Publications

A selection of recent and significant publications can be viewed below.

OPA1 helical structures give perspective to mitochondrial dysfunction.: Nyenhuis SB, Wu X, Strub MP, Yim YI, Stanton AE, Baena V, Syed ZA, Canagarajah B, Hammer JA, Hinshaw JE.; Nature (2023 Aug) 620:1109-1116. Abstract/Full Text
Visualization of Sparsely-populated Lower-order Oligomeric States of Human Mitochondrial Hsp60 by Cryo-electron Microscopy.: Wälti MA, Canagarajah B, Schwieters CD, Clore GM.; J Mol Biol (2021 Dec 3) 433:167322. Abstract/Full Text
Cryo-EM of the dynamin polymer assembled on lipid membrane.: Kong L, Sochacki KA, Wang H, Fang S, Canagarajah B, Kehr AD, Rice WJ, Strub MP, Taraska JW, Hinshaw JE.; Nature (2018 Aug) 560:258-262. Abstract/Full Text
BTBD18 Regulates a Subset of piRNA-Generating Loci through Transcription Elongation in Mice.: Zhou L, Canagarajah B, Zhao Y, Baibakov B, Tokuhiro K, Maric D, Dean J.; Dev Cell (2017 Mar 13) 40:453-466.e5. Abstract/Full Text
Genetic mosaics and time-lapse imaging identify functions of histone H3.3 residues in mouse oocytes and embryos.: Zhou L, Baibakov B, Canagarajah B, Xiong B, Dean J.; Development (2017 Feb 1) 144:519-528. Abstract/Full Text
The clathrin adaptor complexes as a paradigm for membrane-associated allostery.: Canagarajah BJ, Ren X, Bonifacino JS, Hurley JH.; Protein Sci (2013 May) 22:517-29. Abstract/Full Text
Structural basis for recruitment and activation of the AP-1 clathrin adaptor complex by Arf1.: Ren X, Farías GG, Canagarajah BJ, Bonifacino JS, Hurley JH.; Cell (2013 Feb 14) 152:755-67. Abstract/Full Text
Coordinated activation of the Rac-GAP β2-chimaerin by an atypical proline-rich domain and diacylglycerol.: Gutierrez-Uzquiza A, Colon-Gonzalez F, Leonard TA, Canagarajah BJ, Wang H, Mayer BJ, Hurley JH, Kazanietz MG.; Nat Commun (2013) 4:1849. Abstract/Full Text
Solution structure of the ESCRT-I and -II supercomplex: implications for membrane budding and scission.: Boura E, Różycki B, Chung HS, Herrick DZ, Canagarajah B, Cafiso DS, Eaton WA, Hummer G, Hurley JH.; Structure (2012 May 9) 20:874-86. Abstract/Full Text
Dynamics of cholesterol exchange in the oxysterol binding protein family.: Canagarajah BJ, Hummer G, Prinz WA, Hurley JH.; J Mol Biol (2008 May 2) 378:737-48. Abstract/Full Text
Phospholipase Cgamma/diacylglycerol-dependent activation of beta2-chimaerin restricts EGF-induced Rac signaling.: Wang H, Yang C, Leskow FC, Sun J, Canagarajah B, Hurley JH, Kazanietz MG.; EMBO J (2006 May 17) 25:2062-74. Abstract/Full Text
Structural mechanism for lipid activation of the Rac-specific GAP, beta2-chimaerin.: Canagarajah B, Leskow FC, Ho JY, Mischak H, Saidi LF, Kazanietz MG, Hurley JH.; Cell (2004 Oct 29) 119:407-18. Abstract/Full Text
Structural genomics and signaling domains.: Hurley JH, Anderson DE, Beach B, Canagarajah B, Ho YS, Jones E, Miller G, Misra S, Pearson M, Saidi L, Suer S, Trievel R, Tsujishita Y.; Trends Biochem Sci (2002 Jan) 27:48-53. Abstract/Full Text
The structure of active serpin 1K from Manduca sexta.: Li J, Wang Z, Canagarajah B, Jiang H, Kanost M, Goldsmith EJ.; Structure (1999 Jan 15) 7:103-9. Abstract/Full Text
Structural basis of inhibitor selectivity in MAP kinases.: Wang Z, Canagarajah BJ, Boehm JC, Kassisà S, Cobb MH, Young PR, Abdel-Meguid S, Adams JL, Goldsmith EJ.; Structure (1998 Sep 15) 6:1117-28. Abstract/Full Text
Phosphorylation of the MAP kinase ERK2 promotes its homodimerization and nuclear translocation.: Khokhlatchev AV, Canagarajah B, Wilsbacher J, Robinson M, Atkinson M, Goldsmith E, Cobb MH.; Cell (1998 May 15) 93:605-15. Abstract/Full Text
Activation mechanism of the MAP kinase ERK2 by dual phosphorylation.: Canagarajah BJ, Khokhlatchev A, Cobb MH, Goldsmith EJ.; Cell (1997 Sep 5) 90:859-69. Abstract/Full Text

Last Reviewed August 2024