Using chemical biology to develop new tools to interrogate cell surface proteins and their signaling

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Improved GPCR ligands from nanobody tethering.
Cheloha RW, Fischer FA, Woodham AW, Daley E, Suminski N, Gardella TJ, Ploegh HL.
Nat Commun (2020 Apr 29) 11:2087. Abstract/Full Text
Exploring cellular biochemistry with nanobodies.
Cheloha RW, Harmand TJ, Wijne C, Schwartz TU, Ploegh HL.
J Biol Chem (2020 Nov 6) 295:15307-15327. Abstract/Full Text
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