Mammalian Developmental Biology Section

of the Laboratory of Cellular and Developmental Biology

We study maternal factors that promote folliculogenesis, ensure fertilization, and sustain cleavage-stage development in mice.

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Glycan-Independent Gamete Recognition Triggers Egg Zinc Sparks and ZP2 Cleavage to Prevent Polyspermy.
Tokuhiro K, Dean J.
Dev Cell (2018 Sep 10) 46:627-640.e5. Abstract/Full Text
BTBD18 Regulates a Subset of piRNA-Generating Loci through Transcription Elongation in Mice.
Zhou L, Canagarajah B, Zhao Y, Baibakov B, Tokuhiro K, Maric D, Dean J.
Dev Cell (2017 Mar 13) 40:453-466.e5. Abstract/Full Text
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