Publications
A selection of recent and significant publications can be viewed below.
Select Publications
- Rapid Covalent Labeling of Membrane Proteins on Living Cells Using a Nanobody-Epitope Tag Pair.
- Cabalteja CC, Sachdev S, Cheloha RW.
- Bioconjug Chem (2022 Oct 19) 33:1867-1875. Abstract/Full Text
- Characterization of a Nanobody-Epitope Tag Interaction and Its Application for Receptor Engineering.
- Cabalteja CC, Sachdev S, Cheloha RW.
- ACS Chem Biol (2022 Aug 19) 17:2296-2303. Abstract/Full Text
- Strategies for targeting cell surface proteins using multivalent conjugates and chemical biology.
- Sachdev S, Cabalteja CC, Cheloha RW.
- Methods Cell Biol (2021) 166:205-222. Abstract/Full Text
- Exploring cellular biochemistry with nanobodies.
- Cheloha RW, Harmand TJ, Wijne C, Schwartz TU, Ploegh HL.
- J Biol Chem (2020 Nov 6) 295:15307-15327. Abstract/Full Text
- Improved GPCR ligands from nanobody tethering.
- Cheloha RW, Fischer FA, Woodham AW, Daley E, Suminski N, Gardella TJ, Ploegh HL.
- Nat Commun (2020 Apr 29) 11:2087. Abstract/Full Text
Additional Publications
- Activity-based, bioorthogonal imaging of phospholipase D reveals spatiotemporal dynamics of GPCR-Gq signaling.
- Liang D, Cheloha RW, Watanabe T, Gardella TJ, Baskin JM.
- Cell Chem Biol (2022 Jan 20) 29:67-73.e3. Abstract/Full Text
- A nanobody that recognizes a 14-residue peptide epitope in the E2 ubiquitin-conjugating enzyme UBC6e modulates its activity.
- Ling J, Cheloha RW, McCaul N, Sun ZJ, Wagner G, Ploegh HL.
- Mol Immunol (2019 Oct) 114:513-523. Abstract/Full Text
- Recognition of Class II MHC Peptide Ligands That Contain β-Amino Acids.
- Cheloha RW, Woodham AW, Bousbaine D, Wang T, Liu S, Sidney J, Sette A, Gellman SH, Ploegh HL.
- J Immunol (2019 Sep 15) 203:1619-1628. Abstract/Full Text
- Internalization of Influenza Virus and Cell Surface Proteins Monitored by Site-Specific Conjugation of Protease-Sensitive Probes.
- Cheloha RW, Li Z, Bousbaine D, Woodham AW, Perrin P, Volarić J, Ploegh HL.
- ACS Chem Biol (2019 Aug 16) 14:1836-1844. Abstract/Full Text
- Receptor selectivity from minimal backbone modification of a polypeptide agonist.
- Liu S, Cheloha RW, Watanabe T, Gardella TJ, Gellman SH.
- Proc Natl Acad Sci U S A (2018 Dec 4) 115:12383-12388. Abstract/Full Text
- Nanobody-Antigen Conjugates Elicit HPV-Specific Antitumor Immune Responses.
- Woodham AW, Cheloha RW, Ling J, Rashidian M, Kolifrath SC, Mesyngier M, Duarte JN, Bader JM, Skeate JG, Da Silva DM, Kast WM, Ploegh HL.
- Cancer Immunol Res (2018 Jul) 6:870-880. Abstract/Full Text
- Development of Potent, Protease-Resistant Agonists of the Parathyroid Hormone Receptor with Broad β Residue Distribution.
- Cheloha RW, Chen B, Kumar NN, Watanabe T, Thorne RG, Li L, Gardella TJ, Gellman SH.
- J Med Chem (2017 Nov 9) 60:8816-8833. Abstract/Full Text
- Rapid capture and labeling of cells on single domain antibodies-functionalized flow cell.
- Chen GY, Li Z, Duarte JN, Esteban A, Cheloha RW, Theile CS, Fink GR, Ploegh HL.
- Biosens Bioelectron (2017 Mar 15) 89:789-794. Abstract/Full Text
- Backbone Modification of a Parathyroid Hormone Receptor-1 Antagonist/Inverse Agonist.
- Cheloha RW, Watanabe T, Dean T, Gellman SH, Gardella TJ.
- ACS Chem Biol (2016 Oct 21) 11:2752-2762. Abstract/Full Text
- PTH receptor-1 signalling-mechanistic insights and therapeutic prospects.
- Cheloha RW, Gellman SH, Vilardaga JP, Gardella TJ.
- Nat Rev Endocrinol (2015 Dec) 11:712-24. Abstract/Full Text
- Consequences of periodic α-to-β(3) residue replacement for immunological recognition of peptide epitopes.
- Cheloha RW, Sullivan JA, Wang T, Sand JM, Sidney J, Sette A, Cook ME, Suresh M, Gellman SH.
- ACS Chem Biol (2015 Mar 20) 10:844-54. Abstract/Full Text
- Backbone modification of a polypeptide drug alters duration of action in vivo.
- Cheloha RW, Maeda A, Dean T, Gardella TJ, Gellman SH.
- Nat Biotechnol (2014 Jul) 32:653-5. Abstract/Full Text
- A new dehydrogenase from Clostridium acetobutylicum for asymmetric synthesis: dynamic reductive kinetic resolution entry into the Taxotère side chain.
- Applegate GA, Cheloha RW, Nelson DL, Berkowitz DB.
- Chem Commun (Camb) (2011 Feb 28) 47:2420-2. Abstract/Full Text