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NIH: National Institute of Diabetes and Digestive and Kidney Diseases NIH: National Institute of Diabetes and Digestive and Kidney Diseases
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  6. Section on Motivational Processes Underlying Appetite

Section on Motivational Processes Underlying Appetite

of the Diabetes, Endocrinology, & Obesity Branch

Michael J. Krashes, Ph.D.
Our lab aims to better understand the neural underpinnings of hunger by interrogating and recording activity of specific subsets of cells under distinct contexts of feeding behavior.
About Our Research

Select Publications

Semaglutide drives weight loss through cAMP-dependent mechanisms in GLP1R-expressing hindbrain neurons.
Gao C, Geneve IC, Rodriguez-Gonzalez S, Li C, McElhern K, Reitman ML, Lutas A, Krashes MJ.
Nat Metab (2026 Jun) 8:1330-1349. Abstract/Full Text
A hypothalamic circuit that modulates feeding and parenting behaviours.
Alcantara IC, Li C, Gao C, Rodriguez González S, Mickelsen LE, Papas BN, Goldschmidt AI, Cohen IM, Mazzone CM, de Araujo Salgado I, Piñol RA, Xiao C, Karolczak EO, Li JL, Cui G, Reitman ML, Krashes MJ.
Nature (2025 Sep) 645:981-990. Abstract/Full Text
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Lab Members
Last Reviewed July 2024