Tomás Cabeza de Baca, Ph.D.

Staff Scientist:
Obesity and Diabetes Clinical Research Section, Phoenix Epidemiology & Clinical Research Branch
Scientific Focus Areas: Social and Behavioral Sciences, Health Disparities, Epidemiology
Clinical Trials
Open studies conducted by NIDDK Principal Investigators appear below. Study statuses may include the following:
- Open: Recruiting - Currently recruiting participants and open to everyone who meets eligibility criteria.
- Open: Active, Not Recruiting - Participants are receiving an intervention or being examined, however new participants are not being recruited or enrolled.
- Open: Enrolling by Invitation - People in a particular population were selected in advance and invited to participate. The study is not open to everyone who meets the eligibility criteria.
- Open: Available for Expanded Access - Patients who are not participants in the clinical study may be able to gain access to the drug, biologic, or medical device being studied.
Studies Seeking Patients
The Effects of Increasing Caloric Intake on Diet-Induced Thermogenesis and 24h Energy Expenditure
Background:
Diet-induced thermogenesis (DIT) is the amount of energy one s body uses to eat food, absorb
the nutrients from the food, and process those nutrients. Researchers would like to
understand more about how changing the balances of protein, fat, carbohydrates, and total
calories in the diet can affect DIT.
Objective:
To learn how different diets can change a person s DIT.
Eligibility:
Healthy people aged 18 to 60 years who have not intentionally lost weight in the past 6
months.
Design:
Participants will stay in a clinic for about 34 days. They will eat only the food provided.
They will receive 8 different diets during the study, including 7 test diets.
Participants will undergo multiple tests.
They will be screened with blood and urine tests and a test of their heart function.
During the first few days:
Their waist, thigh, and neck circumference will be measured.
They will have a DXA scan: They will lie on a padded table for about 20 minutes while an
instrument measures the amount of fat in their body.
They will be tested for diabetes.
They will answer questionnaires about topics including eating behavior, hunger, and stress.
Throughout the study:
Their weight will be measured daily.
Blood tests will be repeated.
They will stay in a metabolic chamber a total of 9 times. They will remain in a closed room
for 24 hours while researchers monitor the room temperature and levels of oxygen and carbon
dioxide. Participants will collect all their urine for each 24-hour period.
The trial is Open with a status of Recruiting.
Investigator: Tomas Cabeza De Baca
Referral Contacts: Office of Participant Recruitment-NIDDK (602) 200-5315