Joining Soon: Priyanka Narayan, Ph.D.

Dr. Narayan and the Human Disease Section is joining the Genetics and Biochemistry Branch in April 2020.

Photo of Priyanka Narayan.

Contact Info

Email: priyanka.narayan@nih.gov

Open Positions

Postdoctoral fellow, graduate student, post-baccalaureate, and technician positions are available. We are especially interested in those with experience in induced pluripotent stem cell work. Please contact priyanka.narayan@nih.gov for more information.

Current Research

Our lab studies the ways in which neurodegenerative disease risk factors alter fundamental cellular pathways to increase susceptibility to diseases like Alzheimer’s disease. We are pursuing these scientific questions with the ultimate goal of identifying novel therapeutic or preventative mechanisms for neurodegenerative diseases. Our research combines techniques from biochemistry, genetic screening, and neurobiology in human induced pluripotent stem cell-derived tissues.

Select Publications

Combating neurodegenerative disease using chemical probes and model systems
Narayan, P.*, Ehsani, S.*, Lindquist, S.
Nature Chemical Biology (2014) Abstract/Full Text
Rare individual amyloid-β oligomers act on astrocytes to initiate neuronal damage
Narayan, P.*, Holmstrom, K.M.*, Kim, D.H., Whitcomb, D.J., Wilson, M.R., Wood, N.W., Dobson, C.M., Cho, K., Abramov, A.Y., Klenerman, D.
Biochemistry (2014) Abstract/Full Text
Single molecule imaging of the interaction between amyloid-β peptides and the membranes of hippocampal cells
Narayan, P.*, Ganzinger, K.A.*, McColl, J.T., Qamar, S., St. George-Hyslop, P.G., Dobson C.,M., Klenerman, D.
Journal of the American Chemical Society (2013) Abstract/Full Text
The extracellular chaperone clusterin sequesters oligomeric forms of the Alzheimer’s disease-associated Aβ1-40 peptide
Narayan, P., Orte, A., Clarke, R.W., Bolognesi, B., Hook, S., Ganzinger, K.A., Meehan, S., Wilson, M.R., Dobson, C.M., Klenerman, D. Nature Structural and Molecular Biology (2012) Abstract/Full Text
Amyloid-β oligomers are sequestered by both intracellular and extracellular chaperones
Narayan, P., Meehan, S., Carver, J.A., Wilson, M.R., Dobson, C.M., Klenerman, D.
Biochemistry (2012) Abstract/Full Text