Genetics and Metabolism Section

of the Liver Diseases Branch

Our laboratory focuses on the genetics and cell biology of iron uptake and utilization in eukaryotes.

Select Publications

Iron Chaperone Poly rC Binding Protein 1 Protects Mouse Liver From Lipid Peroxidation and Steatosis.
Protchenko O, Baratz E, Jadhav S, Li F, Shakoury-Elizeh M, Gavrilova O, Ghosh MC, Cox JE, Maschek JA, Tyurin VA, Tyurina YY, Bayir H, Aron AT, Chang CJ, Kagan VE, Philpott CC.
Hepatology (2021 Mar) 73:1176-1193. Abstract/Full Text
A PCBP1-BolA2 chaperone complex delivers iron for cytosolic [2Fe-2S] cluster assembly.
Patel SJ, Frey AG, Palenchar DJ, Achar S, Bullough KZ, Vashisht A, Wohlschlegel JA, Philpott CC.
Nat Chem Biol (2019 Sep) 15:872-881. Abstract/Full Text
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Lab Members

Members of the Genetics and Metabolism Section 
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