Because of a lapse in government funding, the information on this website may not be up to date, transactions submitted via the website may not be processed, and the agency may not be able to respond to inquiries until appropriations are enacted.
The NIH Clinical Center (the research hospital of NIH) is open. For more details about its operating status, please visit cc.nih.gov.
Updates regarding government operating status and resumption of normal operations can be found at opm.gov.

U.S. flag

An official website of the United States government

NIH: National Institute of Diabetes and Digestive and Kidney Diseases NIH: National Institute of Diabetes and Digestive and Kidney Diseases 75 years: 1950-2025 75 years: 1950-2025
  1. Home
  2. Research & Funding
  3. Research at NIDDK
  4. Labs & Branches
  5. Laboratory of Bioorganic Chemistry
  6. Chemical Biology in Signaling Section

Chemical Biology in Signaling Section

of the Laboratory of Bioorganic Chemistry

Ross Cheloha.
Using chemical biology to develop new tools to interrogate cell surface proteins and their signaling
About Our Research

Select Publications

Chemically Induced Dimerization via Nanobody Binding Facilitates in Situ Ligand Assembly and On-Demand GPCR Activation.
Saha SJ, Cheloha RW.
JACS Au (2024 Dec 23) 4:4780-4789. Abstract/Full Text
Highly biased agonism for GPCR ligands via nanobody tethering.
Sachdev S, Creemer BA, Gardella TJ, Cheloha RW.
Nat Commun (2024 Jun 1) 15:4687. Abstract/Full Text
View More Publications

Lab Members

Chemical Biology Signaling Group photo 2024
View Our Lab Members
Join Us
Last Reviewed February 2025