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Mammalian Developmental Biology Section

of the Laboratory of Cellular & Developmental Biology

Jurrien Dean. Jurrien Dean, M.D., NIH Distinguished Investigator

Section Chief

jurrien.dean@nih.gov
We study maternal factors that promote folliculogenesis, ensure fertilization, and sustain cleavage-stage development in mice.
About Our Research

Select Publications

RNA helicase D1PAS1 resolves R-loops and forms a complex for mouse pachytene piRNA biogenesis required for male fertility.
Choi H, Zhou L, Zhao Y, Dean J.
Nucleic Acids Res (2024 Oct 28) 52:11973-11994. Abstract/Full Text
DIS3 ribonuclease is essential for spermatogenesis and male fertility in mice.
Wang Z, Wu D, Xu X, Yu G, Li N, Wang X, Li JL, Dean J.
Development (2024 Jul 1) 151. Abstract/Full Text
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Lab Members

Mammalian Developmental Biology Section lab members
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Last Reviewed April 2025