patients with Lipodystrophy.
Grewal S, Gubbi S, Fosam A, Sedmak C, Sikder S, Talluru H, Brown RJ, Muniyappa R.
J Endocr Soc (2020 Jan 1) 4:bvz022. Abstract/Full Text
Effects of growth hormone administration on luteinizing hormone secretion in healthy older men and women.
Muniyappa R, Sullivan SD, Tella SH, Abel BS, Harman SM, Blackman MR.
Physiol Rep (2017 Dec) 5. Abstract/Full Text
Plasma serpinB1 is related to insulin sensitivity but not pancreatic β-Cell function in non-diabetic adults.
Glicksman M, Asthana A, Abel BS, Walter MF, Skarulis MC, Muniyappa R.
Physiol Rep (2017 Mar) 5. Abstract/Full Text
Metreleptin therapy lowers plasma angiopoietin-like protein 3 in patients with generalized lipodystrophy.
Muniyappa R, Abel BS, Asthana A, Walter MF, Cochran EK, Remaley AT, Skarulis MC, Gorden P, Brown RJ.
J Clin Lipidol (2017 Mar-Apr) 11:543-550. Abstract/Full Text
Effect of Leptin Replacement on PCSK9 in ob/ob Mice and Female Lipodystrophic Patients.
Levenson AE, Haas ME, Miao J, Brown RJ, de Ferranti SD, Muniyappa R, Biddinger SB.
Endocrinology (2016 Apr) 157:1421-9. Abstract/Full Text
Last Reviewed July 2023