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Mammalian Developmental Biology Section

of the Laboratory of Cellular & Developmental Biology

Jurrien Dean.
We study maternal factors that promote folliculogenesis, ensure fertilization, and sustain cleavage-stage development in mice.
About Our Research

Select Publications

Different populations of mouse egg cortical vesicles are responsible for post-fertilization zinc sparks and proteolysis of the zona pellucida.
José O, Baibakov B, Dean J.
iScience (2025 Jun 20) 28:112606. Abstract/Full Text
RNA helicase D1PAS1 resolves R-loops and forms a complex for mouse pachytene piRNA biogenesis required for male fertility.
Choi H, Zhou L, Zhao Y, Dean J.
Nucleic Acids Res (2024 Oct 28) 52:11973-11994. Abstract/Full Text
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Lab Members

Mammalian Developmental Biology Section lab members
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Last Reviewed April 2025