Mary Walter, Ph.D.
Scientific Focus Areas: Chemical Biology, Clinical Research


A selection of recent and significant publications can be viewed below.

Metreleptin-mediated improvements in insulin sensitivity are independent of food intake in humans with lipodystrophy.
Brown RJ, Valencia A, Startzell M, Cochran E, Walter PJ, Garraffo HM, Cai H, Gharib AM, Ouwerkerk R, Courville AB, Bernstein S, Brychta RJ, Chen KY, Walter M, Auh S, Gorden P.
J Clin Invest (2018 Aug 1) 128:3504-3516. Abstract/Full Text
Norepinephrine and T4 Are Predictors of Fat Mass Gain in Humans With Cold-Induced Brown Adipose Tissue Activation.
Begaye B, Piaggi P, Thearle MS, Haskie K, Walter M, Schlögl M, Bonfiglio S, Krakoff J, Vinales KL.
J Clin Endocrinol Metab (2018 Jul 1) 103:2689-2697. Abstract/Full Text
Canagliflozin triggers the FGF23/1,25-dihydroxyvitamin D/PTH axis in healthy volunteers in a randomized crossover study.
Blau JE, Bauman V, Conway EM, Piaggi P, Walter MF, Wright EC, Bernstein S, Courville AB, Collins MT, Rother KI, Taylor SI.
JCI Insight (2018 Apr 19) 3. Abstract/Full Text
Energy Expenditure and Hormone Responses in Humans After Overeating High-Fructose Corn Syrup Versus Whole-Wheat Foods.
Ibrahim M, Bonfiglio S, Schlögl M, Vinales KL, Piaggi P, Venti C, Walter M, Krakoff J, Thearle MS.
Obesity (Silver Spring) (2018 Jan) 26:141-149. Abstract/Full Text
Effects of Metreleptin in Pediatric Patients With Lipodystrophy.
Brown RJ, Meehan CA, Cochran E, Rother KI, Kleiner DE, Walter M, Gorden P.
J Clin Endocrinol Metab (2017 May 1) 102:1511-1519. Abstract/Full Text
Plasma serpinB1 is related to insulin sensitivity but not pancreatic β-Cell function in non-diabetic adults.
Glicksman M, Asthana A, Abel BS, Walter MF, Skarulis MC, Muniyappa R.
Physiol Rep (2017 Mar) 5. Abstract/Full Text
Pigment Epithelium-Derived Factor Declines in Response to an Oral Glucose Load and Is Correlated with Vitamin D and BMI but Not Diabetes Status in Children and Young Adults.
Sylvetsky AC, Issa NT, Chandran A, Brown RJ, Alamri HJ, Aitcheson G, Walter M, Rother KI.
Horm Res Paediatr (2017) 87:301-306. Abstract/Full Text
Metreleptin therapy lowers plasma angiopoietin-like protein 3 in patients with generalized lipodystrophy.
Muniyappa R, Abel BS, Asthana A, Walter MF, Cochran EK, Remaley AT, Skarulis MC, Gorden P, Brown RJ.
J Clin Lipidol (2017 Mar - Apr) 11:543-550. Abstract/Full Text
Hormonal responses to non-nutritive sweeteners in water and diet soda.
Sylvetsky AC, Brown RJ, Blau JE, Walter M, Rother KI.
Nutr Metab (Lond) (2016) 13:71. Abstract/Full Text
Persistent metabolic adaptation 6 years after "The Biggest Loser" competition.
Fothergill E, Guo J, Howard L, Kerns JC, Knuth ND, Brychta R, Chen KY, Skarulis MC, Walter M, Walter PJ, Hall KD.
Obesity (Silver Spring) (2016 Aug) 24:1612-9. Abstract/Full Text
Lipoprotein Particles in Adolescents and Young Women With PCOS Provide Insights Into Their Cardiovascular Risk.
Gourgari E, Lodish M, Shamburek R, Keil M, Wesley R, Walter M, Sampson M, Bernstein S, Khurana D, Lyssikatos C, Ten S, Dobs A, Remaley AT, Stratakis CA.
J Clin Endocrinol Metab (2015 Nov) 100:4291-8. Abstract/Full Text
Calorie for Calorie, Dietary Fat Restriction Results in More Body Fat Loss than Carbohydrate Restriction in People with Obesity.
Hall KD, Bemis T, Brychta R, Chen KY, Courville A, Crayner EJ, Goodwin S, Guo J, Howard L, Knuth ND, Miller BV 3rd, Prado CM, Siervo M, Skarulis MC, Walter M, Walter PJ, Yannai L.
Cell Metab (2015 Sep 1) 22:427-36. Abstract/Full Text
Myocardial Fat Accumulation Is Independent of Measures of Insulin Sensitivity.
Muniyappa R, Noureldin R, Ouwerkerk R, Liu EY, Madan R, Abel BS, Mullins K, Walter MF, Skarulis MC, Gharib AM.
J Clin Endocrinol Metab (2015 Aug) 100:3060-8. Abstract/Full Text
Increased 24-hour ad libitum food intake is associated with lower plasma irisin concentrations the following morning in adult humans.
Schlögl M, Piaggi P, Votruba SB, Walter M, Krakoff J, Thearle MS.
Appetite (2015 Jul) 90:154-9. Abstract/Full Text
Orbitofrontal response to drug-related stimuli after heroin administration.
Walter M, Denier N, Gerber H, Schmid O, Lanz C, Brenneisen R, Riecher-Rössler A, Wiesbeck GA, Scheffler K, Seifritz E, McGuire P, Fusar-Poli P, Borgwardt S.
Addict Biol (2015 May) 20:570-9. Abstract/Full Text
Urine protein profiling identified alpha-1-microglobulin and haptoglobin as biomarkers for early diagnosis of acute allograft rejection following kidney transplantation.
Stubendorff B, Finke S, Walter M, Kniemeyer O, von Eggeling F, Gruschwitz T, Steiner T, Ott U, Wolf G, Wunderlich H, Junker K.
World J Urol (2014 Dec) 32:1619-24. Abstract/Full Text
Impact of lithium treatment on FGF-23 serum concentrations in depressive patients.
Fakhri H, Ricken R, Adli M, Fajol A, Walter M, Föller M, Berlin Research Network of Depression., Lang F, Lang UE, Lange C.
J Clin Psychopharmacol (2014 Dec) 34:745-7. Abstract/Full Text
Distribution of immunoreactive glutamine synthetase in the adult human and mouse brain. Qualitative and quantitative observations with special emphasis on extra-astroglial protein localization.
Bernstein HG, Bannier J, Meyer-Lotz G, Steiner J, Keilhoff G, Dobrowolny H, Walter M, Bogerts B.
J Chem Neuroanat (2014 Nov) 61-62:33-50. Abstract/Full Text
Molecular analysis of Coxiella burnetii in Germany reveals evolution of unique clonal clusters.
Frangoulidis D, Walter MC, Antwerpen M, Zimmermann P, Janowetz B, Alex M, Böttcher J, Henning K, Hilbert A, Ganter M, Runge M, Münsterkötter M, Splettstoesser WD, Hanczaruk M.
Int J Med Microbiol (2014 Oct) 304:868-76. Abstract/Full Text
Diffusion tensor imaging in Alzheimer's disease and affective disorders.
Teipel SJ, Walter M, Likitjaroen Y, Schönknecht P, Gruber O.
Eur Arch Psychiatry Clin Neurosci (2014 Sep) 264:467-83. Abstract/Full Text
Altered prefrontal connectivity after acute heroin administration during cognitive control.
Schmidt A, Borgwardt S, Gerber H, Schmid O, Wiesbeck GA, Riecher-Rössler A, Bendfeldt K, Smieskova R, Lang UE, Rubia K, Walter M.
Int J Neuropsychopharmacol (2014 Sep) 17:1375-85. Abstract/Full Text
Usefulness of bioimpedance spectroscopy for detection of hypotensive episode during dialysis.
Ismail AH, Trué N, Gross T, Eilebrecht B, Walter M, Schlieper G, Eitner F, Floege J, Leonhardt S.
ASAIO J (2014 Sep-Oct) 60:570-5. Abstract/Full Text
125 Cases of duodenoduodenostomy in pancreas transplantation: a single-centre experience of an alternative enteric drainage.
Walter M, Jazra M, Kykalos S, Kuehn P, Michalski S, Klein T, Wunsch A, Viebahn R, Schenker P.
Transpl Int (2014 Aug) 27:805-15. Abstract/Full Text
Indium-111 labeled gold nanoparticles for in-vivo molecular targeting.
Ng QK, Olariu CI, Yaffee M, Taelman VF, Marincek N, Krause T, Meier L, Walter MA.
Biomaterials (2014 Aug) 35:7050-7. Abstract/Full Text
Evidence for an agitated-aggressive syndrome predating the onset of psychosis.
Huber CG, Smieskova R, Schroeder K, Studerus E, Harrisberger F, Aston J, Walter A, Walter M, Riecher-Rössler A, Borgwardt S.
Schizophr Res (2014 Aug) 157:26-32. Abstract/Full Text
Post-acute crisis text messaging outreach for suicide prevention: a pilot study.
Berrouiguet S, Gravey M, Le Galudec M, Alavi Z, Walter M.
Psychiatry Res (2014 Jul 30) 217:154-7. Abstract/Full Text
Clonal architecture of secondary acute myeloid leukemia defined by single-cell sequencing.
Hughes AE, Magrini V, Demeter R, Miller CA, Fulton R, Fulton LL, Eades WC, Elliott K, Heath S, Westervelt P, Ding L, Conrad DF, White BS, Shao J, Link DC, DiPersio JF, Mardis ER, Wilson RK, Ley TJ, Walter MJ, Graubert TA.
PLoS Genet (2014 Jul) 10:e1004462. Abstract/Full Text
Abnormal effective connectivity and psychopathological symptoms in the psychosis high-risk state.
Schmidt A, Smieskova R, Simon A, Allen P, Fusar-Poli P, McGuire PK, Bendfeldt K, Aston J, Lang UE, Walter M, Radue EW, Riecher-Rössler A, Borgwardt SJ.
J Psychiatry Neurosci (2014 Jul) 39:239-48. Abstract/Full Text
Management of shortened dental arches and periodontal health: 5-year results of a randomised trial.
Walter MH, Marré B, Vach K, Strub J, Mundt T, Stark H, Pospiech P, Wöstmann B, Heydecke G, Kern M, Hartmann S, Luthardt R, Huppertz J, Wolfart S, Hannak W.
J Oral Rehabil (2014 Jul) 41:515-22. Abstract/Full Text
Reduction of seclusion on a hospital-wide level: successful implementation of a less restrictive policy.
Jungfer HA, Schneeberger AR, Borgwardt S, Walter M, Vogel M, Gairing SK, Lang UE, Huber CG.
J Psychiatr Res (2014 Jul) 54:94-9. Abstract/Full Text
FOXA1 deletion in luminal epithelium causes prostatic hyperplasia and alteration of differentiated phenotype.
DeGraff DJ, Grabowska MM, Case TC, Yu X, Herrick MK, Hayward WJ, Strand DW, Cates JM, Hayward SW, Gao N, Walter MA, Buttyan R, Yi Y, Kaestner KH, Matusik RJ.
Lab Invest (2014 Jul) 94:726-39. Abstract/Full Text
Influence of physiological sources on the impedance cardiogram analyzed using 4D FEM simulations.
Ulbrich M, Mühlsteff J, Leonhardt S, Walter M.
Physiol Meas (2014 Jul) 35:1451-68. Abstract/Full Text
Utilization of baclofen in maintenance of alcohol abstinence in patients with alcohol dependence and alcoholic hepatitis with or without cirrhosis.
Yamini D, Lee SH, Avanesyan A, Walter M, Runyon B.
Alcohol Alcohol (2014 Jul-Aug) 49:453-6. Abstract/Full Text
Coordination chemistry of sterically encumbered pyrrolyl ligands to chromium(II): mono(pyrrolyl)chromium and diazachromocene formation.
Kreye M, Daniliuc CG, Freytag M, Jones PG, Walter MD.
Dalton Trans (2014 Jun 28) 43:9052-60. Abstract/Full Text
Group 4 metal complexes with new chiral pincer NHC-ligands: synthesis, structure and catalytic activity.
Zhao N, Hou G, Deng X, Zi G, Walter MD.
Dalton Trans (2014 Jun 14) 43:8261-72. Abstract/Full Text
Ultrasound assessment of cervical length at 18-21 weeks' gestation in an Australian obstetric population: comparison of transabdominal and transvaginal approaches.
Marren AJ, Mogra R, Pedersen LH, Walter M, Ogle RF, Hyett JA.
Aust N Z J Obstet Gynaecol (2014 Jun) 54:250-5. Abstract/Full Text
The IMPACT shirt: textile integrated and portable impedance cardiography.
Ulbrich M, Mühlsteff J, Sipilä A, Kamppi M, Koskela A, Myry M, Wan T, Leonhardt S, Walter M.
Physiol Meas (2014 Jun) 35:1181-96. Abstract/Full Text
Protocol for a prospective neuroimaging study investigating the supraspinal control of lower urinary tract function in healthy controls and patients with non-neurogenic lower urinary tract symptoms.
Walter M, Michels L, Kollias S, van Kerrebroeck PE, Kessler TM, Mehnert U.
BMJ Open (2014 May 21) 4:e004357. Abstract/Full Text
Pentadienyl chemistry of the heavy alkaline-earth metals revisited.
Reiners M, Fecker AC, Freytag M, Jones PG, Walter MD.
Dalton Trans (2014 May 14) 43:6614-7. Abstract/Full Text
Dysregulated expression of lipid storage and membrane dynamics factors in Tia1 knockout mouse nervous tissue.
Heck MV, Azizov M, Stehning T, Walter M, Kedersha N, Auburger G.
Neurogenetics (2014 May) 15:135-44. Abstract/Full Text
Non-imidazole histamine H3 receptor ligands incorporating antiepileptic moieties.
Sadek B, Schwed JS, Subramanian D, Weizel L, Walter M, Adem A, Stark H.
Eur J Med Chem (2014 Apr 22) 77:269-79. Abstract/Full Text
Sulforaphane protects from T cell-mediated autoimmune disease by inhibition of IL-23 and IL-12 in dendritic cells.
Geisel J, Brück J, Glocova I, Dengler K, Sinnberg T, Rothfuss O, Walter M, Schulze-Osthoff K, Röcken M, Ghoreschi K.
J Immunol (2014 Apr 15) 192:3530-9. Abstract/Full Text
Integrated proteomic and transcriptomic analysis of the Aedes aegypti eggshell.
Marinotti O, Ngo T, Kojin BB, Chou SP, Nguyen B, Juhn J, Carballar-Lejarazú R, Marinotti PN, Jiang X, Walter MF, Tu Z, Gershon PD, James AA.
BMC Dev Biol (2014 Apr 5) 14:15. Abstract/Full Text
Is tightly controlled disease activity possible with online patient-reported outcomes?
Walter MJ, Mohd Din SH, Hazes JM, Lesaffre E, Barendregt PJ, Luime JJ.
J Rheumatol (2014 Apr) 41:640-7. Abstract/Full Text
Unraveling the core-shell structure of ligand-capped Sn/SnOx nanoparticles by surface-enhanced nuclear magnetic resonance, Mössbauer, and X-ray absorption spectroscopies.
Protesescu L, Rossini AJ, Kriegner D, Valla M, de Kergommeaux A, Walter M, Kravchyk KV, Nachtegaal M, Stangl J, Malaman B, Reiss P, Lesage A, Emsley L, Copéret C, Kovalenko MV.
ACS Nano (2014 Mar 25) 8:2639-48. Abstract/Full Text
New talent: Europe.
Tamm M, Walter MD.
Dalton Trans (2014 Mar 21) 43:4196. Abstract/Full Text
[Long-term treatment of schizophrenia spectrum disorders: focus on pharmacotherapy].
Deutschenbaur L, Lambert M, Walter M, Naber D, Huber CG.
Nervenarzt (2014 Mar) 85:363-75; quiz 376-7. Abstract/Full Text
Robust sensor fusion of unobtrusively measured heart rate.
Wartzek T, Brüser C, Walter M, Leonhardt S.
IEEE J Biomed Health Inform (2014 Mar) 18:654-60. Abstract/Full Text