Renewal of Human Pancreas Analysis Program for Type 2 Diabetes (HPAP-T2D)

May 2023 Council

Lead Division/Office


Point(s) of Contact

Olivier Blondel

Executive Summary

This Funding Opportunity Announcement (FOA) will build on the progress and success of the first cycle of funding and will invite a single cooperative agreement application to continue HPAP-T2D's deep and multiplexed phenotyping of pancreatic tissues recovered from donors with T2D and related metabolic disorders. Specifically, the initiative will task the existing HPAP-T2D team to continue with: 1) identifying, collecting, and intensively characterizing primary pancreatic tissues from patients with T2D and related forms of islet dysfunction, as well as matched controls; and 2) analyzing, organizing, and sharing the data resulting from the study of these tissues through expansion of the existing PANC-DB open-access resource database.