Jinfa Ying, Ph.D.


A selection of recent and significant publications can be viewed below.

Quantitative evaluation of positive ϕ angle propensity in flexible regions of proteins from three-bond J couplings.
Lee JH, Ying J, Bax A.
Phys Chem Chem Phys (2016 Feb 17) 18:5759-70. Abstract/Full Text
High accuracy of Karplus equations for relating three-bond J couplings to protein backbone torsion angles.
Li F, Lee JH, Grishaev A, Ying J, Bax A.
Chemphyschem (2015 Feb 23) 16:572-8. Abstract/Full Text
A maximum entropy approach to the study of residue-specific backbone angle distributions in α-synuclein, an intrinsically disordered protein.
Mantsyzov AB, Maltsev AS, Ying J, Shen Y, Hummer G, Bax A.
Protein Sci (2014 Sep) 23:1275-90. Abstract/Full Text
Homonuclear decoupling for enhancing resolution and sensitivity in NOE and RDC measurements of peptides and proteins.
Ying J, Roche J, Bax A.
J Magn Reson (2014 Apr) 241:97-102. Abstract/Full Text
Dissociation of the trimeric gp41 ectodomain at the lipid-water interface suggests an active role in HIV-1 Env-mediated membrane fusion.
Roche J, Louis JM, Grishaev A, Ying J, Bax A.
Proc Natl Acad Sci U S A (2014 Mar 4) 111:3425-30. Abstract/Full Text
Deuterium isotope shifts for backbone ¹H, ¹⁵N and ¹³C nuclei in intrinsically disordered protein α-synuclein.
Maltsev AS, Ying J, Bax A.
J Biomol NMR (2012 Oct) 54:181-91. Abstract/Full Text
Probing exchange kinetics and atomic resolution dynamics in high-molecular-weight complexes using dark-state exchange saturation transfer NMR spectroscopy.
Fawzi NL, Ying J, Torchia DA, Clore GM.
Nat Protoc (2012 Jul 19) 7:1523-33. Abstract/Full Text
Measurement of ¹⁵N relaxation rates in perdeuterated proteins by TROSY-based methods.
Lakomek NA, Ying J, Bax A.
J Biomol NMR (2012 Jul) 53:209-21. Abstract/Full Text
Impact of N-terminal acetylation of α-synuclein on its random coil and lipid binding properties.
Maltsev AS, Ying J, Bax A.
Biochemistry (2012 Jun 26) 51:5004-13. Abstract/Full Text
Imino hydrogen positions in nucleic acids from density functional theory validated by NMR residual dipolar couplings.
Grishaev A, Ying J, Bax A.
J Am Chem Soc (2012 Apr 25) 134:6956-9. Abstract/Full Text
Atomic-resolution dynamics on the surface of amyloid-β protofibrils probed by solution NMR.
Fawzi NL, Ying J, Ghirlando R, Torchia DA, Clore GM.
Nature (2011 Oct 30) 480:268-72. Abstract/Full Text
Measurement of (1)H-(15)N and (1)H-(13)C residual dipolar couplings in nucleic acids from TROSY intensities.
Ying J, Wang J, Grishaev A, Yu P, Wang YX, Bax A.
J Biomol NMR (2011 Sep) 51:89-103. Abstract/Full Text
Structural discrimination in small molecules by accurate measurement of long-range proton-carbon NMR residual dipolar couplings.
Trigo-Mouriño P, Navarro-Vázquez A, Ying J, Gil RR, Bax A.
Angew Chem Int Ed Engl (2011 Aug 8) 50:7576-80. Abstract/Full Text
Kinetics of amyloid beta monomer-to-oligomer exchange by NMR relaxation.
Fawzi NL, Ying J, Torchia DA, Clore GM.
J Am Chem Soc (2010 Jul 28) 132:9948-51. Abstract/Full Text
Chemical shift anisotropy of imino 15N nuclei in Watson-Crick base pairs from magic angle spinning liquid crystal NMR and nuclear spin relaxation.
Grishaev A, Yao L, Ying J, Pardi A, Bax A.
J Am Chem Soc (2009 Jul 15) 131:9490-1. Abstract/Full Text
Improved accuracy of 15N-1H scalar and residual dipolar couplings from gradient-enhanced IPAP-HSQC experiments on protonated proteins.
Yao L, Ying J, Bax A.
J Biomol NMR (2009 Mar) 43:161-70. Abstract/Full Text
NMR determination of amide N-H equilibrium bond length from concerted dipolar coupling measurements.
Yao L, Vögeli B, Ying J, Bax A.
J Am Chem Soc (2008 Dec 10) 130:16518-20. Abstract/Full Text
Solution structure of tRNAVal from refinement of homology model against residual dipolar coupling and SAXS data.
Grishaev A, Ying J, Canny MD, Pardi A, Bax A.
J Biomol NMR (2008 Oct) 42:99-109. Abstract/Full Text
Magnetic field induced residual dipolar couplings of imino groups in nucleic acids from measurements at a single magnetic field.
Ying J, Grishaev A, Latham MP, Pardi A, Bax A.
J Biomol NMR (2007 Oct) 39:91-6. Abstract/Full Text
Limits on variations in protein backbone dynamics from precise measurements of scalar couplings.
Vögeli B, Ying J, Grishaev A, Bax A.
J Am Chem Soc (2007 Aug 1) 129:9377-85. Abstract/Full Text
Mixed-time parallel evolution in multiple quantum NMR experiments: sensitivity and resolution enhancement in heteronuclear NMR.
Ying J, Chill JH, Louis JM, Bax A.
J Biomol NMR (2007 Mar) 37:195-204. Abstract/Full Text
Design, synthesis, and biological evaluation of new cyclic melanotropin peptide analogues selective for the human melanocortin-4 receptor.
Ying J, Gu X, Cai M, Dedek M, Vagner J, Trivedi DB, Hruby VJ.
J Med Chem (2006 Nov 16) 49:6888-96. Abstract/Full Text
2'-hydroxyl proton positions in helical RNA from simultaneously measured heteronuclear scalar couplings and NOEs.
Ying J, Bax A.
J Am Chem Soc (2006 Jul 5) 128:8372-3. Abstract/Full Text
Carbon-13 chemical shift anisotropy in DNA bases from field dependence of solution NMR relaxation rates.
Ying J, Grishaev A, Bax A.
Magn Reson Chem (2006 Mar) 44:302-10. Abstract/Full Text